Neutrophil membrane IgM Ab [Presence] in Serum by Immunofluorescence
The results of this test are determined by immunofluorescent patterns.
Source: Regenstrief LOINC
LP232481-4 Neutrophil membrane Ab.IgM
Antineutrophil antibodies are antibodies that bind to antigens on the surface of neutrophils. The IgG Fc receptor on the neutrophil membrane surface is the primary target for antineutrophil antibodies. It was first recognized that these antibodies were a cause of autoimmune neutropenia (AIN) in 1975. Neutropenia is separated into three categories according to the risk of infection and based on the concentration of circulating neutrophils: mild neutropenia (1000-1500 cells/uL) moderate neutropenia (500-1000 cells/uL) and severe (less than 500 cells/uL). In some AIN the neutrophil numbers are normal but some functions are compromised including their ability to influence adhesion, aggregation, chemotaxis, phagocytosis and metabolic activation. AIN has two subcategories including primary AIN and secondary AIN. In primary IAN there is no association with another pathology. Primary IAN is most common in neonates and results in moderate to severe neutropenia, rarely leads to infection and is self-limiting. Secondary IAN usually occurs following a systemic autoimmune or haemitological disease including infectious diseases, solid or haematological neoplasms, neurological diseases, bone marrow or stem cell trnasplants, kidney transplants and the use of some drugs. In light of the difficulty in detecting autoimmune antineutrophil antibodies, it is recommended that both immunofluorescent and agglutination tests be performed. PMID: 16207350 Source: Regenstrief LOINC
- Neutrophil membrane Ab.IgM
- Short Name
- Neutrophil membrane IgM Ser Ql IF
- Display Name
- Neutrophil membrane IgM IF Ql (S)
- Consumer Name Alpha Get Info
- Neutrophil membrane IgM antibody, Blood
Example Answer List: LL360-9Source: Regenstrief Institute
|PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)||LA6576-8|
|NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)||LA6577-6|
- First Released
- Version 2.61
- Last Updated
- Version 2.61
- Order vs. Observation
Language Variants Get Info
|es-ES||Spanish (Spain)||Membrana neutrófila IgM:
|es-MX||Spanish (Mexico)||IgM de membrana de neutrófilos:
|fr-FR||French (France)||Membrane des polynucléaires neutrophiles anticorps IgM:
|it-IT||Italian (Italy)||Membrana neutrofili Ab.IgM:
Synonyms: Anticorpi IgM anticorpo Immunofluorescenza (IF) Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
|nl-NL||Dutch (Netherlands)||neutrofiel membraan As.IgM:
|pl-PL||Polish (Poland)||Neutrofil błona Ab.IgM:
Synonyms: Błona neutrofila IgM Neutrofil Przeciwciała IgM do błony neutrofili
|zh-CN||Chinese (China)||嗜中性粒细胞膜 抗体.IgM:
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