Version 2.73

82476-3Borrelia miyamotoi glpQ gene [Presence] in Cerebral spinal fluid by NAA with non-probe detectionActive

Term Description

The DNA amplification target is a gene encoding glycerophosphodiester phosphodiesterase (GlpQ), which is specific to the Borrelia species in the relapsing fever group. This gene is not found in the Borrelia species that cause Lyme disease. Melting curve analysis is then used to identify the B. miyamotoi organism. A positive result is consistent with active or recent infection. B. miyamotoi infections of the central nervous system are associated with the symptoms and signs of meningoencephalitis.
Source: Regenstrief LOINC

Part Description

LP221168-0   Borrelia miyamotoi glpQ gene
Borrelia miyamotoi is a spirochetal bacterium that is closely related to the Borrelia species that causes tick-borne relapsing fever (TBRF), and it is more distantly related to the Borrelia species that cause Lyme disease. First identified in 1995 in ticks from Japan, B. miyamotoi has since been detected in two species of North American ticks, the black-legged or "deer" tick (Ixodes scapularis) and the western black-legged tick (Ixodes pacificus). These ticks are already known to transmit several diseases, including Lyme disease, anaplasmosis, and babesiosis. Patients with B. miyamotoi infection are most likely to have fever, chills, and headache. Other common symptoms included body and joint pain and fatigue. Unlike Lyme disease, rash is uncommon, presenting in only 4 out of 51 patients. Patients infected with B. miyamotoi have been treated with a 2-4 week course of doxycycline, amoxicillin, or ceftriaxone. Fewer than 60 well-documented cases of human infection have been reported in the United States as of July 2015. The route of transmission of B. miyamotoi to humans has not been firmly established, but likely involves the bite of infected black-legged ticks. The glpQ gene encodes a periplasmic enzyme, glycerophosphodiester phosphodiesterase of 333 amino acids produced initially with a 25 residue long signal sequence. GlpQ is not found in Borrelia species that cause Lyme disease. Source: Regenstrief LOINC, CDC: B. miyamotoi

Fully-Specified Name

Borrelia miyamotoi glpQ gene

Additional Names

Short Name
B miyamotoi glpQ CSF Ql NAA+non-probe
Display Name
B. miyamotoi glpQ gene NAA+non-probe Ql (CSF)
Consumer Name Alpha
Borrelia miyamotoi glpQ gene, Spinal fluid

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

First Released
Version 2.58
Last Updated
Version 2.68
Change Reason
Release 2.68: COMPONENT: Removed parentheses around the bacterial gene name based on current LONC naming model.; Previous Releases:
Order vs. Observation

Member of these Groups

LG41633-5 Borrelia

Language Variants Get Info

zh-CNChinese (China)
宫本疏螺旋体 glpQ 基因:存在情况或阈值:时间点:脑脊液:序数型:非探针法.基因扩增.靶向
fr-FRFrench (France)
Borrelia miyamotoi glpQ gène:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Non-PCR amplification de cible
it-ITItalian (Italy)
Borrelia miyamotoi (glpQ), gene:PrThr:Pt:LCS:Ord:Non-sonda.amp.tar
es-MXSpanish (Mexico)
Gen glpQ de Borrelia miyamotoi:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Amplificación de ácidos nucleicos con detección sin sonda
es-ESSpanish (Spain)
Gen glpQ de Borrelia miyatomoi:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Amplificación del objetivo no basado en sonda

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