Version 2.78

Term Description

This panel contains terms to measure cyroglobulin immunoglobulins IgA, IgG, IgM, and cyroglobulin C3.
Source: Regenstrief LOINC

Part Description

LP207797-4   Cryoglobulin IgA & IgG & IgM & C3 panel
Cryoglobulins are immunoglobulins that precipitate as serum is cooled below core body temperatures. Cryoglobulinemia is characterized by the presence of cryoglobulins in the serum. Single-component cryoglobulins contain only one isotype of immunoglobulin or, in rare instances, a cryoprecipitable monoclonal immunoglobulin light chain. Mixed cryoglobulins are immune complexes made of two different types of immunoglobulin, usually an IgM antiglobulin and IgG antigen. The classification initially proposed (Brouet et al) describes simple cryoglobulins as type I, and sub-divides mixed cryoglobulins as type II, in which case the antiglobulin is typically monoclonal, and type III, in which the antiglobulin is polyclonal. Some disorders associated with Type I are: multiple myeloma, Waldenstrom's macroglobulinemia, and other lymphoproliferative diseases. Type II may be associated with: chronic hepatitis C virus infection, Sjogren's syndrome, Waldenstrom's macroglobulinemia, chronic lymphocytic leukemia, non-Hodgkins' lymphoma, autoimmune diseases. Type III may be associated with: chronic infections, viral (EBV, CMV, HIV, hepatitis viruses), bacterial (SBE, leprosy, spirochetal), fungal, parasitic, autoimmune diseases, systemic lupus erythematosus (SLE), rheumatoid arthritis, inflammatory bowel diseases, and biliary cirrhosis. Screening for complement levels is done by quantitating antigenic levels of C3 and C4 and determining total hemolytic complement (CH50). Very low or undetectable levels of C4 with normal or relatively normal levels of C3 are often seen in type II cryoglobulinemia, and may suggest this diagnosis or a need for further workup for HCV infection. Low complement levels may also be seen in association with type II cryoglobulinemia complicating Sjogren's syndrome or with type III cryoglobulinemia in patients with rheumatoid vasculitis or SLE. Source: Regenstrief LOINC, PMID: 10050784

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
81205-7 Cryoglobulin IgA and IgG and IgM and C3 panel - Serum
Indent55848-6 Cryoglobulin.IgG [Presence] in Serum R
Indent81311-3 Cryoglobulin.IgA [Presence] in Serum R
Indent81312-1 Cryoglobulin.IgM [Presence] in Serum R
Indent81313-9 Cryoglobulin.complement C3 [Presence] in Serum O
Indent49260-3 Cryoglobulin IgA and IgG and IgM [Interpretation] in Serum Narrative O

Fully-Specified Name

Component
Cryoglobulin IgA & IgG & IgM & C3 panel
Property
-
Time
Pt
System
Ser
Scale
-
Method

Additional Names

Short Name
Cryo IgA + IgG + IgM + C3 Pnl Ser
Display Name
Cryoglobulin IgA and IgG and IgM and C3 panel (S)
Consumer Name Alpha Get Info
Cryoglobulin IgA and IgG and IgM and C3 Panel, Blood

Basic Attributes

Class
PANEL.CHEM
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.56
Order vs. Observation
Order
Panel Type
Panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Panel de crioglobulinas IgG, IgA e IgM:Propiedades mixtas (sólo paneles):Punto temporal:Suero:-:
es-MX Spanish (Mexico) Panel de crioglobulina IgA e IgG e IgM y C3:-:Punto temporal:Suero:-:
fr-FR French (France) Cryoglobulines IgA et IgG et IgM et C3 panel:-:Ponctuel:Sérum:-:
it-IT Italian (Italy) Crioglobulina IgA & IgG & IgM & C3 panel:-:Pt:Siero:-:
Synonyms: Chimica IgA & IgG & IgM crioglobulina Panel Crioglobulina IgA, IgG,IgM e C3 Punto nel tempo (episodio) Set di prescrizione chimica Siero
nl-NL Dutch (Netherlands) cryoglobuline IgA & IgG & IgM & C3 panel:-:moment:serum:-:
pl-PL Polish (Poland) Krioglobulina IgA & IgG & IgM & C3 panel:-:punkt w czasie:surowica:-:
Synonyms: IgG IgM Immunoglobulina A Kreatynina przed podaniem 2 mg deksametazonu przez 2,5 dnia wysokiej dawki co 6h Krioglobulina IgA Krioglobulina IgA, IgG, IgM, C3 Panel krioglobulin IgA i IgG i IgM i C3
zh-CN Chinese (China) 冷球蛋白 IgA 与 IgG 与 IgM 与 C3 组套:-:时间点:血清:-:
Synonyms: Cryo;冷凝蛋白质;冷沉淀;冷沉淀物;冷沉淀球蛋白;冷沉球蛋白 免疫球蛋白 A 免疫球蛋白 G 免疫球蛋白 M 冷球蛋白（冷凝蛋白质、冷沉淀、冷沉淀物、冷沉淀球蛋白、冷沉球蛋白） IgA 与 IgG 与 IgM 与 C3 组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目） 冷球蛋白（冷凝蛋白质、冷沉淀、冷沉淀物、冷沉淀球蛋白、冷沉球蛋白）.IgA 冷球蛋白（冷凝蛋白质、冷沉淀、冷沉淀物、冷沉淀球蛋白、冷沉球蛋白）IgA 与 IgG 与 IgM 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 医嘱套餐 医嘱套餐类 医嘱套餐组 医嘱组 医嘱组.化学试验;化学组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）;化学医嘱组类;医嘱组.化学;医嘱组.化学检验项目;医嘱组类.化学;医嘱组类.化学检验项目;医嘱组类.化学试验;实验室医嘱组类.化学;实验室医嘱组类.化学检验项目;实验室医嘱组类.化学试验 医嘱组合 医嘱组合类 医嘱组套 医嘱组套类 医嘱组类 多重;多重型;多重标尺类型;多重精度类型 套餐 套餐医嘱 套餐医嘱组 套餐医嘱组类 实验室医嘱套餐 实验室医嘱套餐类 实验室医嘱组 实验室医嘱组合类 实验室医嘱组套 实验室医嘱组套类 实验室套餐医嘱组 实验室套餐医嘱组类 实验室检验项目医嘱组合类 实验室检验项目组合类 时刻;随机;随意;瞬间 检验医嘱组合类 检验项目医嘱组合类 检验项目组合类 组 组合 组合医嘱 组合类 组套

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=81205-7
Questionnaire definition
https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/81205-7