Version 2.77

Term Description

The results of this test are determined by immunofluorescent patterns.
Source: Regenstrief LOINC

Part Description

LP232481-4   Neutrophil membrane Ab.IgM
Antineutrophil antibodies are antibodies that bind to antigens on the surface of neutrophils. The IgG Fc receptor on the neutrophil membrane surface is the primary target for antineutrophil antibodies. It was first recognized that these antibodies were a cause of autoimmune neutropenia (AIN) in 1975. Neutropenia is separated into three categories according to the risk of infection and based on the concentration of circulating neutrophils: mild neutropenia (1000-1500 cells/uL) moderate neutropenia (500-1000 cells/uL) and severe (less than 500 cells/uL). In some AIN the neutrophil numbers are normal but some functions are compromised including their ability to influence adhesion, aggregation, chemotaxis, phagocytosis and metabolic activation. AIN has two subcategories including primary AIN and secondary AIN. In primary IAN there is no association with another pathology. Primary IAN is most common in neonates and results in moderate to severe neutropenia, rarely leads to infection and is self-limiting. Secondary IAN usually occurs following a systemic autoimmune or haemitological disease including infectious diseases, solid or haematological neoplasms, neurological diseases, bone marrow or stem cell trnasplants, kidney transplants and the use of some drugs. In light of the difficulty in detecting autoimmune antineutrophil antibodies, it is recommended that both immunofluorescent and agglutination tests be performed. PMID: 16207350 Source: Regenstrief LOINC

Fully-Specified Name

Component
Neutrophil membrane Ab.IgM
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IF

Additional Names

Short Name
Neutrophil membrane IgM Ser Ql IF
Display Name
Neutrophil membrane IgM IF Ql (S)
Consumer Name Alpha Get Info
Neutrophil membrane IgM antibody, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.61
Last Updated
Version 2.61
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Membrana neutrófila IgM:PrThr:Punto temporal:Suero:Ord:Inmunofluorescencia (IF)
es-MX Spanish (Mexico) IgM de membrana de neutrófilos:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunofluorescencia (IF)
fr-FR French (France) Membrane des polynucléaires neutrophiles anticorps IgM:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunofluorescence
it-IT Italian (Italy) Membrana neutrofili Ab.IgM:PrThr:Pt:Siero:Ord:IF
Synonyms: Anticorpi IgM anticorpo Immunofluorescenza (IF) Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) neutrofiel membraan As.IgM:aanwezigheid:moment:serum:ordinaal:immunofluorescentie
Synonyms: antistof; antilichaam IF
pl-PL Polish (Poland) Neutrofil błona Ab.IgM:granica wykrywalności:punkt w czasie:surowica:półilościowy:immunofluorescencja
Synonyms: Błona neutrofila IgM Neutrofil Przeciwciała IgM do błony neutrofili
zh-CN Chinese (China) 嗜中性粒细胞膜 抗体.IgM:存在情况或阈值:时间点:血清:序数型:免疫荧光法
Synonyms: Ab.IgM;IgM;抗体 IgM Ab;自身抗体 IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 PMN;中性;中性白细胞;中性粒细胞;嗜中性;嗜中性白细胞;多形核;多形核白细胞;多形核粒细胞;多形核粒细胞（PMN） 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫球蛋白 M 嗜中性粒细胞（中性、中性粒、中性粒细胞、嗜中性、Neu）膜（细胞膜、胞膜） 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

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