81719-7

Deprecated Ganglioside GM1 IgM Ab [Presence] in Serum by Immunoblot

Deprecated

Status Information

Status: DEPRECATED
Reason: Duplicate
Comment: Created with Method "IB" but upon further review found to be "IA", which makes this term a duplicate.

Map-To	Long Common Name	Mapping Guidance
63247-1	Ganglioside GM1 IgM Ab [Presence] in Serum by Immunoassay

Part Descriptions

LP36423-9 Ganglioside GM1
Gangliosides are a family of molecules that are present throughout the body but especially prevalent in cells of the nervous system. Specific gangliosides are named for the carbohydrate sequence they contain and have a unique distribution within the nervous system. The oligosaccharide groups on gangliosides act as cell surface markers that play a role in cellular recognition and cell-to-cell communication, and they also act as specific receptors for certain pituitary glycoprotein hormones and certain bacterial protein toxins such as cholera toxin.
Anti-ganglioside antibodies, primarily IgG, are present in the sera from approximately 60% of patients with Guillain-Barré syndrome (GBS), and antibodies against different gangliosides are associated with different forms of GBS.
1. Antibodies against GD1a/GD1b and GD1b/GT1b complexes have been found in patients with more severe GBS requiring mechanical ventilation;
2. Antibodies against GM1 or those against GalNAc-GD1a have been associated with acute motor axonal neuropathy;
3. Anti-GQ1b antibodies are specifically associated with a variant of GBS called Fisher syndrome, which is characterized by ophthalmoplegia and ataxia.
Detection of specific markers early in the course of GBS may help guide the plan of care. PMID: 21214559 Source: Regenstrief LOINC, PMID: 2121455

LP222219-0 Ganglioside
A ganglioside molecule consists of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acid residues linked to the sugar chain. Molecules with one sialic acid residue are called monosialogangliosides (GM), those with two are called disialogangliosides (GD), and those with three are trisialogangliosides (GT). Gangliosides without any sialic acid residues are called asialogangliosides, while those that do not have a ceramide N-acyl group are called lysogangliosides. The number that typically is included at the end of the name indicates the order in which the molecule was discovered. For example, GM2 is a ganglioside with one sialic acid residue that was the second GM to be identified. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Ganglioside GM1 Ab.IgM:PrThr:Pt:Ser:Ord:IB
Long Common Name: Deprecated Ganglioside GM1 IgM Ab [Presence] in Serum by Immunoblot
Short Name: Deprecated GM1 Gangl IgM Ser Ql IB
Display Name: Ganglioside GM1 IgM IB Ql (S)
Consumer Name Alpha Get Info: Ganglioside GM1 IgM antibody, Blood

Part Model Get Info

Component
Ganglioside GM1 Ab.IgM
LP38227-2
- Analyte
  Ganglioside GM1 Ab.IgM
  LP38227-2
  - Component Numerator
    Ganglioside GM1 Ab.IgM
    LP38227-2
    - Component Numerator Core
      Ganglioside GM1
      LP36423-9
    - Component Numerator Core Suffix
      Ab.IgM
      LP32403-5
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Ord
LP7751-3
Method
IB
LP6320-8

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.58 (DEL)
Order vs. Observation: Both

Member of these Groups Get Info

LOINC Group	Group Name
LG17828-1	Ganglioside GM1 Ab.IgM\|PrThr\|Pt\|ANYBldSerPl

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Gangliosid GM1 IgM:Přítomnost nebo práh:Časový bod:Sérum:Ordinální:Imunoblot
el-GR	Greek (Greece)	Γαγγλιοσίδη GM1 Αντισώματα IgM:PrThr:Pt:Ορός:Ord:IB Synonyms: IB Ord PrThr Pt SERO Ανοσοσφαιρίνη M Αντίσωμα Αντισώματα IgM Γαγγλιοσίδη Γαγγλιοσίδη GM1 Ορός
es-ES	Spanish (Spain)	Gangliósido GM1 IgM:PrThr:Punto temporal:Suero:Ord:Inmunoblot (IB)
es-MX	Spanish (Mexico)	Gangliósido GM1 Ab.IgM:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunotransferencia
et-EE	Estonian (Estonia)	Gangliosiid GM1 antikehad.IgM:PrThr:Pt:S:Ord:IB Synonyms: Immuunglobuliin M Järgarvuline Juhuslik Seerum
fr-CA	French (Canada)	Ganglioside GM1, IgM:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoblot
fr-BE	French (Belgium)	Ganglioside GM1 Anticorps. IgM:PrThr:Temps ponctuel:Sérum:Ordinal:Immunoblot Synonyms: Anticorps
fr-FR	French (France)	Ganglioside GM1 Ac IgM:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunoblot
it-IT	Italian (Italy)	Ganglioside GM1 Ab.IgM:PrThr:Pt:Siero:Ord:IB Synonyms: Anticorpi IgM anticorpo Immunoblot (IB) Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL	Dutch (Netherlands)	ganglioside GM1 As.IgM:aanwezigheid:moment:serum:ordinaal:immunoblotting Synonyms: antistof; antilichaam IB
pl-PL	Polish (Poland)	Gangliozyd GM1 Ab.IgM:granica wykrywalności:punkt w czasie:surowica:uporządkowany:immunoblotting Synonyms: IgM Przeciwciała do gangliozydu GM1 Przeciwciała IgM do gangliozydu GM1
ru-RU	Russian (Russian Federation)	Ганглиозид GM1 Ат.IgM:PrThr:ТчкВрм:Сыв:Пор:ИБ Synonyms: Антитело Иммуноблот (ИБ) Порядковый Сыворотка Точка во времени;Момент
tr-TR	Turkish (Turkey)	Gangliozid GM1 Ab.IgM:MevcEşik:Zmlı:Ser:Srl:IB Synonyms: Ak Ak.IgM Mevcut
zh-CN	Chinese (China)	神经节苷脂 GM1 抗体.IgM:存在情况或阈值:时间点:血清:序数型:免疫印迹法 Synonyms: Ab.IgM;IgM;抗体 IgM Ab;自身抗体 GM1;神经节糖苷 GM1 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫印迹;西部印迹法;Immunoblot;immunoblotting;IB 免疫球蛋白 M 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间神经节糖苷神经节苷脂 GM1 Ab 神经节苷脂 GM1 Ab.IgM 神经节苷脂 GM1 IgM 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.