8098-6

Thyroglobulin Ab [Units/volume] in Serum or Plasma

Active

Part Descriptions

LP14697-4 Thyroglobulin
Thyroglobulin (Tg) is a protein produced by and used entirely within the thyroid gland. Thyroglobulin is used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is stored in the thyroid in follicle cysts surrounded by colloid cells. Via a reaction with the enzyme thyroperoxidase, iodine is covalently bound to tyrosine residues in thyroglobulin molecules, forming monoiodotyrosine (MIT) and diiodotyrosine (DIT). Thyroxine is produced by linking two moieties of DIT. Combining one particle of MIT and one particle of DIT produces triiodothyronine. Proteases in lysosomes digest iodinated thyroglobulin, releasing T3 and T4. Thyroglobulin levels in the blood can be used as a tumor marker for certain kinds of thyroid cancer. Thyroglobulin levels in the blood can also be elevated in cases of Graves Disease. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Thyroglobulin (Wikipedia)

LP14697-4 Thyroglobulin
Thyroglobulin (Tg) is a glycoprotein homodimer produced by the thyroid gland. It is important in the synthesis of thyroxine and triiodothyronine, and is where the inactive forms of thyroid hormone and iodine are stored. Mutations in the Tg gene cause thyroid dyshormonogenesis resulting in goiter, and can be associated with moderate to severe congenital hypothyroidism. Polymorphisms in the Tg gene are associated with susceptibility to autoimmune thyroid diseases such as Graves disease or Hashimoto thyroiditis. [NCBI Gene ID:7038] Tg is an established tumor marker used in the diagnosis of differentiated thyroid carcinoma. PMID: 9543128 Source: Regenstrief LOINC

LP39996-1 Thyroglobulin Ab
Circulating immunoglobulins directed against thyroglobulin are commonly present in patients with autoimmune (Hashimoto) thyroiditis and, to a lesser extent, Graves disease. Thyroglobulin is a 660-kd protein precursor of thyroid hormones. Thyroglobulin antibodies are present in the sera of approximately 70% of patients with autoimmune thyroiditis. The principal use of the test is to confirm that a patient's diffuse goiter and/or hypothyroidism is due to autoimmune thyroiditis. The test may also help distinguish Graves disease from toxic nodular goiter. Although thyroglobulin antibodies are present less often than thyroid microsomal antibodies (eg, thyroid peroxidase antibodies, anti-TPO) in patients with autoimmune thyroid diseases, screening fro both immunoglobulins increases diagnostic sensitivity. Thyroglobulin antibodies may be detected in individuals without clinically significant thyroid disease. They do not define the patient's thyroid functional status. Source: Quest Diagnostics Inc., Thyroglobulin antibodies

LOINC Names Get Info

Fully-Specified Name: Thyroglobulin Ab:ACnc:Pt:Ser/Plas:Qn:
Long Common Name: Thyroglobulin Ab [Units/volume] in Serum or Plasma
Short Name: Thyroglob Ab SerPl-aCnc
Display Name: Thyroglobulin Ab Qn
Consumer Name Alpha Get Info: Thyroglobulin antibody, Blood

Part Model Get Info

Component
Thyroglobulin Ab
LP39996-1
- Analyte
  Thyroglobulin Ab
  LP39996-1
  - Component Numerator
    Thyroglobulin Ab
    LP39996-1
    - Component Numerator Core
      Thyroglobulin
      LP14697-4
    - Component Numerator Core Suffix
      Ab
      LP20667-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
ACnc
LP6773-8
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 1.0h(2)
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Both
Common Test Rank Get Info: 619

Member of these Panels

LOINC	Long Common Name
57780-9	Thyroglobulin and Thyroglobulin Ab panel - Serum or Plasma
87556-7	Thyroglobulin and thyroperoxidase Ab panel - Serum or Plasma

