Version 2.78

Term Description

The response of the tumor to neoadjuvant treatment, such as chemotherapy and radiotherapy. Chemotherapy and/or radiotherapy before resection is associated with significant downstaging and improved prognosis. These specimens require close gross examination and additional blocking to demonstrate tumor. The degree of tumor regression has been shown to correlate with prognosis. This term was created for, but not limited in use to, the Colorectal Cancer Structured Reporting Protocol (2nd Edition, 2012) developed by the Royal College of Pathologists of Australasia (RCPA).
Source: Regenstrief LOINC

Fully-Specified Name

Component
Response to neoadjuvant therapy
Property
PrThr
Time
Pt
System
Colorectal cancer specimen
Scale
Ord
Method

Additional Names

Short Name
Tumor resp to neoadjvt therapy
Display Name
Response to neoadjuvant therapy Ql (Colorectal cancer specimen)
Consumer Name Alpha Get Info
Response to neoadjuvant therapy, Colorectal cancer specimen

Example Answer List: LL4077-5

Source: The Royal College of Pathologists of Australasia
Answer Code Score Answer ID
No prior treatment LA26537-3
Complete response (Grade 0 - No viable cancer cells) LA26538-1
Moderate response (Grade 1 - Single cells or small groups of cancer cells) LA26539-9
Mminimal response (Grade 2 - Residual cancer outgrown by fibrosis) LA26540-7
Poor response (Grade 3 - Minimal or no tumor kill; extensive) LA26541-5

Basic Attributes

Class
PATH
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.71
Change Reason
This term is still in Trial status and upon further review, the System was updated from 'Specimen' to reflect that this concept is specific to the colorectal cancer reporting protocol.
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
85905-8 Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Respuesta a la terapia neoadyuvante:PrThr:Punto temporal:Cáncer colorectal:Ord:
es-MX Spanish (Mexico) Respuesta a la terapia neoadyuvante:Presencia o umbral:Punto temporal:Muestra de cáncer colorrectal:Ordinal:
it-IT Italian (Italy) Risposta a terapia neoadiuvante:PrThr:Pt:Campione di carcinoma del colon-retto:Ord:
Synonyms: Campione di tumore Neoplasia maligna Patologia Presenza o Soglia Punto nel tempo (episodio)
zh-CN Chinese (China) 对新辅助疗法的反应:存在情况或阈值:时间点:结直肠癌标本:序数型:
Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 受检物 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 对新辅助疗法（新辅助治疗）的反应（响应、应答）;新辅助疗法（新辅助治疗）的效果 时刻;随机;随意;瞬间 样品 样本 癌 癌（癌症、癌变）标本（样本、样品、试样） 结直肠癌（结肠直肠癌、大肠癌、大肠直肠癌）标本（样本、样品、试样）;结肠直肠癌标本;大肠癌标本;大肠直肠癌标本 试样

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=84891-1