82924-2

PL-7 IgG Ab [Presence] in Serum by Immunoassay

Active

Part Description

LP30804-6 PL-7
Aminoacyl-tRNA synthetases (ARS) are enzymes that link amino acids to tRNA molecules and therefore play a key role in protein synthesis. Each ARS is specific for a single amino acid. [NCBI Books: NBK22356] Autoantibodies to ARS are a hallmark of connective tissue diseases including anti-synthetase syndrome (ASS) and idiopathic inflammatory myopathies such as polymyositis (PM) and dermatomyositis (DM). ASS, PM and DM have overlapping features, including myositis, arthralgia, skin manifestations and interstitial lung disease. Antibodies to several specific ARS enzymes have been identified, including anti-histidyl (anti-Jo-1), anti-threonyl (anti-PL-7), anti-alanyl (anti-PL-12), anti-glycyl (anti-Ej), anti-isoleucyl (anti-Oj), anti-asparaginyl (anti-Ks), anti-phenylalanyl (anti-Zo), and anti-tyrosyl (anti-Ha). Different antibodies or patterns of antibodies have been associated with specific clinical features. Anti-Jo-1, anti-Ej, and anti-PL-7 antibodies are associated with myositis, including classic DM, clinically amyopathic DM (CADM) and PM. Anti-PL-12 alone is associated with CADM or interstitial lung disease (ILD). Anti-Ej and anti-PL-12 together are associated with CADM. Anti-Ks and anti-Oj are associated with ILD alone. PMID: 23573256 Anti-Ha and anti-Zo antibodies are the most recent autoantibodies to be identified in patients with symptoms of ASS. PMID: 17392287 Identifying the particular anti-ARS antibodies associated with an individual patient's disease may help guide treatment and predict clinical outcomes. Source: Regenstrief LOINC, PMID: 23573256

LOINC Names Get Info

Fully-Specified Name: Pl-7 Ab.IgG:PrThr:Pt:Ser:Ord:IA
Long Common Name: PL-7 IgG Ab [Presence] in Serum by Immunoassay
Short Name: PL7 IgG Ser Ql IA
Display Name: PL-7 IgG IA Ql (S)
Consumer Name Alpha Get Info: PL-7 IgG antibody, Blood

Part Model Get Info

Component
PL-7 Ab.IgG
LP232474-9
- Analyte
  PL-7 Ab.IgG
  LP232474-9
  - Component Numerator
    PL-7 Ab.IgG
    LP232474-9
    - Component Numerator Core
      PL-7
      LP30804-6
    - Component Numerator Core Suffix
      Ab.IgG
      LP32401-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Ord
LP7751-3
Method
IA
LP217197-5

Example Answer List: LL2010-8

Source: Estonian Society of Laboratory Medicine

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6
Borderline			LA4259-3

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.58 (ADD)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	PL-7 IgG:Přítomnost nebo práh:Časový bod:Sérum:Ordinální:Imunoanalýza
el-GR	Greek (Greece)	PL-7 Αντισώματα IgG:PrThr:Pt:Ορός:Ord:IA Synonyms: IA Ord PL-7 PrThr Pt SERO Ανοσοσφαιρίνη G Αντίσωμα Αντισώματα IgG Ορός
es-ES	Spanish (Spain)	Pl-7 IgG:PrThr:Punto temporal:Suero:Ord:IA
es-MX	Spanish (Mexico)	PL-7 Ab.IgG:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunoensayo
et-EE	Estonian (Estonia)	PL-7 antikehad.IgG:PrThr:Pt:S:Ord:IA Synonyms: Immuunglobuliin G Järgarvuline Juhuslik Seerum
fr-CA	French (Canada)	Pl-7, IgG:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:IA
fr-FR	French (France)	PL-7 Ac IgG:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunoanalyse
fr-BE	French (Belgium)	Pl-7 Anticorps. IgG:PrThr:Temps ponctuel:Sérum:Ordinal:IA Synonyms: Anticorps
it-IT	Italian (Italy)	PL-7 Ab.IgG:PrThr:Pt:Siero:Ord:IA Synonyms: anticorpi IgG anticorpo Immunoassay Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL	Dutch (Netherlands)	PL-7 As.IgG:aanwezigheid:moment:serum:ordinaal:immunoassay Synonyms: antistof; antilichaam IA
pl-PL	Polish (Poland)	PL-7 Ab.IgG:granica wykrywalności:punkt w czasie:surowica:uporządkowany:metoda immunologiczna Synonyms: IgG przeciwciała IgG Przeciwciała IgG do PL-7 Treonylo-tRNA syntetaza
ru-RU	Russian (Russian Federation)	PL-7 Ат.IgG:PrThr:ТчкВрм:Сыв:Пор:IA Synonyms: Антитело Порядковый Сыворотка Точка во времени;Момент
tr-TR	Turkish (Turkey)	PL-7 Ab.IgG:MevcEşik:Zmlı:Ser:Srl:İA Synonyms: Ak Ak.IgG İmmünölçüm, immünoassay Mevcut
zh-CN	Chinese (China)	Pl-7 抗体.IgG:存在情况或阈值:时间点:血清:序数型:免疫测定法 Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 Pl-7 Ab 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型先天性炎性肌病先天性炎症性肌病免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间特发性炎性肌病血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

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Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.