83082-8

Cancer Ag 125 [Units/volume] in Serum or Plasma by Immunoassay

Active

Term Description

This term was created for, but is not limited in use to, bioMerieux's VIDAS CA 125 II assay, which is intended for the quantitative measurement of the OC
125 antigenic determinants in human serum or plasma.
Source: Regenstrief LOINC

Part Description

LP14543-0 Cancer Ag 125
CA 125 is an antigenic determinant associated with a mucin-like glycoprotein, molecular weight exceeding 500,000 Daltons. This determinant is recognized by the murine monoclonal antibody OC 125, which reacts with over 80% of epithelial ovarian cancers. Elevated CA 125 levels have been reported in subjects with serous, endometrioid, clear cell, and undifferentiated ovarian carcinoma adenocarcinoma of the endometrium or fallopian tube, as well as some nongynocologic malignancies and certain nonmalignant conditions. Elevated levels also have been observed in pregnant women, most often during the first trimester. CA 125 levels may have significant value in monitoring ovarian carcinoma patients. A persistently rising CA 125 value may be associated with progressive malignant disease and poor therapeutic response. A declining CA 125 value is indicative of favorable prognosis and good response to treatment. CA 125 levels may help predict whether an invasive second-look procedure such as laparoscopy or laparotomy is required after treatment for epithelial ovarian cancer.
I.A. KOELMA, M. NAP, C.J. RODENBURG, G.J. FLEUREN (1987) The value of tumour marker CA 125 in surgical pathology
Histopathology 11 (3) , 287-294 doi:10.1111/j.1365-2559.1987.tb02633. Source: Regenstrief Institute

Fully-Specified Name

Component: Cancer Ag 125
Property: ACnc
Time: Pt
System: Ser/Plas
Scale: Qn
Method: IA

Additional Names

Long Common Name: Cancer Ag 125 [Units/volume] in Serum or Plasma by Immunoassay
Short Name: Cancer Ag125 SerPl IA-aCnc
Display Name: Cancer Ag 125 IA Qn
Consumer Name Alpha Get Info: Cancer Ag 125, Blood

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.73
Order vs. Observation: Both
Common Test Rank Get Info: 18720

Member of these Panels

LOINC	Long Common Name
104551-7	Ovarian malignancy (ROMA) panel - Serum or Plasma

Member of these Groups Get Info

LOINC Group	Group Name
LG108-7	Cancer Ag 125\|ACnc\|Pt\|ANYBldSerPl

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	Cancer Antigen 125:Arbiträre Konzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:Immunoassay Synonyms: CA 125
el-GR	Greek (Greece)	Καρκινικό αντιγόνο 125:Αυθαίρετη συγκέντρωση:Χρονική στιγμή:Ορός/Πλάσμα:Ποσοτική:IA Synonyms: CA 125
es-ES	Spanish (Spain)	Ag de cáncer 125:Concentración arbitraria:Punto temporal:Suero o Plasma:Qn:IA Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Cáncer Ag 125:Concentración arbitraria:Punto temporal:Suero o Plasma:Cuantitativo:Inmunoensayo
et-EE	Estonian (Estonia)	Kasvajaantigeen CA 125:Acnc:Pt:S/P:Qn:IA Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA	French (Canada)	Ag carbohydraté 125:Concentration arbitraire:Temps ponctuel:Sérum/Plasma:Quantitatif:IA
fr-FR	French (France)	Carbohydrate antigène 125:Arbitraire/Volume:Ponctuel:Sérum/Plasma:Numérique:Immunoanalyse
fr-BE	French (Belgium)	Ag carbohydraté 125:Concentration arbitraire:Temps ponctuel:Sérum/Plasma:Quantitatif:IA Synonyms: Ca 125
it-IT	Italian (Italy)	Cancro, Ag 125:ACnc:Pt:Siero/Plasma:Qn:IA Synonyms: Antigene 125 di cancro Chimica Concentrazione Arbitraria Immunoassay Plasma Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL	Dutch (Netherlands)	CA125:eenheid/volume:moment:serum of plasma:kwantitatief:immunoassay Synonyms: IA kanker Ag 125
pl-PL	Polish (Poland)	CA 125 Ag:stężenie w jednostkach umownych:punkt w czasie:surowica lub osocze:ilościowy:metoda immunologiczna Synonyms: Antygen CA 125
ru-RU	Russian (Russian Federation)	Раковый Аг 125:ПроизвКонц:ТчкВрм:Сыв/Плаз:Колич:IA Synonyms: Количественный Плазма Произвольная концентрация Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	Kanser Ag 125:SçKons:Zmlı:Ser/Plaz:Kant:İA Synonyms: İmmünölçüm, immünoassay
zh-CN	Chinese (China)	癌抗原 125:任意型浓度:时间点:血清/血浆:定量型:免疫测定法 Synonyms: CA CA 125;OC125;癌 Ag 125;癌抗原 125（Cancer Antigen 125，CA 125）任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间癌癌 Ag 癌症抗原血清或血浆

Example Units

Unit	Source
[arb'U]/mL	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=83082-8

LOINC Copyright

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.