Term Description

This assay detects the presence of nucleic acid sequences from the Streptococcus pneumoniae DNA in cerebrospinal fluid (CSF) using PCR and non-probe based detection methods, such as melt curve analysis. This term was created for, but is not limited in use to, BioFire's FilmArray Meningitis/Encephalitis Panel, which is intended for the detection and identification of nucleic acids from multiple bacteria, viruses, and yeast directly from CSF obtained via lumbar puncture from individuals with signs and/or symptoms of meningitis and/or encephalitis.

Part Description

LP14410-2   Streptococcus pneumoniae
Streptococcus pneumoniae are gram-positive cocci that are nonmotile and nonsporulating and usually require complex culture media. Older streptococcal cultures, beyond the most active growth period (the logarithmic phase), sometimes lose their gram-positive staining characteristics. S. pneumoniae are part of the normal respiratory tract flora. Disease usually results due to the acquisition of a new strain following a change in the normal flora, often due to a preceding virus. S. pneumonaie causes otitis media, sinusitis and pneumonia in the middle ear, sinuses or lungs, respectively. Meningitis can occur by bloodstream invasion from the lungs or by extension of otitis media or sinusitis to the meninges. Bacteremia can result in osteomyelitis (infection of bones) or arthritis (of joints). Most bacterial pneumonia occurring after the neonatal period is caused by S. pneumoniae. Pneumococcal pneumonia is seen most commonly in elderly or immunosuppressed individuals. In the United States, it is most prevalent in winter. Diagnosis is usually based on a sputum Gram stain and culture although blood or cerebrospinal fluid may be cultured. While penicillin has been the standard treatment, some strains have proven resistant to penicillin and multiple antibiotics. A vaccine exists. [NCBI Books:NBK7611] Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Streptococcus pneumoniae DNA:PrThr:Pt:CSF:Ord:Non-probe.amp.tar
Long Common Name
Streptococcus pneumoniae DNA [Presence] in Cerebrospinal Fluid by NAA with non-probe detection
Short Name
S pneum DNA CSF Ql NAA+n-prb
Display Name
S. pneumoniae DNA NAA+non-probe Ql (CSF)
Consumer Name Alpha Get Info
Streptococcus pneumoniae, Spinal fluid

Part Model Get Info

  • Component
    Streptococcus pneumoniae DNA
    LP64750-0
    • Analyte
      Streptococcus pneumoniae DNA
      LP64750-0
      • Component Numerator
        Streptococcus pneumoniae DNA
        LP64750-0
        • Component Numerator Core
          Streptococcus pneumoniae
          LP14410-2
        • Component Numerator Core Suffix
          DNA
          LP32416-7
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    CSF
    LP7156-5
    • System Core
      CSF
      LP7156-5
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Non-probe.amp.tar
    LP208998-7

Example Answer List: LL744-4

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
DetectedLA11882-0
Not detectedLA11883-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.83 (MIN)
Order vs. Observation
Both
Common Test Rank Get Info
2525

Member of these Panels

LOINCLong Common Name
82180-1Meningitis+Encephalitis pathogens panel - Cerebrospinal Fluid by NAA with non-probe detection

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Streptococcus pneumoniae DNA:Přítomnost nebo práh:Časový bod:Mozkomíšní mok:Ordinální:Amplifikace nukleových kyselin s detekcí bez sondy
de-ATGerman (Austria)Synonyms: Streptococcus pneumoniae DNA /Liquor PCR
de-DEGerman (Germany)Streptococcus pneumoniae DNA:Nachweis oder Schwellenwert:Zeitpunkt:Liquor:Ordinal:Zielfragmentamplifikation mit Detektion ohne Sonde
Synonyms: Zerebrospinalflüssigkeit
el-GRGreek (Greece)Streptococcus pneumoniae (Στρεπτόκοκκος πνευμονίας) DNA:PrThr:Pt:ΕΝΥ:Ord:Χωρίς ανιχνευτή.ενίσχυση.στόχου
Synonyms: DNA MICRO Ord PrThr Pt Streptococcus pneumoniae (Στρεπτόκοκκος πνευμονίας) Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου ΕΝΥ Χωρίς ανιχνευτή.ενίσχυση.στόχου
es-ESSpanish (Spain)Streptococcus pneumoniae ADN:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Amplificación del objetivo no basado en sonda
es-MXSpanish (Mexico)ADN de Streptococo pneumoniae:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Amplificación de ácidos nucleicos con detección sin sonda
fr-CAFrench (Canada)Streptococcus pneumoniae, ADN:Présence-Seuil:Temps ponctuel:LCR:Ordinal:Non-sonde.amplification de cible
fr-FRFrench (France)Streptococcus pneumoniae ADN:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Non-PCR amplification de cible
it-ITItalian (Italy)Streptococcus pneumoniae DNA:PrThr:Pt:LCS:Ord:Non-sonda.amp.tar
Synonyms: Amplificazione target non basata su sonda Liquido cerebrospinale Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
pl-PLPolish (Poland)Streptococcus pneumoniae DNA:granica wykrywalności:punkt w czasie:płyn mózgowo-rdzeniowy:uporządkowany:bez sondy.amplifikacja.cel
Synonyms: amplifikacja kwasu nukleinowego z detekcją bez użycia sondy amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy Dwoinka zapalenia płuc;pneumokok Kwas deoksyrybonukleinowy
zh-CNChinese (China)肺炎链球菌 DNA:存在情况或阈值:时间点:脑脊液:序数型:非探针法.基因扩增.靶向
Synonyms: CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 借助靶向扩增的非探针方法;借助靶向扩增的非探针法;非探针法.扩增.靶向 去氧核糖核酸;脱氧核糖核酸 去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸(Deoxyribonucleic acid,DNA) 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 扩增型 扩增性 时刻;随机;随意;瞬间 球菌肺炎;肺双;肺炎双球菌;肺炎球菌;肺链;链球菌肺炎 经过扩增的 脊液 脊髓液 脑脊液(Cerebral spinal fluid,CSF) 脑脊髓液 脱氧核糖核酸探针

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=82187-6