Part Descriptions

LP207773-5   Sulfamethoxazole.free
Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic. It is most often used as part of a synergistic combination with trimethoprim in a 5:1 ratio in co-trimoxazole, which is also known as Bactrim or Septrin. It can be used as an alternative to amoxicillin -based antibiotics to treat sinusitis. Mechanism of action:Sulfonamides are structural anologs and competitive antagonists of para-aminobenzoic acid (PABA). They inhibit normal bacterial utilization of PABA for the synthesis of folic acid, an important metabolite in DNA synthesis. The effects seen are usually bacteriostatic in nature. Folic acid is not synthesized in humans, but is instead a dietary requirement. This allows for the selective toxicity to bacterial cells (or any cell dependent on synthesizing folic acid) over human cells. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Sulfamethoxazole (Wikipedia)

LP207910-3   free DRUG/TOX
The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug PMID: 6636249. For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Sulfamethoxazole.free:MCnc:Pt:Ser/Plas:Qn:
Long Common Name
Sulfamethoxazole free [Mass/volume] in Serum or Plasma
Short Name
Sulfamethoxazole free SerPl-mCnc
Display Name
Sulfamethoxazole free [Mass/Vol]
Consumer Name Alpha Get Info
Free sulfamethoxazole, Blood

Part Model Get Info

  • Component
    Sulfamethoxazole.free
    LP207773-5
    • Analyte
      Sulfamethoxazole.free
      LP207773-5
      • Component Numerator
        Sulfamethoxazole.free
        LP207773-5
        • Component Numerator Core
          Sulfamethoxazole.free
          LP207773-5
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    MCnc
    LP6827-2
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.56 (ADD)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Sulfamethoxazol volný:Hmotnostní koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
el-GRGreek (Greece)Σουλφαμεθοξαζόλη.ελεύθερη:MCnc:Pt:Ορός/Πλάσμα:Qn:
Synonyms: DRUG/TOX MCnc Pt Qn Ορός Ορός/Πλάσμα Πλάσμα Σουλφαμεθοξαζόλη Σουλφαμεθοξαζόλη.ελεύθερη
es-ESSpanish (Spain)Sulfometoxazol libre:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Sulfametoxazol libre:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
fr-FRFrench (France)Sulfaméthoxazole libre:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
it-ITItalian (Italy)Sulfametossazolo.libero:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma Sulfametossazolo libero
nl-NLDutch (Netherlands)sulfamethoxazol.vrij:massa/volume:moment:serum of plasma:kwantitatief:
zh-CNChinese (China)磺胺甲噁唑.游离型:质量浓度:时间点:血清/血浆:定量型:
Synonyms: SMX;SMZ;新明磺;新诺明;磺胺甲噁唑;磺胺甲基异噁唑;磺胺甲基异恶唑;磺胺甲异唑;磺胺甲恶唑 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 游离 磺胺甲噁唑(SMX、SMZ、新明磺、新诺明、磺胺甲基异噁唑、磺胺甲基异恶唑、磺胺甲异唑、磺胺甲恶唑).游离型(游离);游离型(游离)磺胺甲噁唑(SMX、SMZ、新明磺、新诺明、磺胺甲基异噁唑、磺胺甲基异恶唑、磺胺甲异唑、磺胺甲恶唑) 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆 非蛋白结合型 非蛋白质结合型

Example Units

UnitSource
mg/LExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=80974-9