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Term Description

This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.

Part Description

LP37936-9   DNA double strand Ab
Antibodies to DNA, either single- or double-stranded, are found primarily in systemic lupus erythematosus, and are important, but not necessary or sufficient for diagnosing that condition. Such antibodies are present in 80% to 90% of SLE cases. They are also present in smaller fractions of patients with other rheumatic disorders, and in chronic active hepatitis, infectious mononucleosis, and biliary cirrhosis Source: LOINC partner 1

LOINC Names Get Info

Fully-Specified Name
DNA double strand Ab:PrThr:Pt:Ser:Ord:Line blot
Long Common Name
DNA double strand Ab [Presence] in Serum by Line blot
Short Name
dsDNA Ab Ser Ql Line blot
Display Name
DNA double strand Ab Line blot Ql (S)
Consumer Name Alpha Get Info
DNA double strand antibody, Blood

Part Model Get Info

  • Component
    DNA double strand Ab
    LP37936-9
    • Analyte
      DNA double strand Ab
      LP37936-9
      • Component Numerator
        DNA double strand Ab
        LP37936-9
        • Component Numerator Core
          DNA double strand
          LP15012-5
        • Component Numerator Core Suffix
          Ab
          LP20667-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Line blot
    LP266806-1

Example Answer List: LL360-9

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)LA6577-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.64 (MAJ)
Change Reason
This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.
Order vs. Observation
Both

Member of these Groups Get Info

LOINC GroupGroup Name
LG707-6DNA double strand Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)DNA dvouřetězcová Ab:Přítomnost nebo práh:Časový bod:Sérum:Ordinální:Line blot
de-DEGerman (Germany)DNA-Doppelstrang Ak:Nachweis oder Schwellenwert:Zeitpunkt:Serum:Ordinal:Line-Blot
Synonyms: dsDNA
el-GRGreek (Greece)Δίκλωνο DNA Αντίσωμα:PrThr:Pt:Ορός:Ord:Γραμμή κηλίδωσης
Synonyms: DNA Ord PrThr Pt SERO Αντίσωμα Γραμμή κηλίδωσης Δίκλωνο DNA Ορός
es-ESSpanish (Spain)ADN de doble cadena Anticuerpos:PrThr:Punto temporal:Suero:Ord:Line blot
es-MXSpanish (Mexico)ADN de doble hebra Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Mancha de línea
fr-CAFrench (Canada)ADN double brin, Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoessai sur bandelette
fr-FRFrench (France)ADN double brin Ac:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Blot en ligne
it-ITItalian (Italy)DNA doppia elica Ab:PrThr:Pt:Siero:Ord:Line blot
Synonyms: anticorpo DS DNA Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NLDutch (Netherlands)DNA dubbelstrengs As:aanwezigheid:moment:serum:ordinaal:lijnblot
Synonyms: antistof; antilichaam
pl-PLPolish (Poland)Podwójna nić DNA Ab:granica wykrywalności:punkt w czasie:surowica:uporządkowany:line blot
Synonyms: dsDNA Kwas deoksyrybonukleinowy Przeciwciała do dsDNA
zh-CNChinese (China)双链 DNA 抗体:存在情况或阈值:时间点:血清:序数型:线点印迹法
Synonyms: Ab;自身抗体 DNA 双链 Ab DNA 双链;dsDNA;去氧核糖核酸双链;双链去氧核糖核酸;双链脱氧核糖核酸;天然 DNA;脱氧核糖核酸双链 DNA 双链抗体 ds dsDNA Ab dsDNA 抗体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA） 去氧核糖核酸双链 Ab 去氧核糖核酸双链抗体 双股 双链 DNA Ab 双链（Double strand，ds） 双链去氧核糖核酸 Ab 双链去氧核糖核酸抗体 双链脱氧核糖核酸 Ab 双链脱氧核糖核酸抗体 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 线点杂交技术;线点杂交法;线条状印迹法 股 脱氧核糖核酸双链 Ab 脱氧核糖核酸双链抗体 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=81716-3