Version 2.79

Term Description

This term was created for, but is not limited in use to, bioMerieux's VIDAS CA 15-3 assay, which is intended for the quantitative measurement of the CA 15-3 levels in human serum or plasma.

Part Descriptions

LP15461-4   Cancer Ag 15-3
CA 15-3 is a tumor marker for breast cancer. It is derived from MUC1. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , CA 15-3

LP15461-4   Cancer Ag 15-3
Cancer antigen 15-3 (CA 15-3) is a mucin molecule and blood tumor marker used to gauge the response to treatment of invasive breast cancer. CA 15-3 is encoded by the MUC1 gene and is a transmembrane glycoprotein. CA 15-3 may contribute to the growth of breast tumors by preventing tumor cell cytolysis by cytotoxic T-cells or lymphokine-activated cells. It may also block the proliferation of T-cells by causing apoptosis. In addition, CA 15-3 has been found to be expressed over the entire cell in malignant breast tissue while normal breast tissue expresses CA 15-3 only on the apical side of the glanudular epithelial cells. The presence of CA 15-3 is not unique to patients with breast cancer, but can also be found in patients with lung, colorectal, ovarian, and pancreatic cancers. Patients with primary tumors tend to have lower levels of CA 15-3, though the average concentration and percentage of patients goes up as the tumor stage or size of the tumor increases. While only a small number of recurrences of local or regional tumors result in an increased CA 15-3 level, over 70% of patients with remote metastasis have much higher CA 15-3 levels. PMID: 10505206 Source: Regenstrief LOINC

Fully-Specified Name

Component
Cancer Ag 15-3
Property
ACnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method
IA

Additional Names

Long Common Name
Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
Short Name
Cancer Ag15-3 SerPl IA-aCnc
Display Name
Cancer Ag 15-3 IA Qn
Consumer Name Alpha Get Info
Cancer Ag 15-3, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.68 (MIN)
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG26852-0 Cancer Ag 15-3|ACnc|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Cancer Antigen 15-3:Arbiträre Konzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:Immunoassay
Synonyms: CA 15-3
el-GR Greek (Greece) Καρκινικό αντιγόνο 15-3:ACnc:Pt:Ορός/Πλάσμα:Qn:IA
Synonyms: ACnc Καρκινικό αντιγόνο 15-3 Καρκίνος
es-ES Spanish (Spain) Antígeno CA 15-3:Concentración arbitraria:Punto temporal:Suero o Plasma:Qn:IA
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Cáncer Ag 15-3:Concentración arbitraria:Punto temporal:Suero o Plasma:Cuantitativo:Inmunoensayo
et-EE Estonian (Estonia) Kasvajaantigeen CA 15-3:Acnc:Pt:S/P:Qn:IA
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA French (Canada) Ag carbohydraté 15-3:Concentration arbitraire:Temps ponctuel:Sérum/Plasma:Quantitatif:IA
fr-FR French (France) Carbohydrate antigène 15.3:Arbitraire/Volume:Ponctuel:Sérum/Plasma:Numérique:Immunoanalyse
fr-BE French (Belgium) Ag carbohydraté 15-3:Concentration arbitraire:Temps ponctuel:Sérum/Plasma:Quantitatif:IA
Synonyms: Ca 15.3
it-IT Italian (Italy) Cancro, Ag 15-3:ACnc:Pt:Siero/Plasma:Qn:IA
Synonyms: Antigene 15-3 di cancro Chimica Concentrazione Arbitraria Immunoassay Plasma Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL Dutch (Netherlands) CA15.3:eenheid/volume:moment:serum of plasma:kwantitatief:immunoassay
Synonyms: IA kanker Ag 15-3
pl-PL Polish (Poland) CA 15-3 Ag:stężenie w jednostkach umownych:punkt w czasie:surowica lub osocze:ilościowy:metoda immunologiczna
Synonyms: Antygen CA 15-3
ru-RU Russian (Russian Federation) Раковый Аг 15-3:ПроизвКонц:ТчкВрм:Сыв/Плаз:Колич:IA
Synonyms: Количественный Плазма Произвольная концентрация Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Kanser Ag 15-3:SçKons:Zmlı:Ser/Plaz:Kant:İA
Synonyms: İmmünölçüm, immünoassay
zh-CN Chinese (China) 癌抗原 15-3:任意型浓度:时间点:血清/血浆:定量型:免疫测定法
Synonyms: Ⅲ CA CA 153;CA 15-3;MUC-1 基因相关抗原 CA 15-3;癌 Ag 15-3 III 三 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 叁 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 癌 癌 Ag 癌症抗原 血清或血浆

Example Units

Unit Source
[arb'U]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=83083-6