Member of these Groups Get Info

LOINC Group	Group Name
LG21864-0	Thyroglobulin Ab\|ACnc\|Pt\|ANYBldSerPl

Language Variants Get Info

Tag	Language	Translation
ar-JO	Arabic (Jordan)	أضداد الثيروغلوبيولين في المصل أو البلازما ( بتقنية الوحدات / الحجم )
cs-CZ	Czech (Czechia)	Tyreoglobulin Ab:Arbitrární koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
de-AT	German (Austria)	Synonyms: Thyreoglobulin-AK
de-DE	German (Germany)	Thyreoglobulin Ak:Arbiträre Konzentration:Zeitpunkt:Serum oder Plasma:Quantitativ: Synonyms: hTG
el-GR	Greek (Greece)	Θυρεοσφαιρίνη Αντίσωμα:ACnc:Pt:Ορός/Πλάσμα:Qn: Synonyms: ACnc Pt Qn SERO Αντίσωμα Θυρεοσφαιρίνη Ορός Ορός/Πλάσμα Πλάσμα
es-AR	Spanish (Argentina)	[anticuerpo anti - ] tiroglobulina [Ac]:concentración arbitraria:punto en el tiempo:suero:cuantitativo:
es-MX	Spanish (Mexico)	Tiroglobulina Ab:Concentración arbitraria:Punto temporal:Suero o Plasma:Cuantitativo:
es-ES	Spanish (Spain)	Tiroglobulina Anticuerpos:Concentración arbitraria:Punto temporal:Suero o Plasma:Qn: Synonyms: Cuantitativo
et-EE	Estonian (Estonia)	Türeoglobuliin antikehad:Acnc:Pt:S/P:Qn: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA	French (Canada)	Thyroglobuline, Ac:Concentration arbitraire:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR	French (France)	Thyroglobuline Ac:Arbitraire/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE	French (Belgium)	Thyroglobuline Ac:Concentration arbitraire:Temps ponctuel:Sérum/Plasma:Quantitatif: Synonyms: Anticorps hTG
it-IT	Italian (Italy)	Tireoglobulina Ab:ACnc:Pt:Siero/Plasma:Qn: Synonyms: anticorpo Concentrazione Arbitraria Plasma Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant
ko-KR	Korean (Korea, Republic Of)	갑상샘글로불린 항체:임의농도:검사시점:혈청:정량:
nl-NL	Dutch (Netherlands)	thyreoglobuline As:eenheid/volume:moment:serum of plasma:kwantitatief: Synonyms: antistof; antilichaam
pl-PL	Polish (Poland)	Tyreoglobulina Ab:stężenie w jednostkach umownych:punkt w czasie:surowica lub osocze:ilościowy:
pt-BR	Portuguese (Brazil)	Tireoglobulina Ac:ACnc:Pt:Soro:Qn: Synonyms: AntiTiroglob; TgAcs; Tiroglob; Thyglobulin; Thyroglbn; Tg; Arbitrary concentration; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Serology
ru-RU	Russian (Russian Federation)	Тиреоглобулин Ат:ПроизвКонц:ТчкВрм:Сыв/Плаз:Колич: Synonyms: Антитело Количественный Плазма Произвольная концентрация Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	Tiroglobulin Ab:SçKons:Zmlı:Ser/Plaz:Kant: Synonyms: Ak
uk-UA	Ukrainian (Ukraine)	Тиреоглобулін Антитіла:Довільна Концентрація:МоментЧасу:Сироватка/Плазма:Кількісно: Synonyms: ABS; Aby; Antby; Anti; Antibodies; Antibody; Antithyroglob; Arbitrary concentration; Autoantibodies; Autoantibody; Endocrine; Endocrinology; Hashimoto's thyroiditis; Pl; Plasma; Plsm; Point in time; QNT; Quan; Quant; Quantitative; Random; Serology; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR; Tg; TgAbs; Thyglobulin; Thyroglbn; Thyroglob; Tumor marker; UniversalLabOrders
zh-CN	Chinese (China)	甲状腺球蛋白抗体:任意型浓度:时间点:血清/血浆:定量型: Synonyms: Ab;自身抗体 TG;甲状球蛋白;甲状腺球朊;甲状腺球蛋白（Thyroglobulin，TG，Tg）;甲状腺球蛋白特异性 TgAbs 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度可用数量表示的;定量性;数值型;数量型;连续数值型标尺抗甲状腺球蛋白时刻;随机;随意;瞬间甲状腺球蛋白 Ab 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类血清或血浆

Example Units

Unit	Source
IU/mL	eCHN
units/mL	REGENSTRIEF
[IU]/mL	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.