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Term Description

Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 2 (AMPAR2) antibodies are detected and characterized based on immunofluorescence staining pattern on multiple neuronal, non-neuronal tissues, and transformed substrate cells.

Part Description

LP229975-0   Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 2
Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptor 1 (AMPAR1) and AMPA receptor 2 (AMPAR2) antibodies target the AMPA receptor, an ionotropic glutamate receptor and key excitatory neurotransmitter. AMPA receptors are comprised of different combinations of four glutamate receptor subunits called GluA1-GluA4 (also known as GluR1-GluR4 and GluR-A to GluR-D). They are vital for brain development and function, such as memory and cognitive development. Detection of antineuronal autoantibodies against AMPA receptors aids in the diagnosis of autoimmune encephalopathies, especially limbic encephalitis, and related conditions. PMCID: PMC4478035 The presence of AMPA antibodies may also indicate an undiscovered tumor in the thymus, lung or breast. PMID: 23983888 The neurological symptoms associated with AMPA receptor 1 antibodies include altered mental status, convulsions, memory loss amnesia, auditory hallucinations, limbic encephalitis, abnormal behavior, schizophrenia, dizziness and hyperthermia. The neurological symptoms associated with AMPA receptor 2 antibodies include seizures, short-term memory loss, limbic encephalitis, altered mental status, chorea and facial dyskinesia. PMID: 24707504 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 2 Ab:PrThr:Pt:Ser:Ord:IF
Long Common Name
AMPAR2 Ab [Presence] in Serum by Immunofluorescence
Short Name
AMPAR2 Ab Ser Ql IF
Display Name
AMPAR2 Ab IF Ql (S)
Consumer Name Alpha Get Info
AMPAR2 antibody, Blood

Part Model Get Info

  • Component
    Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 2 Ab
    LP232463-2
    • Analyte
      Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 2 Ab
      LP232463-2
      • Component Numerator
        Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 2 Ab
        LP232463-2
        • Component Numerator Core
          Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 2
          LP229975-0
        • Component Numerator Core Suffix
          Ab
          LP20667-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    IF
    LP6323-2

Example Answer List: LL360-9

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)LA6577-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.58 (ADD)
Order vs. Observation
Both

Member of these Groups Get Info

LOINC GroupGroup Name
LG50946-9Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 2 Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Alfa-amino-3-hydroxy-5-methyl-4-isoxazolepropionát receptor 2 (AMPAR 2) Ab:Přítomnost nebo práh:Časový bod:Sérum:Ordinální:Imunofluoresecence (IF)
el-GRGreek (Greece)Υποδοχέας 2 α-αμινο-3-υδροξυ-5-μεθυλο-4-ισοξαζολοπροπιονικού οξέος Αντίσωμα:PrThr:Pt:Ορός:Ord:Ανοσοφθορισμός
Synonyms: Ord PrThr Pt SERO Ανοσοφθορισμός Αντίσωμα Ορός Υποδοχέας 2 α-αμινο-3-υδροξυ-5-μεθυλο-4-ισοξαζολοπροπιονικού οξέος
es-ESSpanish (Spain)Receptor 2 de Alfa-amino-3-hidroxi-5-metil-4-isoxazolepropionato Anticuerpos:PrThr:Punto temporal:Suero:Ord:Inmunofluorescencia (IF)
es-MXSpanish (Mexico)Receptor 2 Ab de alfa-amino-3-hidroxi-5-metil-4-isoxazolpropionato:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunofluorescencia (IF)
fr-FRFrench (France)AMPA récepteur 2 Ac:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunofluorescence
it-ITItalian (Italy)Recettore tipo 2 per alfa-amino-3-idrossi-5metil-4-isoxazolepropionato Ab:PrThr:Pt:Siero:Ord:IF
Synonyms: AMPAR2 anticorpo Immunofluorescenza (IF) Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NLDutch (Netherlands)alfa-amino-3-hydroxy-5-methyl-4-isoxazolpropionaatreceptor 2 As:aanwezigheid:moment:serum:ordinaal:immunofluorescentie
Synonyms: antistof; antilichaam IF
pl-PLPolish (Poland)Receptor 2 alfa-amino-3-hydroksy-5-metylo-4-izoksazolopropionowy Ab:granica wykrywalności:punkt w czasie:surowica:uporządkowany:immunofluorescencja
Synonyms: AMPAR2 Przeciwciała do AMPAR2
zh-CNChinese (China)Alpha-氨基-3-羟基-5-甲基-4-异噁唑丙酸受体 2 抗体:存在情况或阈值:时间点:血清:序数型:免疫荧光法
Synonyms: Ⅱ Ⅲ Ab;自身抗体 Alpha-氨基-3-羟基-5-甲基-4-异恶唑丙酸受体 2;α-氨基-3-羟基-5-甲基-4-异唑丙酸受体 2;α-氨基-3-羟基-5-甲基-4-异唑丙酸受体 2;AMPAR2 Hydroxy IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 II III OH α 三 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 叁 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 羟 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 阿尔法

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CodeSystem lookup
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