Version 2.71

84922-4Cells.chromosome 7 monosomy/Cells counted in Blood or Tissue by FISHActive

Term Description

The percent of cells in blood or tissue containing a single copy of chromosome 7 (monosomy 7) can be detected by FISH based on the number of chromosome 7 probe signals and used for the diagnosis of acute myeloid leukemia or myelodysplastic syndrome. This term is used to report the number of cells that have a chromosome 7 deletion out of total number of cells examined (e.g. 80 out of 100 cells, or 80%). Results are also typically reported in ISCN (International System for Human Cytogenetic Nomenclature) format [LOINC: 62356-1]. This term is based, but not limited in use to, the Vysis LSI D7S486(7q31)/CEP 7(7p11.1-q11.1) probe kit. To report percentage results for the 7q31 (D7S486) probe deletion, used [LOINC: 84921-6].
Source: Regenstrief LOINC

Part Description

LP62864-1   FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, FISH

Fully-Specified Name

Cells.chromosome 7 monosomy/Cells counted

Additional Names

Short Name
Cells.Chr Mono 7/Cells NFr Bld/T FISH
Display Name
Cells.chromosome 7 monosomy/Cells counted FISH (Bld/Tiss)
Consumer Name Alpha
Cells.chromosome 7 monosomy/Cells Counted, Blood or tissue specimen

Basic Attributes

First Released
Version 2.58
Last Updated
Version 2.61
Order vs. Observation

Language Variants Get Info

zh-CNChinese (China)
细胞.染色体 7 单体性/已计数的细胞:计数型分数:时间点:全血/组织:定量型:FISH
nl-NLDutch (Netherlands)
cellen.chromosoom 7 monosomie/getelde cellen:getalsfractie:moment:bloed of weefsel:kwantitatief:FISH
fr-FRFrench (France)
Cellules chromosome 7 monosomie/cellules comptées:Fraction de nombres:Ponctuel:Sang/Tissu:Numérique:FISH
it-ITItalian (Italy)
Cellule.monosomia cromosoma 7/Cellule contate:NFr:Pt:Sangue/Tess:Qn:FISH
es-ESSpanish (Spain)
Monosomía del cromosoma 7/Contaje celular:Fracción numérica:Punto temporal:Sangre o tejido:Qn:Hibridación in situ fluoresente (FISH)

Example Units

Unit Source
% Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info