Version 2.78

Term Description

This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.
Source: Regenstrief LOINC

Part Description

LP102300-3   PM-SCL-100
Anti-PM-SCL antibodies (75kD and 100 kD) are anti-nuclear antibodies present in patients with polymyositis (PM), systemic sclerosis (SSc), and PM/SSc overlap syndromes. The PM-SCL antibodies are directed mainly against the 75kD antigen. Source: Regenstrief LOINC, PMID: 19220911

Fully-Specified Name

Component
PM-SCL-100 Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
Line blot

Additional Names

Short Name
PM/SCL-100 Ab Ser Ql Line blot
Display Name
PM-SCL-100 Ab Line blot Ql (S)
Consumer Name Alpha Get Info
PM-SCL-100 antibody, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.73
Change Reason
This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.
Order vs. Observation
Both
Common Test Rank Get Info
3391

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: PM-Scl-100-AK ql.
es-ES Spanish (Spain) PM-SCL-100 Anticuerpos:PrThr:Punto temporal:Suero:Ord:Line blot
es-MX Spanish (Mexico) PM-SCL-100 Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Mancha de línea
fr-FR French (France) PM-SCL-100 anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Blot en ligne
it-IT Italian (Italy) PM-SCL-100 Ab:PrThr:Pt:Siero:Ord:Line blot
Synonyms: anticorpo Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) PM-SCL-100 As:aanwezigheid:moment:serum:ordinaal:lijnblot
Synonyms: antistof; antilichaam
zh-CN Chinese (China) PM-SCL-100 抗体:存在情况或阈值:时间点:血清:序数型:线点印迹法
Synonyms: Ab;自身抗体 PM-SCL extractable nuclear 100kD;PM-Scl100;PM-SCL 可提取性核 100kD;Scleromyositis;硬化性肌炎;polymyositis;PM;多发性肌炎;systemic sclerosis;系统性硬化病;硬皮病;SSc;PM/Scl overlap syndrome;系统性硬化病与多发性肌炎重叠综合征;autoimmune disease;自身免疫性疾病 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 皮硬化症 硬皮病 硬皮病（Scleroderma，SCL） 硬皮症 线点杂交技术;线点杂交法;线条状印迹法 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=81732-0