81804-7

5-Alpha tetrahydrocortisol/Creatinine [Molar ratio] in Urine

Active

Part Descriptions

LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

LP97520-8 5-Alpha tetrahydrocortisol
5 alpha-Tetrahydrocortisol is a normal human metabolite. However its increased ratio (5alpha-Tetrahydrocortisol + Tetrahydrocortisol) over Tetrahydrocortisone in urine is the biochemical marker for the syndrome of apparent mineralocorticoid excess (AME). AME is a heritable form of hypertension due to an inborn error of cortisol metabolism and is characterized by hypokalemia and low renin levels despite subnormal or normal levels of aldosterone and other known mineralocorticoids. The syndrome is attributable to congenital deficiency of the enzyme 11 beta-hydroxydehydrogenase (11 beta-HSD), which converts cortisol to biologically inactive cortisone. This results in a prolonged half-life of Cortisol, which acts at the kidney level as a potent mineralocorticoid. PMID: 8732999 Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, 5-Alpha tetrahydrocortisol

LOINC Names Get Info

Fully-Specified Name: 5-Alpha tetrahydrocortisol/Creatinine:SRto:Pt:Urine:Qn:
Long Common Name: 5-Alpha tetrahydrocortisol/Creatinine [Molar ratio] in Urine
Short Name: 5a-4HC/creat Ur-sRto
Display Name: 5-Alpha tetrahydrocortisol/Creatinine (U) [Molar ratio]
Consumer Name Alpha Get Info: 5-Alpha tetrahydrocortisol/Creatinine, Urine

Part Model Get Info

Component
5-Alpha tetrahydrocortisol/Creatinine
LP450605-3
- Analyte
  5-Alpha tetrahydrocortisol/Creatinine
  LP450605-3
  - Component Numerator
    5-Alpha tetrahydrocortisol
    LP97520-8
    - Component Numerator Core
      5-Alpha tetrahydrocortisol
      LP97520-8
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    Creatinine
    LP32035-5
    - Component Denominator Core
      Creatinine
      LP32035-5
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
SRto
LP6868-6
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Urine
LP7681-2
- System Core
  Urine
  LP7681-2
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.56
Last Updated: Version 2.82 (NAM)
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
73886-4	Steroid fractions panel - Urine

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Allo-tetrahydrokortizol/kreatinin:Látkový poměr:Časový bod:Moč:Kvantitativní:
el-GR	Greek (Greece)	5-α-τετραϋδροκορτιζόλη/Κρεατινίνη:SRto:Pt:Ούρα:Qn: Synonyms: 5-α-τετραϋδροκορτιζόλη CHEM Pt Qn SRto Κρεατινίνη Ούρα Τετραϋδροκορτιζόλη
es-ES	Spanish (Spain)	5-Alfa tetrahidrocortisol/Creatinina:Relacion de Sustancia:Punto temporal:Orina:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Alo-tetrahidrocortisol / Creatinina:Proporción de sustancia:Punto temporal:Orina:Cuantitativo:
fr-CA	French (Canada)	5-alpha tétrahydrocortisol/Créatinine:Ratio de substance:Temps ponctuel:Urine:Quantitatif:
fr-FR	French (France)	5-alpha tétrahydrocortisol/créatinine:Moles ratio:Ponctuel:Urine:Numérique:
fr-BE	French (Belgium)	5-Alpha tétrahydrocortisol/Créatinine:Ratio de substance:Temps ponctuel:Urine:Quantitatif:
it-IT	Italian (Italy)	5-Alfa tetraidrocortisolo/Creatinina:Srto:Pt:Urine:Qn: Synonyms: Chimica Punto nel tempo (episodio) Rapporto di sostanza
nl-NL	Dutch (Netherlands)	5-alfa-tetrahydrocortisol/creatinine:molaire verhouding:moment:urine:kwantitatief: Synonyms: kreatinine
pl-PL	Polish (Poland)	5-Alfa tetrahydrokortyzol/kreatynina:współczynnik molowy:punkt w czasie:mocz:ilościowy:
ru-RU	Russian (Russian Federation)	5-Альфа тетрагидрокортизол/Креатинин:МольОтн:ТчкВрм:Моча:Колич: Synonyms: Количественный Мольная доля;Молярная доля;Отношение концентраций Точка во времени;Момент
tr-TR	Turkish (Turkey)	5-Alfa tetrahidrokortizol/Kreatinin:SOrn:Zmlı:İdrar:Kant: Synonyms: SubsOranı
zh-CN	Chinese (China)	5-Alpha 四氢皮质醇/肌酐:物质的量比率:时间点:尿液:定量型: Synonyms: 5 Alpha-四氢皮质甾醇 5 Alpha-四氢皮醇 5-A 四氢皮质醇;5-α 四氢皮质醇;5-alpha（α、A）四氢皮质醇（THC、THF、四氢皮质甾醇、四氢皮醇） 5α-四氢皮质甾醇 5α-四氢皮质醇 5α-四氢皮醇 CR;Creat;肌氨酸酐;肌酸内酰胺;肌酸酐 THC;THF;四氢皮质甾醇;四氢皮醇 UCr α 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺尿;小便;下泉尿液肌酐尿液肌酸酐尿肌酸酐时刻;随机;随意;瞬间物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值肌酸内酰胺阿尔法

Example Units

Unit	Source
umol/mol{creat}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.