82473-0

Borrelia mayonii oppA1 gene [Presence] in Blood by NAA with non-probe detection

Active

Term Description

The DNA amplification target is the 283-bp plasminogen-binding protein gene (oppA1), which is present at a frequency of one copy per organism in all four pathogenic species of the Borrelia burgdorferi sensu lato genogroup (Borrelia burgdorferi sensu stricto, Borrelia afzelii, Borrelia garinii, and Borrelia mayonii). Melting curve analysis is used to identify B. mayonii and differentiate it from the other three species.

Part Descriptions

LP220481-8 Borrelia mayonii oppA1 gene
Borrelia mayonii is the proposed name for a bacterial species found in 2013, causing Lyme disease in six people who live in the upper Midwestern United States. Worldwide, Lyme disease is caused by three main species of bacteria: Borrelia burgdorferi, B. afzelii, and B. garinii. Borrelia burgdorferi causes Lyme disease in the United States, while the other two species are the leading causes of Lyme disease in Europe and Asia. B. mayonii is a new species that is genetically distinct from these three species and is the only species besides B. burgdorferi shown to cause Lyme disease in North America. B. mayonii has been identified in blacklegged (or "deer") ticks collected in several counties in northwestern Wisconsin and Minnesota. It is highly likely, however, that infected ticks occur in other areas of both states. Limited information suggests that illness caused by B. mayonii is similar to that caused by B. burgdorferi, but with a few possible differences. Like B. burgdorferi, B. mayonii causes fever, headache, rash, and neck pain in the early stages of infection (days after exposure) and arthritis in later stages of infection (weeks after exposure). Unlike B. burgdorferi however, B. mayonii appears to be associated with nausea and vomiting, diffuse rashes, and a higher concentration of bacteria in the blood. Patients infected with B. mayonii have been successfully treated with a 2-4 week course of doxycycline. Amoxicillin, ceftriaxone, and cefuroxime have also been used. Source: Centers for Disease Control and Prevention, CDC: Borrelia mayonii

LP220481-8 Borrelia mayonii oppA1 gene
The oppA1 gene is a member of a family of three genes; oppA-1, oppA-2, and oppA-3, that encode predicted peptide-binding proteins. Peptide-binding protein dependent transport systems are recognized to play important roles in microbial cell signaling and virulence. PMID: 9712756 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Borrelia mayonii oppA1 gene:PrThr:Pt:Bld:Ord:Non-probe.amp.tar
Long Common Name: Borrelia mayonii oppA1 gene [Presence] in Blood by NAA with non-probe detection
Short Name: B mayonii oppA1 Bld Ql NAA+n-prb
Display Name: B. mayonii oppA1 gene NAA+non-probe Ql (Bld)
Consumer Name Alpha Get Info: Borrelia mayonii oppA1 gene, Blood

Part Model Get Info

Component
Borrelia mayonii oppA1 gene
LP220481-8
- Analyte
  Borrelia mayonii oppA1 gene
  LP220481-8
  - Component Numerator
    Borrelia mayonii oppA1 gene
    LP220481-8
    - Component Numerator Core
      Borrelia mayonii oppA1 gene
      LP220481-8
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Bld
LP7057-5
- System Core
  Bld
  LP7057-5
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Non-probe.amp.tar
LP208998-7

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.82 (MIN)
Change Reason: Release 2.68: COMPONENT: Removed parentheses from Component for consistency and accuracy.; Previous Releases:
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
90892-1	Borrelia sp panel - Blood by NAA with non-probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG41633-5	Borrelia

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Borrelia mayonii gen oppA1:Přítomnost nebo práh:Časový bod:Krev:Ordinální:Amplifikace nukleových kyselin s detekcí bez sondy
el-GR	Greek (Greece)	Γονίδιο Borrelia mayonii oppA1:PrThr:Pt:Αίμα:Ord:Χωρίς ανιχνευτή.ενίσχυση.στόχου Synonyms: MICRO Ord PrThr Pt Αίμα Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Γονίδιο Γονίδιο Borrelia mayonii oppA1 Χωρίς ανιχνευτή.ενίσχυση.στόχου
es-ES	Spanish (Spain)	Gen oppA1 de Borrelia mayonii:PrThr:Punto temporal:Sangre:Ord:Amplificación del objetivo no basado en sonda
es-MX	Spanish (Mexico)	Gen oppA1 de Borrelia mayonii:Presencia o umbral:Punto temporal:Sangre:Ordinal:Amplificación de ácidos nucleicos con detección sin sonda
fr-FR	French (France)	Borrelia mayonii gène oppA1:Présence/Seuil:Ponctuel:Sang:Qualitatif:Non-PCR amplification de cible
it-IT	Italian (Italy)	Borrelia mayonii (oppA1), gene:PrThr:Pt:Sangue:Ord:Non-sonda.amp.tar Synonyms: Amplificazione target non basata su sonda Gene Borrelia mayonii (oppA1) Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sangue Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
pl-PL	Polish (Poland)	Borrelia mayonii oppA1 gen:granica wykrywalności:punkt w czasie:krew:uporządkowany:bez sondy.amplifikacja.cel Synonyms: amplifikacja kwasu nukleinowego z detekcją bez użycia sondy amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy Gen oppA1 Borrelia mayonii
zh-CN	Chinese (China)	梅奥疏螺旋体 oppA1 基因:存在情况或阈值:时间点:全血:序数型:非探针法.基因扩增.靶向 Synonyms: 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向借助靶向扩增的非探针方法;借助靶向扩增的非探针法;非探针法.扩增.靶向存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间梅奥疏螺旋体（梅奥螺旋体、梅氏疏螺旋体、梅奥型包柔氏螺旋体） oppA1 基因经过扩增的脱氧核糖核酸探针血;血液遗传基因;遗传因子;吉恩;生物基因

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.