82846-7

11-Dehydrocorticosterone+tetrahydrocorticosterone+allo-tetrahydrocorticosterone/Androsterone+etiocholanolone [Molar ratio] in 24 hour Urine

Active

Term Description

The quantitative ratios of various steroids in urine are measured to diagnose conditions such as 17-alpha-, 21-, and 11-beta hydroxylase deficiencies, pseudohypoaldosteronismus, 3-beta hydroxysteroid dehydrogenase deficiency, corticosterone methyl oxidase deficiency, 11-beta hydroxysteroid dehydrogenase types 1 and 2 deficiency, and 5-alpha reductase deficiency. The results along with clinical symptoms and past medical history are used for the assessment and treatment of the associated deficiency or condition. Below are examples of various disorders and their associated urinary findings:
1. 17-alpha hydroxylase deficiency: (THA+THB+5aTHB)/(THE+THF+5aTHF) > 10, (THA+THB+5aTHB)/(AN+ET) > 10.
2. 21-hydroxylase deficiency: 17HP/(THE+THF+5aTHF) > 0.25, PT/(THE+THF+5aTHF) > 0.25.
3. 11-beta HSD2 deficiency: (THF+5aTHF)/THE > 3
4. 11-beta HSD1 deficiency: (THF+5aTHF)/THE < 0.1
5. 11-beta hydroxylase deficiency: 100*THS/(THE+THF+5aTHF) > 10, 100*THDOC/(THE+THF+5aTHF) > 10
6. Pseudohypoaldosteronismus: 100*THALDO/(THE+THF+5aTHF) > 5
7. 5-alpha reductase: ET/AN > 5, THF/5aTHF > 10
Where AN = Androsterone, ET= etiocholanolone, 17HP= metabolites of 17-OH-progesterone (pregnandiol, pregnantriol, 17-OH-pregnanolone), THA = tetrahydro compound A, THB = tetrahydrocorticosterone, 5aTHB =5 alpha tetrahydrocorticosterone, THE = tetrahydrocortisone, THF = Tetrahydrocortisone, 5aTHF = 5a-tetrahydrocortisone or Allo-tetrahydrocortisone, THS = tetrahydrodeoxycortisol, THALDO = tetrahydroaldosterone, and THDOC =tetrahydrodeoxycortisone
[NLM Catalog ID: 101631718]
Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: 11-Dehydrocorticosterone+tetrahydrocorticosterone+Allo-tetrahydrocorticosterone/Androsterone+etiocholanolone:SRto:24H:Urine:Qn:
Long Common Name: 11-Dehydrocorticosterone+tetrahydrocorticosterone+allo-tetrahydrocorticosterone/Androsterone+etiocholanolone [Molar ratio] in 24 hour Urine
Short Name: 11-DHC+THB+5a-THB/An+Et 24h Ur-sRto
Display Name: 11-Dehydrocorticosterone+tetrahydrocorticosterone+allo-tetrahydrocorticosterone/Androsterone+etiocholanolone (24H U) [Molar ratio]
Consumer Name Alpha Get Info: 11-Dehydrocorticosterone+tetrahydrocorticosterone+allo-tetrahydrocorticosterone/Androsterone+etiocholanolone, Urine

Part Model Get Info

Component
11-Dehydrocorticosterone+tetrahydrocorticosterone+Allo-tetrahydrocorticosterone/Androsterone+etiocholanolone
LP284656-8
- Analyte
  11-Dehydrocorticosterone+tetrahydrocorticosterone+Allo-tetrahydrocorticosterone/Androsterone+etiocholanolone
  LP284656-8
  - Component Numerator
    11-Dehydrocorticosterone+tetrahydrocorticosterone+allo-tetrahydrocorticosterone
    LP230219-0
    - Component Numerator Core
      11-Dehydrocorticosterone+tetrahydrocorticosterone+allo-tetrahydrocorticosterone
      LP230219-0
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    Androsterone+etiocholanolone
    LP230209-1
    - Component Denominator Core
      Androsterone+etiocholanolone
      LP230209-1
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
SRto
LP6868-6
Time
24H
LP6924-7
- Time Core
  24H
  LP6924-7
- Time Modifier
  NULL
System
Urine
LP7681-2
- System Core
  Urine
  LP7681-2
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.58 (ADD)
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
73885-6	Steroid fractions panel - 24 hour Urine

