85367-1
Neutrophil membrane IgG Ab [Presence] in Serum by Immunofluorescence
Active
Term Description
The results of this test are determined by immunofluorescent patterns.
Part Description
LP232482-2 Neutrophil membrane Ab.IgG
Antineutrophil antibodies are antibodies that bind to antigens on the surface of neutrophils. The IgG Fc receptor on the neutrophil membrane surface is the primary target for antineutrophil antibodies. It was first recognized that these antibodies were a cause of autoimmune neutropenia (AIN) in 1975. Neutropenia is separated into three categories according to the risk of infection and based on the concentration of circulating neutrophils: mild neutropenia (1000-1500 cells/uL) moderate neutropenia (500-1000 cells/uL) and severe (less than 500 cells/uL). In some AIN the neutrophil numbers are normal but some functions are compromised including their ability to influence adhesion, aggregation, chemotaxis, phagocytosis and metabolic activation. AIN has two subcategories including primary AIN and secondary AIN. In primary IAN there is no association with another pathology. Primary IAN is most common in neonates and results in moderate to severe neutropenia, rarely leads to infection and is self-limiting. Secondary IAN usually occurs following a systemic autoimmune or haemitological disease including infectious diseases, solid or haematological neoplasms, neurological diseases, bone marrow or stem cell trnasplants, kidney transplants and the use of some drugs. In light of the difficulty in detecting autoimmune antineutrophil antibodies, it is recommended that both immunofluorescent and agglutination tests be performed. PMID: 16207350
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Neutrophil membrane Ab.IgG:
PrThr: Pt: Ser: Ord: IF - Long Common Name
- Neutrophil membrane IgG Ab [Presence] in Serum by Immunofluorescence
- Short Name
- Neutrophil membrane IgG Ser Ql IF
- Display Name
- Neutrophil membrane IgG IF Ql (S)
- Consumer Name Alpha Get Info
- Neutrophil membrane IgG antibody, Blood
Part Model Get Info
- Component
- Neutrophil membrane Ab.IgG
LP232482-2
- Analyte
- Neutrophil membrane Ab.IgG
LP232482-2
- Component Numerator
- Neutrophil membrane Ab.IgG
LP232482-2
- Component Numerator Core
- Neutrophil membrane
LP232480-6
- Component Numerator Core Suffix
- Ab.IgG
LP32401-9
- Component Denominator
- NULL
- Component Denominator Core
- NULL
- Component Denominator Core Suffix
- NULL
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- PrThr
LP217195-9
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- Ser
LP7567-3
- System Core
- Ser
LP7567-3
- Super System
- NULL
- Scale
- Ord
LP7751-3
- Method
- IF
LP6323-2
Example Answer List: LL360-9
Source: Regenstrief Institute| Answer | Code | Score | Answer ID |
|---|---|---|---|
| PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61 (ADD)
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Neutrofily membrána.IgG: |
| el-GR | Greek (Greece) | Μεμβράνη ουδετερόφιλου Αντισώματα IgG: Synonyms: Ord PrThr Pt SERO Ανοσοσφαιρίνη G Ανοσοφθορισμός Αντίσωμα Αντισώματα IgG Μεμβράνη ουδετερόφιλου Ορός Ουδετερόφιλο |
| es-ES | Spanish (Spain) | Membrana neutrófila IgG: |
| es-MX | Spanish (Mexico) | Membrana de neutrófilos IgG: |
| fr-FR | French (France) | Membrane des polynucléaires neutrophiles Ac IgG: |
| it-IT | Italian (Italy) | Membrana neutrofili Ab.IgG: Synonyms: anticorpi IgG anticorpo Immunofluorescenza (IF) Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | neutrofiel membraan As.IgG: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Neutrofil błona Ab.IgG: Synonyms: Błona neutrofila IgG Neutrofil przeciwciała IgG Przeciwciała IgG do błony neutrofili |
| zh-CN | Chinese (China) | 嗜中性粒细胞膜 抗体.IgG: Synonyms: Ab.IgG; |
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Third Party Copyright
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://