Version 2.78

Part Description

LP36918-8   21-hydroxylase Ab
Adrenal enzyme steroid 21-hydroxylase (P450c21, CYP21A2) lesions lead to faulty synthesis of adrenal cortisol with frequent deficiency of aldosterone. PMID: 8478006 Cytochrome P450c21 is the essential enzyme in the synthesis of cortisol. It converts progesterone and 17 alpha-hydroxyprogesterone to 11-deoxycorticosterone and 11-doxycortisol, respectively, which in turn are needed to synthesize aldosterone and cortisol. There are two CYP21 genes on chromosome 6 that are arranged together. One that is a pseudogene (CYP21A) and one that is a functional gene (CYP21B). It is proposed that gene crossover between CYP21A and CYP21B may be one of the causes of P450c21 deficiency that ultimately leads to congenital adrenal hyperplasia. One in 10,000 births are found to have P450c21 deficiency and is the primary cause of adrenal hyperplasia. PMID: 2233746[http://www.sciencedirect.com/science/article/pii/S0006291X06005924) Source: Regenstrief LOINC

Fully-Specified Name

Component
21-Hydroxylase Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method

Additional Names

Short Name
21Hydroxylase Ab Ser Ql
Display Name
21-Hydroxylase Ab Ql (S)
Consumer Name Alpha Get Info
21-Hydroxylase antibody, Blood

Example Answer List: LL2010-8

Source: Estonian Society of Laboratory Medicine
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6
Borderline LA4259-3

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.61
Last Updated
Version 2.67
Change Reason
Changed Component from the synonym 21-Hydroxylase p450c21 Ab to 21-Hydroxylase Ab
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-MX Spanish (Mexico) 21-hidroxilasa Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:
es-ES Spanish (Spain) 21- Hidroxilasa Anticuerpos:PrThr:Punto temporal:Suero:Ord:
et-EE Estonian (Estonia) 21-hüdroksülaasi vastased antikehad:PrThr:Pt:S:Ord:
Synonyms: Järgarvuline Juhuslik Seerum
fr-CA French (Canada) 21-hydroxylase, Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:
fr-FR French (France) 21-hydroxylase anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:
fr-BE French (Belgium) 21-hydroxylase Ac:PrThr:Temps ponctuel:Sérum:Ordinal:
Synonyms: Anticorps
it-IT Italian (Italy) 21-Idrossilasi Ab:PrThr:Pt:Siero:Ord:
Synonyms: anticorpo Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) 21-hydroxylase As:aanwezigheid:moment:serum:ordinaal:
Synonyms: antistof; antilichaam
ru-RU Russian (Russian Federation) 21-Гидроксилаза Ат:PrThr:ТчкВрм:Сыв:Пор:
Synonyms: Антитело Порядковый Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) 21-Hidroksilaz Ab:MevcEşik:Zmlı:Ser:Srl:
Synonyms: Ak Mevcut
zh-CN Chinese (China) 21-羟化酶 抗体:存在情况或阈值:时间点:血清:序数型:
Synonyms: 21-羟化酶 Ab Ab;自身抗体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 氢氧酶 类固醇 21-单加氧酶 Ab 类固醇 21-单加氧酶;类固醇 21-单氧酶;类固醇 21-羟化酶 类固醇 21-单加氧酶抗体 类固醇 21-单氧酶 Ab 类固醇 21-单氧酶抗体 类固醇 21-羟化酶 Ab 类固醇 21-羟化酶抗体 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=85363-0