80701-6
CD27- cells/CD3+CD8+ (T8 suppressor cells) cells in Blood
Active
Part Descriptions
LP100021-7 Cells.CD3+CD8+
HIV infection decreases the number of CD3+ CD4+ lymphocytes (also called CD4 T cells or T4 helper cells) while increasing (momentarily) the numbers of CD3+CD8+ lymphocytes (called CD8 T lymphocytes or cytotoxic T cells). Thus the ratio of CD4/CD8 lymphocytes is decreased. These counts are used for prognostic purposes and to guide in the retroviral therapy. CDC has emphasized since 1997 that the number of CD3+ lymphocytes is necessary in addition to the number of CD4+ cells to reliably identify the T4 helper cells and the number of CD8+ cells. Laboratory reports that include only CD4 or only CD8 in their nomenclature are most likely really measuring CD3+CD4+ cells and CD3+CD8+ cells, respectively.
Source: Regenstrief Help
LP204140-0 Cells.CD27-
CD27 and CD45RA are both lymphocyte cell surface markers that can be used to classify T-cells into various subsets. Expression of CD27 is characteristic of naive T-cells and some subsets of memory T-cells, while lack of CD27 is characteristic of effector T-cells. PMID: 19454729. CD45RA is characteristic of resting or naive T-cells. Cells expressing both CD27+CD45RA+ are undifferentiated (naive), CD27+CD45RA- T-cells are at an early stage of differentiation and exhibit characteristics of memory T cells, whereas CD27-CD45RA- T-cells are highly differentiated and have characteristics of both memory and effector T-cells. PMID: 12023349 PMID: 21788446
Source: Regenstrief LOINC
LP17729-2 CD8
Found on T-suppressor/cytotoxic cells and some Natural Killer cells; Associated with some mature T-cell neoplasms; Large granular lymphocytosis
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Cells.CD27-/Cells.CD3+CD8+
- Property
- NFr
- Time
- Pt
- System
- Bld
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- CD27- cells/CD3+CD8+ (T8 suppressor cells) cells in Blood
- Short Name
- CD27- cells/CD3+CD8+ Cll NFr Bld
- Display Name
- CD27- cells/CD3+CD8+ (T8 suppressor cells) cells (Bld)
- Consumer Name Alpha Get Info
- CD27- cells/CD3+CD8+ (T8 Suppressor Cells) Cells, Blood
Basic Attributes
- Class
- CELLMARK
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.79 (NAM)
- Change Reason
- Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
- Order vs. Observation
- Observation
Member of these Panels
LOINC | Long Common Name |
---|---|
80720-6 | T-cell naive and memory and effector (CD27 and CD45RA) subsets panel - Blood |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Κύτταρα.CD27-/Κύτταρα.CD3+CD8+: Synonyms: CD27 CD3 CD8 NFr Κύτταρα Κύτταρα.CD27 Κύτταρα.CD27- Κύτταρα.CD3 Κύτταρα.CD3+CD8+ |
es-ES | Spanish (Spain) | Linfocitos CD27-/Células CD3+CD8+: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Cells.CD27- / 100 Cells.CD3 + CD8 +: |
fr-FR | French (France) | CD27-/100 cellules CD3+CD8+: |
it-IT | Italian (Italy) | Cellule.CD27-/Cellule.CD3+CD8+: Synonyms: Cellule CD27 Cellule CD27- Cellule CD3 Cellule CD3+CD8+ Cellule CD3+CD8+ (cellule soppressore T8) Frazione numerica Modelli di superficie cellulare Punto nel tempo (episodio) Sangue |
nl-NL | Dutch (Netherlands) | cellen.CD27-/cellen.CD3+CD8+: |
zh-CN | Chinese (China) | 细胞.CD27-/细胞.CD3+CD8+: Synonyms: CD27细胞 CD3+CD8+细胞 CD3细胞 Leu2 Leu-2 Leu4; |
Example Units
Unit | Source |
---|---|
% | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=80701-6
LOINC Copyright
Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://