80704-0
CD27+CD45RA+ cells/CD3+CD4+ (T4 helper) cells in Blood
Active
Part Descriptions
LP200626-2 Cells.CD27+CD45RA+
CD27 and CD45RA are both lymphocyte cell surface markers that can be used to classify T-cells into various subsets. Expression of CD27 is characteristic of naive T-cells and some subsets of memory T-cells, while lack of CD27 is characteristic of effector T-cells. PMID: 19454729. CD45RA is characteristic of resting or naive T-cells. Cells expressing both CD27+CD45RA+ are undifferentiated (naive), CD27+CD45RA- T-cells are at an early stage of differentiation and exhibit characteristics of memory T cells, whereas CD27-CD45RA- T-cells are highly differentiated and have characteristics of both memory and effector T-cells. PMID: 12023349 PMID: 21788446
Source: Regenstrief LOINC
LP99724-4 Cells.CD3+CD4+
HIV infection decreases the number of CD3+ CD4+ lymphocytes (also called CD4 T cells or T4 helper cells) while increasing (momentarily) the numbers of CD3+CD8+ lymphocytes (called CD8 T lymphocytes or cytotoxic T cells). Thus the ratio of CD4/CD8 lymphocytes is decreased. These counts are used for prognostic purposes and to guide in the retroviral therapy. CDC has emphasized since 1997 that the number of CD3+ lymphocytes is necessary in addition to the number of CD4+ cells to reliably identify the T4 helper cells and the number of CD8+ cells. Laboratory reports that include only CD4 or only CD8 in their nomenclature are most likely really measuring CD3+CD4+ cells and CD3+CD8+ cells, respectively.
Source: Regenstrief Help
LP14443-3 CD4
Found on helper T-cells; weakly expressed on monocytes.
Associated with some mature T-cell neoplasms, including most cases of T-cell CLL/prolymphocytic leukemia, peripheral
T-cell lymphoma, adult T-cell leukemia/lymphoma and Sézary syndrome/mycosis fungoides
Source: Regenstrief LOINC
LP20086-2 CD45RA
Found on Naive helper T-cells, B-cells and Granulocytes
Associated with some T-cell lymphomas and some mature B-cell lymphomas
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Cells.CD27+CD45RA+/Cells.CD3+CD4+
- Property
- NFr
- Time
- Pt
- System
- Bld
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- CD27+CD45RA+ cells/CD3+CD4+ (T4 helper) cells in Blood
- Short Name
- CD27+CD45RA+ cells/CD3+CD4+ NFr Bld
- Display Name
- CD27+CD45RA+ cells/CD3+CD4+ (T4 helper) cells (Bld)
- Consumer Name Alpha Get Info
- CD27+CD45RA+ cells/CD3+CD4+ (T4 Helper) Cells, Blood
Basic Attributes
- Class
- CELLMARK
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.79 (NAM)
- Change Reason
- Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
- Order vs. Observation
- Observation
Member of these Panels
LOINC | Long Common Name |
---|---|
80720-6 | T-cell naive and memory and effector (CD27 and CD45RA) subsets panel - Blood |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Κύτταρα.CD27+CD45RA+/Κύτταρα.CD3+CD4+: Synonyms: CD27 CD3 CD4 CD45RA NFr Κύτταρα Κύτταρα.CD27 Κύτταρα.CD27- Κύτταρα.CD27+CD45RA- Κύτταρα.CD27+CD45RA+ Κύτταρα.CD27-CD45RA- Κύτταρα.CD27-CD45RA+ Κύτταρα.CD3 Κύτταρα.CD3+CD4+ Κύτταρα.CD3-CD4+ |
es-ES | Spanish (Spain) | Células CD27+CD45RA+/Células CD3+CD4+: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Cells.CD27 + CD45RA + / 100 Cells.CD3 + CD4 +: |
fr-FR | French (France) | CD27+CD45RA+/100 cellules CD3+CD4+: |
it-IT | Italian (Italy) | Cellule.CD27+CD45RA+/Cellule.CD3+CD4+: Synonyms: Cellule CD27 Cellule CD27- Cellule CD27+CD45RA- Cellule CD27+CD45RA+ Cellule CD27-CD45RA- Cellule CD27-CD45RA+ Cellule CD3 Cellule CD3+CD4+ Cellule CD3+CD4+ (T4 aiutanti) Cellule CD3-CD4+ Frazione numerica Modelli di superficie cellulare Punto nel tempo (episodio) Sangue |
nl-NL | Dutch (Netherlands) | cellen.CD27+CD45RA+/cellen.CD3+CD4+: |
zh-CN | Chinese (China) | 细胞.CD27+CD45RA+/细胞.CD3+CD4+: Synonyms: CD27细胞 CD3+CD4+细胞 CD3-CD4+细胞 CD3细胞 CD45RA L3T4 Leu18 Leu-18 Leu3 Leu-3 Leu4; |
Example Units
Unit | Source |
---|---|
% | Example UCUM Units |
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- CodeSystem lookup
- https:
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