Member of these Groups Get Info

LOINC Group	Group Name
LG37430-2	11-Dehydrocorticosterone+tetrahydrocorticosterone+Allo-tetrahydrocorticosterone/Androsterone+etiocholanolone\|SRto\|Urine

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	11-dehydrokortikosteron+tetrahydrokortikosteron+allo-tetrahydrokortikosteron/androsteron+etiocholanolon:Látkový poměr:24 hodin:Moč:Kvantitativní:
el-GR	Greek (Greece)	11-Δεϋδροκορτικοστερόνη+τετραϋδροκορτικοστερόνη+αλλο-τετραϋδροκορτικοστερόνη/Ανδροστερόνη+ετιοχολανολόνη:SRto:24H:Ούρα:Qn: Synonyms: 11-Δεϋδροκορτικοστερόνη+τετραϋδροκορτικοστερόνη+αλλο-τετραϋδροκορτικοστερόνη 24H CHEM Qn SRto Αλλοτετραϋδροκορτικοστερόνη Ανδροστερόνη Ανδροστερόνη+ετιοχολανολόνη Ετιοχολανολόνη Ούρα Τετραϋδροκορτικοστερόνη
es-ES	Spanish (Spain)	11-Dehdrocorticosterona+tetrahidrocorticosterone+alo-tetrahidrocorticosterona/Androsterona+etiocolanolona:Relacion de Sustancia:24 horas:Orina:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	11-deshidrocorticosterona + tetrahidrocorticosterona + alo-tetrahidrocorticosterona / androsterona + etiocolanolona:Proporción de sustancia:24H:Orina:Cuantitativo:
fr-FR	French (France)	11-déhydrocorticostérone+tétrahydrocorticostérone+Allo tétrahydrocorticostérone/androstérone+étiocholanolone:Moles ratio:24H:Urine:Numérique:
it-IT	Italian (Italy)	11-Deidrocorticosterone+tetraidrocorticosterone+allo-tetraidrocorticosterone/Androsterone+etiocholanolone:Srto:24h:Urine:Qn: Synonyms: 24 Ore Chimica Rapporto di sostanza
nl-NL	Dutch (Netherlands)	11-dehydrocorticosteron + tetrahydrocorticosteron + allo-tetrahydrocorticosteron/androsteron + etiocholanolon:molaire verhouding:24 uur:urine:kwantitatief: Synonyms: 24U
pl-PL	Polish (Poland)	11-Dehydrokortykosteron+ tetrahydrokortykosteron + allo-tetrahydrokortykosteron/androsteron+etiocholanolon:współczynnik molowy:24h:mocz:ilościowy: Synonyms: 24 godziny ADT
zh-CN	Chinese (China)	11-脱氢皮质酮+四氢皮质酮+别-四氢皮质酮/雄酮+本胆烷醇酮:物质的量比率:24小时:尿液:定量型: Synonyms: 11-脱氢皮质酮+四氢皮质酮（THB、四氢皮质甾酮）+别-四氢皮质酮（THB、四氢皮质甾酮） 1天;1日;24.0小时;一天;一日;二十四个小时;二十四小时 5 Beta-雄酮;5β-雄酮;Etiochol;初胆烷醇酮;还原尿睾酮 Androster;雄性酮 THB;四氢皮质甾酮别-四氢皮质甾酮化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺尿;小便;下泉物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值雄酮（雄性酮）+本胆烷醇酮（5 Beta-雄酮、5β-雄酮、Etiochol、初胆烷醇酮、还原尿睾酮）

Example Units

Unit	Source
{ratio}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.