Version 2.78

Part Description

LP212222-6   Microsatellite instability marker panel
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor. Source: Regenstrief LOINC

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
81711-4 Microsatellite instability marker panel - Cancer specimen
Indent81696-7 Microsatellite instability markers assessed [#] in Cancer specimen {#}
Indent81697-5 Microsatellite instability marker BAT25 in Cancer specimen Qualitative
Indent81698-3 Microsatellite instability marker BAT26 in Cancer specimen Qualitative
Indent81699-1 Microsatellite instability marker NR21 in Cancer specimen Qualitative
Indent81700-7 Microsatellite instability marker NR24 in Cancer specimen Qualitative
Indent81701-5 Microsatellite instability marker MONO27 in Cancer specimen Qualitative
Indent81702-3 Microsatellite instability marker D2S123 in Cancer specimen Qualitative
Indent81703-1 Microsatellite instability marker D5S346 in Cancer specimen Qualitative
Indent81704-9 Microsatellite instability marker D17S250 in Cancer specimen Qualitative
Indent81709-8 Microsatellite markers exhibiting instability [#] in Cancer specimen {#}
Indent81708-0 Microsatellite markers exhibiting instability/Microsatellite instability markers assessed in Cancer specimen %
Indent81695-9 Microsatellite instability [Interpretation] in Cancer specimen Qualitative

Fully-Specified Name

Component
Microsatellite instability marker panel
Property
-
Time
Pt
System
Cancer specimen
Scale
-
Method

Additional Names

Short Name
MSI mark Pnl Ca spec
Display Name
Microsatellite instability marker panel (Cancer specimen)
Consumer Name Alpha Get Info
Microsatellite instability marker panel, Cancer specimen

Basic Attributes

Class
PANEL.PATH
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.61
Change Reason
Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation
Order
Panel Type
Panel

Member of these Panels

LOINC Long Common Name
85905-8 Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Panel de marcadores de inestabilidad de microsatélites:Propiedades mixtas (sólo paneles):Punto temporal:Muestra de cancer:-:
es-MX Spanish (Mexico) Panel marcador de inestabilidad de microsatélites:-:Punto temporal:Espécimen de cáncer:-:
it-IT Italian (Italy) Marcatore di instabilità dei microsatelliti, panel:-:Pt:Campione tumore:-:
Synonyms: Campione di tumore Instabilità dei microsatelliti Neoplasia maligna Panel Marcatore di instabilità dei microsatelliti Patologia Punto nel tempo (episodio) Set di prescrizione per patologia
zh-CN Chinese (China) 微卫星不稳定性标记组套:-:时间点:癌标本:-:
Synonyms: MSI 供检查用的材料;待检物;待试验物;样品;样本;试料;试样 医嘱套餐 医嘱套餐类 医嘱套餐组 医嘱组 医嘱组.病理学;病理学组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目） 医嘱组合 医嘱组合类 医嘱组套 医嘱组套类 医嘱组类 受检物 多重;多重型;多重标尺类型;多重精度类型 套餐 套餐医嘱 套餐医嘱组 套餐医嘱组类 实验室医嘱套餐 实验室医嘱套餐类 实验室医嘱组 实验室医嘱组合类 实验室医嘱组套 实验室医嘱组套类 实验室套餐医嘱组 实验室套餐医嘱组类 实验室检验项目医嘱组合类 实验室检验项目组合类 微卫星不稳定性（MSI）标记（标记物、标志、标志物）组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目） 时刻;随机;随意;瞬间 样品 样本 检验医嘱组合类 检验项目医嘱组合类 检验项目组合类 癌 癌（癌症、癌变）标本（样本、样品、试样） 组 组合 组合医嘱 组合类 组套 试样

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=81711-4
Questionnaire definition
https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/81711-4