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Term Description

The quantitative ratios of various steroids in urine are measured to diagnose conditions such as 17-alpha-, 21-, and 11-beta hydroxylase deficiencies, pseudohypoaldosteronismus, 3-beta hydroxysteroid dehydrogenase deficiency, corticosterone methyl oxidase deficiency, 11-beta hydroxysteroid dehydrogenase types 1 and 2 deficiency, and 5-alpha reductase deficiency. The results along with clinical symptoms and past medical history are used for the assessment and treatment of the associated deficiency or condition. Below are examples of various disorders and their associated urinary findings:
1. 17-alpha hydroxylase deficiency: (THA+THB+5aTHB)/(THE+THF+5aTHF) > 10, (THA+THB+5aTHB)/(AN+ET) > 10.
2. 21-hydroxylase deficiency: 17HP/(THE+THF+5aTHF) > 0.25, PT/(THE+THF+5aTHF) > 0.25.
3. 11-beta HSD2 deficiency: (THF+5aTHF)/THE > 3
4. 11-beta HSD1 deficiency: (THF+5aTHF)/THE < 0.1
5. 11-beta hydroxylase deficiency: 100*THS/(THE+THF+5aTHF) > 10, 100*THDOC/(THE+THF+5aTHF) > 10
6. Pseudohypoaldosteronismus: 100*THALDO/(THE+THF+5aTHF) > 5
7. 5-alpha reductase: ET/AN > 5, THF/5aTHF > 10
Where AN = Androsterone, ET= etiocholanolone, 17HP= metabolites of 17-OH-progesterone (pregnandiol, pregnantriol, 17-OH-pregnanolone), THA = tetrahydro compound A, THB = tetrahydrocorticosterone, 5aTHB =5 alpha tetrahydrocorticosterone, THE = tetrahydrocortisone, THF = Tetrahydrocortisone, 5aTHF = 5a-tetrahydrocortisone or Allo-tetrahydrocortisone, THS = tetrahydrodeoxycortisol, THALDO = tetrahydroaldosterone, and THDOC =tetrahydrodeoxycortisone
[NLM Catalog ID: 101631718]
Source: Regenstrief LOINC

Part Description

LP15816-9   Pregnanetriol
A metabolite of 17-ALPHA-HYDROXYPROTESTERONE, normally produced in small quantities by the GONADS and the ADRENAL GLANDS, found in URINE. An elevated urinary pregnanetriol is associated with CONGENITAL ADRENAL HYPERPLASIA with a deficiency of STEROID 21-HYDROXYLASE. Source: National Library of Medicine, MeSH 2006

LOINC Names Get Info

Fully-Specified Name
Pregnanetriol/Tetrahydrocortisone+tetrahydrocortisol+5-alpha tetrahydrocortisol:SRto:24H:Urine:Qn:
Long Common Name
Pregnanetriol/Tetrahydrocortisone+tetrahydrocortisol+5-alpha tetrahydrocortisol [Molar ratio] in 24 hour Urine
Short Name
Pregntrl/THE+THF+5a-THF 24h Ur-sRto
Display Name
Pregnanetriol/Tetrahydrocortisone+tetrahydrocortisol+5-alpha tetrahydrocortisol (24H U) [Molar ratio]
Consumer Name Alpha Get Info
Pregnanetriol/Tetrahydrocortisone+tetrahydrocortisol+5-alpha Tetrahydrocortisol, Urine

Part Model Get Info

  • Component
    Pregnanetriol/Tetrahydrocortisone+tetrahydrocortisol+5-alpha tetrahydrocortisol
    LP286892-7
    • Analyte
      Pregnanetriol/Tetrahydrocortisone+tetrahydrocortisol+5-alpha tetrahydrocortisol
      LP286892-7
      • Component Numerator
        Pregnanetriol
        LP15816-9
        • Component Numerator Core
          Pregnanetriol
          LP15816-9
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        Tetrahydrocortisone+tetrahydrocortisol+5-alpha tetrahydrocortisol
        LP230218-2
        • Component Denominator Core
          Tetrahydrocortisone+tetrahydrocortisol+5-alpha tetrahydrocortisol
          LP230218-2
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    SRto
    LP6868-6
  • Time
    24H
    LP6924-7
  • System
    Urine
    LP7681-2
    • System Core
      Urine
      LP7681-2
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.58 (ADD)
Order vs. Observation
Both

