85046-1

AmpC beta-lactamase by cefoTEtan to cefoTEtan+cloxacillin inhibitory concentration ratio [Presence] by ARD gradient strip

Active

Term Description

This term is used to report the presence or absence of AmpC beta-lactamase enzymes based on inhibitory concentrations of cefotetan and cefotetan+cloxacillin. This term was created for, but is not limited in use to, bioMerieux's ETEST AmpC assay.

Part Descriptions

LP232457-4 AmpC beta-lactamase by cefoTEtan to cefoTEtan+cloxacillin inhibitory concentration ratio
AmpC beta-lactamases (AmpCs) are resistance enzymes produced by pathogenic organisms such as E. coli. AmpC enzymes hydrolyze a variety of antimicrobials, including cephalosporins, penicillins, and aztreonam. The presence of AmpC can be detected by comparing the inhibitory concentration (IC) of cefotetan, which induces AmpC, with the IC of cefotetan+cloxacillin, in which cloxacillin is an AmpC inhibitor. Source: Regenstrief LOINC

LP234471-3 Gradient strip ARD
A gradient strip is a reagent strip that contains a predefined concentration gradient of a specific antibiotic or combination of antibiotics that is used for antimicrobial susceptibility testing (AST) and antimicrobial resistance detection (ARD).
For AST, the result is reported in terms of the minimum inhibitory concentration (MIC) of a specific antimicrobial that prevents the visible growth of bacteria. In LOINC, the "Gradient strip" method is used for AST gradient strips that result in an MIC result.
For ARD, the result is reported as the presence or absence of a specific enzyme or other mechanism that confers resistance, which is determined based on comparing the inhibitory concentration (IC) of a specific antimicrobial with the IC of that antimicrobial plus a resistance inhibitor. In LOINC, the "Gradient strip ARD" method is used for ARD gradient strips, which are not intended for determining individual MIC values. Source: Regenstrief LOINC

Fully-Specified Name

Component: AmpC beta-lactamase by cefoTEtan to cefoTEtan+cloxacillin inhibitory concentration ratio
Property: PrThr
Time: Pt
System: Isolate
Scale: Ord
Method: Gradient strip ARD

Additional Names

Long Common Name: AmpC beta-lactamase by cefoTEtan to cefoTEtan+cloxacillin inhibitory concentration ratio [Presence] by ARD gradient strip
Short Name: AmpC cefo + cefo-clox IC Islt Ql Grad
Display Name: AmpC beta-lactamase by cefoTEtan to cefoTEtan+cloxacillin inhibitory concentration ratio ARD gradient strip Ql (Isol)
Consumer Name Alpha Get Info: AmpC beta-lactamase by cefoTEtan to cefoTEtan+cloxacillin inhibitory concentration ratio

Example Answer List: LL744-4

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8

Basic Attributes

Class: ABXBACT
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.58 (ADD)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Αναλογία ανασταλτικής συγκέντρωσης AmpC β-λακταμάσης από κεφοτετάνη προς κεφοτετάνη+κλοξακιλλίνη:PrThr:Pt:Απομονωμένο στέλεχος:Ord:Λωρίδα με διαβαθμίσεις ARD Synonyms: PrThr Αναλογία ανασταλτικής συγκέντρωσης AmpC β-λακταμάσης από κεφοτετάνη προς κεφοτετάνη+κλοξακιλλίνη Κεφοτετάνη Κλοξακιλλίνη
es-ES	Spanish (Spain)	AmpC beta-lactamasa para la concentración inhibitoria de cefotetan frente a la de cefotetan-cloxacilina:PrThr:Punto temporal:Aislado:Ord:Detercción de resistencia antimicrobiana por gradiente en tira.
es-MX	Spanish (Mexico)	AmpC beta-lactamasa por cefoTEtan a cefoTEtan + cociente de concentración inhibidora de cloxacilina:Presencia o umbral:Punto temporal:Aislado:Ordinal:Tira degradada para la detección de resistencia a los antimicrobianos
fr-FR	French (France)	Ratio CMI bêta lactamase AmpC céfotétan/céfotétan+cloxacilline:Présence/Seuil:Ponctuel:Isolat:Qualitatif:Bandelette graduée ARD
it-IT	Italian (Italy)	Rapporto tra la concentrazione inibitoria di AmpC-beta lattamasi del cefotetan/cefotetan+ cloxacillina:PrThr:Pt:Isolato:Ord:Striscia di gradiente ARD Synonyms: Gradiente striscia (E-test) Presenza o Soglia Punto nel tempo (episodio) Striscia di gradiente per detezione resistenza ant Suscettibilità agli antibiotici
zh-CN	Chinese (China)	头孢替坦相对于头孢替坦+克拉维酸抑菌浓度比值法 AmpC beta 内酰胺酶:存在情况或阈值:时间点:分离株:序数型:抗生素耐药性检测梯度胶条法 Synonyms: 5-甲基-3-邻氯苯基-4-异恶唑青霉素;幼氯青霉素;氯唑西林;氯洒西林;邻氯苯甲异恶唑菌霉素 ARD 梯度胶条法;E-胶条法;E-试验;E-试验法;梯度条;梯度条法;梯度板条;梯度板条法;梯度胶条;梯度胶片;梯度胶片法;E-胶条;ARD;antimicrobial resistance detection B Betalactamase Beta-内酰胺酶 B-Lactamase B-内酰胺酶 E-胶条法;E-试验;E-试验法;梯度条;梯度条法;梯度板条;梯度板条法;梯度胶条;梯度胶片;梯度胶片法;E-胶条 β β内酰胺酶 β-内酰胺酶依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型分离物;分离菌;分离菌株;隔离种群头孢双硫唑甲氧头孢替坦（头孢双硫唑甲氧）相对于（与、相对）头孢替坦（头孢双硫唑甲氧）+克拉维酸（棒酸）抑菌浓度（抑制浓度、IC）比值（比例、比、比率）法 AmpC beta 内酰胺酶（AmpC β内酰胺酶、AmpC β-内酰胺酶、AmpC βL、AmpC bL、AmpC BL、bL）;头孢吡肟相对于头孢吡肟+克拉维酸抑菌浓度比值法 AmpC BL 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类时刻;随机;随意;瞬间贝塔

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=85046-1

LOINC Copyright

Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.