82475-5

Borrelia miyamotoi glpQ gene [Presence] in Blood by NAA with non-probe detection

Active

Term Description

The DNA amplification target is a gene encoding glycerophosphodiester phosphodiesterase (GlpQ), which is specific to the Borrelia species in the relapsing fever group. This gene is not found in the Borrelia species that cause Lyme disease. Melting curve analysis is then used to identify the organism as B. miyamotoi. A positive result is consistent with active or recent infection.

Part Description

LP221168-0 Borrelia miyamotoi glpQ gene
Borrelia miyamotoi is a spirochetal bacterium that is closely related to the Borrelia species that causes tick-borne relapsing fever (TBRF), and it is more distantly related to the Borrelia species that cause Lyme disease. First identified in 1995 in ticks from Japan, B. miyamotoi has since been detected in two species of North American ticks, the black-legged or "deer" tick (Ixodes scapularis) and the western black-legged tick (Ixodes pacificus). These ticks are already known to transmit several diseases, including Lyme disease, anaplasmosis, and babesiosis. Patients with B. miyamotoi infection are most likely to have fever, chills, and headache. Other common symptoms included body and joint pain and fatigue. Unlike Lyme disease, rash is uncommon, presenting in only 4 out of 51 patients. Patients infected with B. miyamotoi have been treated with a 2-4 week course of doxycycline, amoxicillin, or ceftriaxone. Fewer than 60 well-documented cases of human infection have been reported in the United States as of July 2015. The route of transmission of B. miyamotoi to humans has not been firmly established, but likely involves the bite of infected black-legged ticks. The glpQ gene encodes a periplasmic enzyme, glycerophosphodiester phosphodiesterase of 333 amino acids produced initially with a 25 residue long signal sequence. GlpQ is not found in Borrelia species that cause Lyme disease. Source: Regenstrief LOINC, CDC: B. miyamotoi

LOINC Names Get Info

Fully-Specified Name: Borrelia miyamotoi glpQ gene:PrThr:Pt:Bld:Ord:Non-probe.amp.tar
Long Common Name: Borrelia miyamotoi glpQ gene [Presence] in Blood by NAA with non-probe detection
Short Name: B miyamotoi glpQ Bld Ql NAA+n-prb
Display Name: B. miyamotoi glpQ gene NAA+non-probe Ql (Bld)
Consumer Name Alpha Get Info: Borrelia miyamotoi glpQ gene, Blood

Part Model Get Info

Component
Borrelia miyamotoi glpQ gene
LP221168-0
- Analyte
  Borrelia miyamotoi glpQ gene
  LP221168-0
  - Component Numerator
    Borrelia miyamotoi glpQ gene
    LP221168-0
    - Component Numerator Core
      Borrelia miyamotoi glpQ gene
      LP221168-0
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Bld
LP7057-5
- System Core
  Bld
  LP7057-5
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Non-probe.amp.tar
LP208998-7

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.82 (MIN)
Change Reason: Release 2.68: COMPONENT: Removed parentheses around the bacterial gene name based on current LONC naming model.; Previous Releases:
Order vs. Observation: Both
Common Test Rank Get Info: 17296

Member of these Panels

LOINC	Long Common Name
90892-1	Borrelia sp panel - Blood by NAA with non-probe detection
101647-6	Ehrlichiosis and Anaplasmosis and Babesiosis and Borrelia miyamotoi DNA panel - Serum, Plasma or Blood by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG41633-5	Borrelia

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Borrelia miyamotoi gen glpQ:Přítomnost nebo práh:Časový bod:Krev:Ordinální:Amplifikace nukleových kyselin s detekcí bez sondy
el-GR	Greek (Greece)	Γονίδιο Borrelia miyamotoi glpQ:PrThr:Pt:Αίμα:Ord:Χωρίς ανιχνευτή.ενίσχυση.στόχου Synonyms: MICRO Ord PrThr Pt Αίμα Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Βακτήριο Borrelia miyamotoi Γονίδιο Γονίδιο Borrelia miyamotoi glpQ Χωρίς ανιχνευτή.ενίσχυση.στόχου
es-ES	Spanish (Spain)	Gen glpQ de Borrelia miyatomoi:PrThr:Punto temporal:Sangre:Ord:Amplificación del objetivo no basado en sonda
es-MX	Spanish (Mexico)	Gen glpQ de Borrelia miyamotoi:Presencia o umbral:Punto temporal:Sangre:Ordinal:Amplificación de ácidos nucleicos con detección sin sonda
fr-FR	French (France)	Borrelia miyamotoi gène glpQ:Présence/Seuil:Ponctuel:Sang:Qualitatif:Non-PCR amplification de cible
it-IT	Italian (Italy)	Borrelia miyamotoi (glpQ), gene:PrThr:Pt:Sangue:Ord:Non-sonda.amp.tar Synonyms: Amplificazione target non basata su sonda Gene Borrelia miyamotoi (glpQ) Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sangue Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
pl-PL	Polish (Poland)	Borrelia miyamotoi glpQ gen:granica wykrywalności:punkt w czasie:krew:uporządkowany:bez sondy.amplifikacja.cel Synonyms: amplifikacja kwasu nukleinowego z detekcją bez użycia sondy amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy Gen glpQ Borrelia miyamotoi
zh-CN	Chinese (China)	宫本疏螺旋体 glpQ 基因:存在情况或阈值:时间点:全血:序数型:非探针法.基因扩增.靶向 Synonyms: 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向借助靶向扩增的非探针方法;借助靶向扩增的非探针法;非探针法.扩增.靶向存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间米亚莫托疏螺旋体 glpQ 基因;宫本伯氏包柔螺旋体 glpQ 基因米亚莫托疏螺旋体;宫本伯氏包柔螺旋体经过扩增的脱氧核糖核酸探针血;血液遗传基因;遗传因子;吉恩;生物基因

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.