Member of these Panels

LOINCLong Common Name
73885-6Steroid fractions panel - 24 hour Urine

Member of these Groups Get Info

LOINC GroupGroup Name
LG37447-6Pregnanetriol/Tetrahydrocortisone+tetrahydrocortisol+5-alpha tetrahydrocortisol|SRto|Urine

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Pregnantriol/tetrahydrokortizon+tetrahydrokortizol+5-alfa-tetrahydrokortizol:Látkový poměr:24 hodin:Moč:Kvantitativní:
el-GRGreek (Greece)Πρεγνανετριόλη/Τετραϋδροκορτιζόνη+τετραϋδροκορτιζόλη+5-α τετραϋδροκορτιζόλη:SRto:24H:Ούρα:Qn:
Synonyms: 24H 5-α-τετραϋδροκορτιζόλη CHEM Qn SRto Ούρα Πρεγνανετριόλη Τετραϋδροκορτιζόλη Τετραϋδροκορτιζόνη Τετραϋδροκορτιζόνη+τετραϋδροκορτιζόλη+5-α τετραϋδροκορτιζόλη Τετραϋδροκοτιζόλη+αλλο-τετραϋδροκοτιζόλη
es-ESSpanish (Spain)Pregnantriol/Tetrahidrocortisona+tetrahidrocortisol+5-alfa-tetrahidrocortisol:Relacion de Sustancia:24 horas:Orina:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Pregnanetriol / tetrahidrocortisona + tetrahidrocortisol + 5-alfa tetrahidrocortisol:Proporción de sustancia:24H:Orina:Cuantitativo:
fr-FRFrench (France)Prégnanetriol/tétrahydrocortisone+tétrahydrocortisol+5-alpha tétrahydrocortisol:Moles ratio:24H:Urine:Numérique:
it-ITItalian (Italy)Pregnandiolo/Tetraidrocortisone+tetraidrocortisolo+5-alfa tetraidrocortisolo:Srto:24h:Urine:Qn:
Synonyms: 24 Ore Chimica Pregnanediolo Rapporto di sostanza
nl-NLDutch (Netherlands)pregnaantriol/tetrahydrocortison + tetrahydrocortisol + 5-alfa tetrahydrocortisol:molaire verhouding:24 uur:urine:kwantitatief:
Synonyms: 24U
zh-CNChinese (China)孕三醇/四氢可的松+四氢皮质醇+5-alpha 四氢皮质醇:物质的量比率:24小时:尿液:定量型:
Synonyms: 1天;1日;24.0小时;一天;一日;二十四个小时;二十四小时 5 Alpha-四氢皮质甾醇 5 Alpha-四氢皮醇 5-A 四氢皮质醇;5-α 四氢皮质醇;5-alpha（α、A） 四氢皮质醇（THC、THF、四氢皮质甾醇、四氢皮醇） 5α-四氢皮质甾醇 5α-四氢皮质醇 5α-四氢皮醇 THC;THF;四氢皮质甾醇;四氢皮醇 α 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 四氢可的松（四氢考的松）+四氢皮质醇（THC、THF、四氢皮质甾醇、四氢皮醇）+5-alpha（α、A） 四氢皮质醇（THC、THF、四氢皮质甾醇、四氢皮醇）;四氢可的松+四氢皮质醇+5-α四氢皮质醇 四氢皮质醇（THC、THF、四氢皮质甾醇、四氢皮醇）+别-四氢皮质醇（THC、THF、四氢皮质甾醇、四氢皮醇） 四氢考的松 尿;小便;下泉 物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值 阿尔法

Example Units

UnitSource
{ratio}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=82898-8