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Term Description

This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.

Part Description

LP29153-1   Mitochondria M2
Mitochondrial Antibody is present in approximately 95% of patients with primary biliary cirrhosis (PBC). Mitochondrial M2 Antibody has an even higher specificity for PBC. Source: Quest Diagnostics Inc., Mitochondrial antibody

LOINC Names Get Info

Fully-Specified Name
Mitochondria M2 Ab.IgG:PrThr:Pt:Ser:Ord:Line blot
Long Common Name
Mitochondria M2 IgG Ab [Presence] in Serum by Line blot
Short Name
Mitochondria M2 IgG Ser Ql Line blot
Display Name
Mitochondria M2 IgG Line blot Ql (S)
Consumer Name Alpha Get Info
Mitochondria M2 IgG antibody, Blood

Part Model Get Info

  • Component
    Mitochondria M2 Ab.IgG
    LP39024-2
    • Analyte
      Mitochondria M2 Ab.IgG
      LP39024-2
      • Component Numerator
        Mitochondria M2 Ab.IgG
        LP39024-2
        • Component Numerator Core
          Mitochondria M2
          LP29153-1
        • Component Numerator Core Suffix
          Ab.IgG
          LP32401-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Line blot
    LP266806-1

Example Answer List: LL360-9

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)LA6577-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.66 (MIN)
Change Reason
This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.
Order vs. Observation
Both

Member of these Panels

LOINCLong Common Name
85092-5Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Mitochondrie M2 IgG:Přítomnost nebo práh:Časový bod:Sérum:Ordinální:Line blot
de-DEGerman (Germany)Mitochondrien M2 Ak.IgG:Nachweis oder Schwellenwert:Zeitpunkt:Serum:Ordinal:Line-Blot
el-GRGreek (Greece)Μιτοχόνδρια M2 Αντισώματα IgG:PrThr:Pt:Ορός:Ord:Γραμμή κηλίδωσης
Synonyms: Ord PrThr Pt SERO Ανοσοσφαιρίνη G Αντίσωμα Αντισώματα IgG Γραμμή κηλίδωσης Μιτοχόνδρια Μιτοχόνδρια M2 Ορός
es-ESSpanish (Spain)Mitocondrial (M2) IgG:PrThr:Punto temporal:Suero:Ord:Line blot
es-MXSpanish (Mexico)Mitocondrias M2 Ab.IgG:Presencia o umbral:Punto temporal:Suero:Ordinal:Mancha de línea
fr-CAFrench (Canada)Mitochondrie M2, IgG:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoessai sur bandelette
fr-FRFrench (France)Mitochondries M2 Ac IgG:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Blot en ligne
it-ITItalian (Italy)Mitocondri M2 Ab.IgG:PrThr:Pt:Siero:Ord:Line blot
Synonyms: anticorpi IgG anticorpo Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NLDutch (Netherlands)mitochondriaal M2 As.IgG:aanwezigheid:moment:serum:ordinaal:lijnblot
Synonyms: antistof; antilichaam
zh-CNChinese (China)线粒体 M2 抗体.IgG:存在情况或阈值:时间点:血清:序数型:线点印迹法
Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 AMA-M2 AMA-M2.IgG 丙酮酸脱氢酶 Ab 丙酮酸脱氢酶抗体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 线点杂交技术;线点杂交法;线条状印迹法 线粒体 M2 Ab 线粒体 M2 Ab.IgG 线粒体 M2 IgG 线粒体 M2 抗体（Mitochondria M2 Ab，AMA-M2） 线粒体特异性;线粒体的 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=82928-3