Version 2.76

Term Description

This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.
Source: Regenstrief LOINC

Part Description

LP14905-1   Sulfatide
Anti-sulfatide autoantibodies, also known as anti-GalS, have been associated with a variety of nervous system disorders, including IgM paraproteinaemia with associated demyelinating neuropathy, sensory impairment, and inflammatory demyelinating polyneuropathy (IDPN). Studies have shown the presence of GalS on the external surface of the myelin sheath, which suggests that anti-GalS auto-antibodies can induce immune demyelination and may play a role in the pathogenesis of motor neuropathies such as Guillain-Barre syndrome (GBS), and in fact, over 60% of GBS patients have been found to have anti-GalS antibodies. Some data show that patients presenting with high titer of anti-GalS antibodies could benefit from early treatment with plasmapheresis and/or intravenous immunoglobulin. PMID: 10762412 ] Source: Regenstrief LOINC, PMID: 10762412

Fully-Specified Name

Sulfatide Ab.IgM
Line blot

Additional Names

Short Name
Sulfatide IgM Ser Ql Line blot
Display Name
Sulfatide IgM Line blot Ql (S)
Consumer Name Alpha Get Info
Sulfatide IgM antibody, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

First Released
Version 2.58
Last Updated
Version 2.66
Change Reason
This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.
Order vs. Observation

Member of these Groups Get Info

LOINC Group Group Name
LG17829-9 Sulfatide Ab.IgM|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Sulfátido IgM:PrThr:Punto temporal:Suero:Ord:Line blot
es-MX Spanish (Mexico) Ab.IgM de sulfatida:Presencia o umbral:Punto temporal:Suero:Ordinal:Mancha de línea
fr-CA French (Canada) Sulfatide , IgM:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoessai sur bandelette
fr-FR French (France) Sulfatide anticorps IgM:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Blot en ligne
it-IT Italian (Italy) Sulfatide Ab.IgM:PrThr:Pt:Siero:Ord:Line blot
Synonyms: Anticorpi IgM anticorpo Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) sulfatide As.IgM:aanwezigheid:moment:serum:ordinaal:lijnblot
Synonyms: antistof; antilichaam
zh-CN Chinese (China) 硫酸脑苷脂 抗体.IgM:存在情况或阈值:时间点:血清:序数型:线点印迹法
Synonyms: Ab.IgM;IgM;抗体 IgM Ab;自身抗体 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫球蛋白 M 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 时刻;随机;随意;瞬间 硫脂 Ab 硫脂 Ab.IgM 硫脂;硫脑苷脂;硫苷脂;脑硫脂 硫脂抗体 硫脂抗体.IgM 硫脑苷脂 Ab 硫脑苷脂 Ab.IgM 硫脑苷脂抗体 硫脑苷脂抗体.IgM 硫苷脂 Ab 硫苷脂 Ab.IgM 硫苷脂抗体 硫苷脂抗体.IgM 硫酸脑苷脂 Ab 硫酸脑苷脂 Ab.IgM 硫酸脑苷脂 IgM 线点杂交技术;线点杂交法;线条状印迹法 脑硫脂 Ab 脑硫脂 Ab.IgM 脑硫脂抗体 脑硫脂抗体.IgM 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目(非微生物学);血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验(非微生物学);血清学试验类 (非微生物学);血清类

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