Version 2.80

Term Description

This term was created for, but is not limited in use to, bioMerieux's VIDAS Anti-Tg assay, which is intended for the quantitative detection of thyroglobulin IgG autoantibodies in human serum or plasma.

Part Descriptions

LP14697-4   Thyroglobulin
Thyroglobulin (Tg) is a protein produced by and used entirely within the thyroid gland. Thyroglobulin is used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is stored in the thyroid in follicle cysts surrounded by colloid cells. Via a reaction with the enzyme thyroperoxidase, iodine is covalently bound to tyrosine residues in thyroglobulin molecules, forming monoiodotyrosine (MIT) and diiodotyrosine (DIT). Thyroxine is produced by linking two moieties of DIT. Combining one particle of MIT and one particle of DIT produces triiodothyronine. Proteases in lysosomes digest iodinated thyroglobulin, releasing T3 and T4. Thyroglobulin levels in the blood can be used as a tumor marker for certain kinds of thyroid cancer. Thyroglobulin levels in the blood can also be elevated in cases of Graves Disease. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Thyroglobulin (Wikipedia)

LP14697-4   Thyroglobulin
Thyroglobulin (Tg) is a glycoprotein homodimer produced by the thyroid gland. It is important in the synthesis of thyroxine and triiodothyronine, and is where the inactive forms of thyroid hormone and iodine are stored. Mutations in the Tg gene cause thyroid dyshormonogenesis resulting in goiter, and can be associated with moderate to severe congenital hypothyroidism. Polymorphisms in the Tg gene are associated with susceptibility to autoimmune thyroid diseases such as Graves disease or Hashimoto thyroiditis. [NCBI Gene ID:7038] Tg is an established tumor marker used in the diagnosis of differentiated thyroid carcinoma. PMID: 9543128 Source: Regenstrief LOINC

Reference Information

Type Source Reference
Webcontent Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. Thyroid Antibodies

Fully-Specified Name

Component
Thyroglobulin Ab.IgG
Property
ACnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method
IA

Additional Names

Long Common Name
Thyroglobulin IgG Ab [Units/volume] in Serum or Plasma by Immunoassay
Short Name
Thyroglob IgG SerPl IA-aCnc
Display Name
Thyroglobulin IgG IA Qn
Consumer Name Alpha Get Info
Thyroglobulin IgG antibody, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.58 (ADD)
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG22999-3 Thyroglobulin Ab.IgG|ACnc|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Θυρεοσφαιρίνη Αντισώματα IgG:ACnc:Pt:Ορός/Πλάσμα:Qn:IA
Synonyms: ACnc Ανοσοσφαιρίνη G Θυρεοσφαιρίνη
es-ES Spanish (Spain) Tiroglobulina IgG:Concentración arbitraria:Punto temporal:Suero o Plasma:Qn:IA
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Tiroglobulina Ab.IgG:Concentración arbitraria:Punto temporal:Suero o Plasma:Cuantitativo:Inmunoensayo
et-EE Estonian (Estonia) Türeoglobuliin antikehad.IgG:Acnc:Pt:S/P:Qn:IA
Synonyms: Immuunglobuliin G Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA French (Canada) Thyroglobuline, IgG:Concentration arbitraire:Temps ponctuel:Sérum/Plasma:Quantitatif:IA
fr-FR French (France) Thyroglobuline anticorps IgG:Arbitraire/Volume:Ponctuel:Sérum/Plasma:Numérique:Immunoanalyse
fr-BE French (Belgium) Thyroglobuline Anticorps. IgG:Concentration arbitraire:Temps ponctuel:Sérum/Plasma:Quantitatif:IA
Synonyms: Anticorps hTG
it-IT Italian (Italy) Tireoglobulina Ab.IgG:ACnc:Pt:Siero/Plasma:Qn:IA
Synonyms: anticorpi IgG anticorpo Chimica Concentrazione Arbitraria Immunoassay Plasma Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL Dutch (Netherlands) thyreoglobuline As.IgG:eenheid/volume:moment:serum of plasma:kwantitatief:immunoassay
Synonyms: antistof; antilichaam IA
ru-RU Russian (Russian Federation) Тиреоглобулин Ат.IgG:ПроизвКонц:ТчкВрм:Сыв/Плаз:Колич:IA
Synonyms: Антитело Количественный Плазма Произвольная концентрация Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Tiroglobulin Ab.IgG:SçKons:Zmlı:Ser/Plaz:Kant:İA
Synonyms: İmmünölçüm, immünoassay
zh-CN Chinese (China) 甲状腺球蛋白 抗体.IgG:任意型浓度:时间点:血清/血浆:定量型:免疫测定法
Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 TG;甲状球蛋白;甲状腺球朊;甲状腺球蛋白（Thyroglobulin，TG，Tg）;甲状腺球蛋白特异性 TgAbs 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 免疫球蛋白 G 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 抗甲状腺球蛋白 时刻;随机;随意;瞬间 甲状腺球蛋白 Ab 血清或血浆

Example Units

Unit Source
[IU]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=83117-2