Version 2.74

Term Description

This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.
Source: Regenstrief LOINC

Part Description

LP69895-8   Sjogrens syndrome-A extractable nuclear 52kD
Antibodies against the 52-kd Ro(SS-A) protein are significantly associated with the primary Sjogren's syndrome (pSS). Source: Regenstrief LOINC

Fully-Specified Name

Component
Sjogrens syndrome-A extractable nuclear 52kD Ab.IgG
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
Line blot

Additional Names

Short Name
ENA SS-A 52kD IgG Ser Ql Line blot
Display Name
Sjogrens syndrome-A extractable nuclear 52kD IgG Line blot Ql (S)
Consumer Name Alpha Get Info
Sjogrens syndrome-A extractable nuclear 52kD IgG antibody, Blood

Example Answer List: LL2010-8

Source: Estonian Society of Laboratory Medicine
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6
Borderline LA4259-3

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.66
Change Reason
This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
85092-5 Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Ag extraible nuclear de 52 kD del Síndrome de Sjogrens IgG:PrThr:Punto temporal:Suero:Ord:Line blot
es-MX Spanish (Mexico) Síndrome de Sjogrens-A nuclear extraíble 52kD Ab.IgG:Presencia o umbral:Punto temporal:Suero:Ordinal:Mancha de línea
fr-CA French (Canada) Syndrome de Sjögren-a nucléaire soluble 52kD , IgG:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoessai sur bandelette
fr-FR French (France) SSA/Ro52 kD anticorps IgG:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Blot en ligne
it-IT Italian (Italy) Sjogren, sindrome -nucleare estraibile A 52kD Ab.IgG:PrThr:Pt:Siero:Ord:Line blot
Synonyms: anticorpi IgG anticorpo ENA Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant Sindrome di Sjorgen - nucleare estraibile A Sindrome di Sjorgen - nucleare estraibile A 52kD
nl-NL Dutch (Netherlands) syndroom van Sjögren-A extraheerbare nucleaire 52kD As.IgG:aanwezigheid:moment:serum:ordinaal:lijnblot
Synonyms: antistof; antilichaam
zh-CN Chinese (China) Sjogrens 综合征-a 可提取性核 52kD 抗体.IgG:存在情况或阈值:时间点:血清:序数型:线点印迹法
Synonyms: A 型 Ab.IgG;IgG;抗体 IgG Ab;自身抗体 ENA SS-A;Ro;Ro AB;Ro 抗体;Ro 抗原;Sjogren;Sjogrens 综合征-a ENA;Sjogrens 综合征-a 可提取性核 Ag;Sjogrens 综合征-a 可提取性核抗原;SSA;SS-A;干燥综合征-a 抗原 ENA;可提取性核 Ag;可提取性核抗原;可提取性核抗原(Extractable Nuclear Antigen,ENA);可提取性细胞核;可提取性细胞核 Ag;可提取性细胞核抗原;盐水可提取性核 Ag;盐水可提取性核抗原;盐水可提取性细胞核 Ag;盐水可提取性细胞核抗原 Sjogren 氏综合征 Sjogren 综合征 Sjogren's 综合征 SS 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 干燥综合征 干燥综合征(Sjogrens syndrome,SS) 时刻;随机;随意;瞬间 核;胞核 核心抗体IgG 核心抗原抗体.IgG 核心抗原抗体IgG 核抗体.IgG 核抗体IgG 核抗原抗体.IgG 核抗原抗体IgG 线点杂交技术;线点杂交法;线条状印迹法 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目(非微生物学);血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验(非微生物学);血清学试验类 (非微生物学);血清类

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=82933-3