82925-9

PM-SCL-100 IgG Ab [Presence] in Serum by Line blot

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Term Description

This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.

Part Description

LP102300-3 PM-SCL-100
Anti-PM-SCL antibodies (75kD and 100 kD) are anti-nuclear antibodies present in patients with polymyositis (PM), systemic sclerosis (SSc), and PM/SSc overlap syndromes. The PM-SCL antibodies are directed mainly against the 75kD antigen. Source: Regenstrief LOINC, PMID: 19220911

LOINC Names Get Info

Fully-Specified Name: PM-SCL-100 Ab.IgG:PrThr:Pt:Ser:Ord:Line blot
Long Common Name: PM-SCL-100 IgG Ab [Presence] in Serum by Line blot
Short Name: PM/SCL-100 IgG Ser Ql Line blot
Display Name: PM-SCL-100 IgG Line blot Ql (S)
Consumer Name Alpha Get Info: PM-SCL-100 IgG antibody, Blood

Part Model Get Info

Component
PM-SCL-100 Ab.IgG
LP102314-4
- Analyte
  PM-SCL-100 Ab.IgG
  LP102314-4
  - Component Numerator
    PM-SCL-100 Ab.IgG
    LP102314-4
    - Component Numerator Core
      PM-SCL-100
      LP102300-3
    - Component Numerator Core Suffix
      Ab.IgG
      LP32401-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Line blot
LP266806-1

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.66 (MIN)
Change Reason: This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	PM-SCL-100 IgG:Přítomnost nebo práh:Časový bod:Sérum:Ordinální:Line blot
de-AT	German (Austria)	Synonyms: PM-Scl-100-IgG-AK ql.
de-DE	German (Germany)	PM-SCL-100 Ak.IgG:Nachweis oder Schwellenwert:Zeitpunkt:Serum:Ordinal:Line-Blot
el-GR	Greek (Greece)	PM-SCL-100 Αντισώματα IgG:PrThr:Pt:Ορός:Ord:Γραμμή κηλίδωσης Synonyms: Ord PM-SCL-100 PrThr Pt SERO Ανοσοσφαιρίνη G Αντίσωμα Αντισώματα IgG Γραμμή κηλίδωσης Ορός
es-ES	Spanish (Spain)	PM-SCL-100 IgG:PrThr:Punto temporal:Suero:Ord:Line blot
es-MX	Spanish (Mexico)	PM-SCL-100 Ab.IgG:Presencia o umbral:Punto temporal:Suero:Ordinal:Mancha de línea
fr-FR	French (France)	PM-SCL-100 Ac IgG:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Blot en ligne
it-IT	Italian (Italy)	PM-SCL-100 Ab.IgG:PrThr:Pt:Siero:Ord:Line blot Synonyms: anticorpi IgG anticorpo Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL	Dutch (Netherlands)	PM-SCL-100 As.IgG:aanwezigheid:moment:serum:ordinaal:lijnblot Synonyms: antistof; antilichaam
zh-CN	Chinese (China)	PM-SCL-100 抗体.IgG:存在情况或阈值:时间点:血清:序数型:线点印迹法 Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 PM-SCL extractable nuclear 100kD;PM-Scl100;PM-SCL 可提取性核 100kD;Scleromyositis;硬化性肌炎;polymyositis;PM;多发性肌炎;systemic sclerosis;系统性硬化病;硬皮病;SSc;PM/Scl overlap syndrome;系统性硬化病与多发性肌炎重叠综合征;autoimmune disease;自身免疫性疾病依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间皮硬化症硬皮病硬皮病（Scleroderma，SCL）硬皮症线点杂交技术;线点杂交法;线条状印迹法血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.