Version 2.78

Term Description

The quantitative ratios of various steroids in urine are measured to diagnose conditions such as 17-alpha-, 21-, and 11-beta hydroxylase deficiencies, pseudohypoaldosteronismus, 3-beta hydroxysteroid dehydrogenase deficiency, corticosterone methyl oxidase deficiency, 11-beta hydroxysteroid dehydrogenase types 1 and 2 deficiency, and 5-alpha reductase deficiency. The results along with clinical symptoms and past medical history are used for the assessment and treatment of the associated deficiency or condition. Below are examples of various disorders and their associated urinary findings:
1. 17-alpha hydroxylase deficiency: (THA+THB+5aTHB)/(THE+THF+5aTHF) > 10, (THA+THB+5aTHB)/(AN+ET) > 10.
2. 21-hydroxylase deficiency: 17HP/(THE+THF+5aTHF) > 0.25, PT/(THE+THF+5aTHF) > 0.25.
3. 11-beta HSD2 deficiency: (THF+5aTHF)/THE > 3
4. 11-beta HSD1 deficiency: (THF+5aTHF)/THE < 0.1
5. 11-beta hydroxylase deficiency: 100*THS/(THE+THF+5aTHF) > 10, 100*THDOC/(THE+THF+5aTHF) > 10
6. Pseudohypoaldosteronismus: 100*THALDO/(THE+THF+5aTHF) > 5
7. 5-alpha reductase: ET/AN > 5, THF/5aTHF > 10
Where AN = Androsterone, ET= etiocholanolone, 17HP= metabolites of 17-OH-progesterone (pregnandiol, pregnantriol, 17-OH-pregnanolone), THA = tetrahydro compound A, THB = tetrahydrocorticosterone, 5aTHB =5 alpha tetrahydrocorticosterone, THE = tetrahydrocortisone, THF = Tetrahydrocortisone, 5aTHF = 5a-tetrahydrocortisone or Allo-tetrahydrocortisone, THS = tetrahydrodeoxycortisol, THALDO = tetrahydroaldosterone, and THDOC =tetrahydrodeoxycortisone
[NLM Catalog ID: 101631718]
Source: Regenstrief LOINC

Fully-Specified Name

Component
11-Dehydrocorticosterone+tetrahydrocorticosterone+Allo-tetrahydrocorticosterone/Androsterone+etiocholanolone
Property
SRto
Time
24H
System
Urine
Scale
Qn
Method

Additional Names

Short Name
11-DHC+THB+5a-THB/An+Et 24h Ur-sRto
Display Name
11-Dehydrocorticosterone+tetrahydrocorticosterone+allo-tetrahydrocorticosterone/Androsterone+etiocholanolone (24H U) [Molar ratio]
Consumer Name Alpha Get Info
11-Dehydrocorticosterone+tetrahydrocorticosterone+allo-tetrahydrocorticosterone/Androsterone+etiocholanolone, Urine

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.58
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
73885-6 Steroid fractions panel - 24 hour Urine

Member of these Groups Get Info

LOINC Group Group Name
LG37430-2 11-Dehydrocorticosterone+tetrahydrocorticosterone+Allo-tetrahydrocorticosterone/Androsterone+etiocholanolone|SRto|Urine

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) 11-Dehdrocorticosterona+tetrahidrocorticosterone+alo-tetrahidrocorticosterona/Androsterona+etiocolanolona:Relacion de Sustancia:24 horas:Orina:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) 11-deshidrocorticosterona + tetrahidrocorticosterona + alo-tetrahidrocorticosterona / androsterona + etiocolanolona:Proporción de sustancia:24H:Orina:Cuantitativo:
fr-FR French (France) 11-déhydrocorticostérone+tétrahydrocorticostérone+Allo-tétrahydrocorticostérone/androstérone+étiocholanolone:Moles ratio:24H:Urine:Numérique:
it-IT Italian (Italy) 11-Deidrocorticosterone+tetraidrocorticosterone+allo-tetraidrocorticosterone/Androsterone+etiocholanolone:Srto:24h:Urine:Qn:
Synonyms: 24 Ore Chimica Rapporto di sostanza
nl-NL Dutch (Netherlands) 11-dehydrocorticosteron + tetrahydrocorticosteron + allo-tetrahydrocorticosteron/androsteron + etiocholanolon:molaire verhouding:24 uur:urine:kwantitatief:
Synonyms: 24U
zh-CN Chinese (China) 11-脱氢皮质酮+四氢皮质酮+别-四氢皮质酮/雄酮+本胆烷醇酮:物质的量比率:24小时:尿液:定量型:
Synonyms: 11-脱氢皮质酮+四氢皮质酮（THB、四氢皮质甾酮）+别-四氢皮质酮（THB、四氢皮质甾酮） 1天;1日;24.0小时;一天;一日;二十四个小时;二十四小时 5 Beta-雄酮;5β-雄酮;Etiochol;初胆烷醇酮;还原尿睾酮 Androster;雄性酮 THB;四氢皮质甾酮 别-四氢皮质甾酮 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 尿;小便;下泉 物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值 雄酮（雄性酮）+本胆烷醇酮（5 Beta-雄酮、5β-雄酮、Etiochol、初胆烷醇酮、还原尿睾酮）

Example Units

Unit Source
{ratio} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=82846-7