Version 2.80

Term Description

Antineuronal antibodies against NMDAR1 are detected and characterized based on immunofluorescence staining pattern on multiple neuronal, non-neuronal tissues, and transformed substrate cells.

Part Description

LP229977-6   N-methyl-D-aspartate receptor subunit 1
N-methyl-D-aspartate receptor 1 (NMDAR1) is subunit of NMDA receptors and belongs to the glutamate receptor channel superfamily. It is encoded by the GRIN1 (Glutamate [NMDA] receptor subunit zeta-1) gene located on chromosome 9q34.3.[UniProt: Q05586] Glutamate receptors are highly permeable to calcium and important for nervous system functioning. NMDAR1 antibodies are detected in patients with paraneoplastic syndromes, autoimmune encephalopathies and related conditions. Identification of specific antineuronal autoantibodies may direct evaluation for underlying malignancy. Characterization of autoantibody specificity may allow syndromic classification and assist in diagnosis and management. Source: Regenstrief LOINC

Fully-Specified Name

Component
N-methyl-D-aspartate receptor subunit 1 Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IF

Additional Names

Long Common Name
NMDAR subunit 1 Ab [Presence] in Serum by Immunofluorescence
Short Name
NMDAR1 Ab Ser Ql IF
Display Name
NMDAR subunit 1 Ab IF Ql (S)
Consumer Name Alpha Get Info
NMDAR subunit 1 antibody, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Both
Common Test Rank Get Info
14424

Member of these Groups Get Info

LOINC Group Group Name
LG50948-5 N-methyl-D-aspartate receptor subunit 1 Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Υπομονάδα 1 υποδοχέα N-μεθυλο-D-ασπαρτικού Αντίσωμα:PrThr:Pt:Ορός:Ord:Ανοσοφθορισμός
Synonyms: D N PrThr Ασπαρτικό Υποδοχέας N-μεθυλο-D-ασπαρτικού Υπομονάδα 1 υποδοχέα N-μεθυλο-D-ασπαρτικού
es-ES Spanish (Spain) Subunidad 1 del receptor de N-metil-D-aspartato (NMDAR-1) Anticuerpos:PrThr:Punto temporal:Suero:Ord:Inmunofluorescencia (IF)
es-MX Spanish (Mexico) Subunidad del receptor de N-metil-D-aspartato 1 Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunofluorescencia (IF)
fr-FR French (France) NMDAR1 anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunofluorescence
it-IT Italian (Italy) N-metil-D-aspartato, subunità 1 recettore Ab:PrThr:Pt:Siero:Ord:IF
Synonyms: anticorpo Immunofluorescenza (IF) Presenza o Soglia Punto nel tempo (episodio) Recettore dell''N-metil-D-aspartato; NMDAR Siero Sierologia (anticorpi e la maggior parte degli ant Subunità 1 del recettore dell''N-metil-D-aspartato
nl-NL Dutch (Netherlands) N-methyl-D-aspartaatreceptor subeenheid 1 As:aanwezigheid:moment:serum:ordinaal:immunofluorescentie
Synonyms: antistof; antilichaam IF
zh-CN Chinese (China) N-甲基-D-天冬氨酸受体亚单位 1 抗体:存在情况或阈值:时间点:血清:序数型:免疫荧光法
Synonyms: Ⅰ Ab;自身抗体 Asp;天冬氨酸;门冬氨酸 I IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 N 型 N-甲基-D-天冬氨酸受体亚基 1;N-甲基-D-天门冬氨酸受体亚单位 1;N-甲基-D-天门冬氨酸受体亚基 1;NMDAR 亚单位 1;NMDAR 亚基 1 N-甲基-D-天门冬氨酸（Asp、天冬氨酸、门冬氨酸）受体 Rh;Rhesus;恒河猴;猕猴;罗猴 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=84928-1