8119-0

CD20 cells/cells in Blood

Active

Part Description

LP17751-6 Cells.CD20
B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein on the surface of all B-cells starting at the pro-B phase (CD45R+, CD117+) and increases in concentration until maturity. In humans CD20 is encoded by the MS4A1 gene. This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule that plays a role in the development and differentiation of B-cells into plasma cells. CD20 is the target of the monoclonal antibodies (mAb) rituximab, Ibritumomab tiuxetan, and tositumomab, that are active agents in the treatment of all B cell lymphomas and leukemias. The anti-CD20 mAB Ofatumumab (Genmab) was approved by FDA in Oct 2009 for Chronic lymphocytic leukemia. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, CD20

LOINC Names Get Info

Fully-Specified Name: Cells.CD20/Cells:NFr:Pt:Bld:Qn:
Long Common Name: CD20 cells/cells in Blood
Short Name: CD20 Cells NFr Bld
Display Name: CD20 cells/Cells (Bld)
Consumer Name Alpha Get Info: CD20 cells/cells, Blood

Part Model Get Info

Component
Cells.CD20/Cells
LP445063-3
- Analyte
  Cells.CD20/Cells
  LP445063-3
  - Component Numerator
    Cells.CD20
    LP17751-6
    - Component Numerator Core
      Cells.CD20
      LP17751-6
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    cells
    LP174115-8
    - Component Denominator Core
      cells
      LP174115-8
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
NFr
LP6838-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Bld
LP7057-5
- System Core
  Bld
  LP7057-5
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CELLMARK
Type: Laboratory
First Released: Version 1.0h(2)
Last Updated: Version 2.79 (NAM)
Change Reason: Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
Order vs. Observation: Observation
Common Test Rank Get Info: 3358

Member of these Panels

LOINC	Long Common Name
100994-3	B-cell CD19 and CD20 subsets panel - Blood by Flow cytometry (FC)
90414-4	B-cell phenotyping panel - Blood
90416-9	Lymphocyte subset and B-cell phenotyping panel - Blood

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Buňky.CD20/100 buněk:Početní podíl:Časový bod:Krev:Kvantitativní:
de-DE	German (Germany)	Zellen.CD20/Zellen:Numerische Fraktion:Zeitpunkt:Blut:Quantitativ:
el-GR	Greek (Greece)	Κύτταρα.CD20/κύτταρα:NFr:Pt:Αίμα:Qn: Synonyms: CD20 CELLMARK NFr Pt Qn Αίμα Κύτταρα Κύτταρα.CD20
es-AR	Spanish (Argentina)	células.células CD20/100 células:fracción de un número:punto en el tiempo:sangre:cuantitativo:
es-ES	Spanish (Spain)	Células CD20+/células:Fracción numérica:Punto temporal:Sangre:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Cells.CD20 / 100 células:Fracción numérica:Punto temporal:Sangre:Cuantitativo:
fr-FR	French (France)	CD20/cellules:Fraction de nombres:Ponctuel:Sang:Numérique:
fr-CA	French (Canada)	Cellules.CD20/Cellules:Fraction numérique:Temps ponctuel:Sang:Quantitatif:
it-IT	Italian (Italy)	Cellule.CD20/cellule:NFr:Pt:Sangue:Qn: Synonyms: Cellule CD20 Cellule.CD20+ Frazione numerica Modelli di superficie cellulare Punto nel tempo (episodio) Sangue
ko-KR	Korean (Korea, Republic Of)	세포.CD20/100 세포:숫자분획:검사시점:전혈:정량:
nl-NL	Dutch (Netherlands)	cellen.CD20/cellen:getalsfractie:moment:bloed:kwantitatief:
pl-PL	Polish (Poland)	Komórki.CD20/komórki:frakcja liczbowa:punkt w czasie:krew:ilościowy: Synonyms: Komórki CD20
pt-BR	Portuguese (Brazil)	Células.CD20/100 células:NFr:Pt:SgTotal:Qn: Synonyms: ; CD20 Cells; Cell; Cellularity; Leu-16; B-1; B1; Leu16; Bp35; Gated cells; Fr; Number fraction; Percent; Point in time; Random; Blood; WB; Whole blood; Quantitative; QNT; Quant; Quan; CELL MARKERS
ru-RU	Russian (Russian Federation)	Клетки.CD20/клетки:КолДоля:ТчкВрм:Кр:Колич: Synonyms: Количественный Количество отношение Кровь Точка во времени;Момент
tr-TR	Turkish (Turkey)	Hücreler.CD20/Hücreler:SayFr:Zmlı:Kan:Kant:
zh-CN	Chinese (China)	细胞.CD20/细胞:计数型分数:时间点:全血:定量型: Synonyms: B1;B-1;Bp35;Leu16;Leu-16 CD20 阳性细胞（多为 B 细胞） CD20细胞可用数量表示的;定量性;数值型;数量型;连续数值型标尺数量型分数;数量或计数型分数;数量型分数或计数型分数时刻;随机;随意;瞬间细胞含量;细胞性;细胞性质;细胞构成;细胞类细胞标志物血;血液

Example Units

Unit	Source
%	Example UCUM Units
%	REGENSTRIEF
%	eCHN

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CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=8119-0

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.