85628-6

Neisseria meningitidis sodC gene [Presence] in Specimen by NAA with probe detection

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Part Descriptions

LP248050-9 Neisseria meningitidis sodC gene
Neisseria meningitides (Nm) is a species of gram-negative, aerobic bacteria. It is a commensal and pathogen only of humans, and can be carried asymptomatically in the nasopharynx. When found in cerebrospinal fluid it is the causative agent of cerebrospinal meningitis (meningitis, meningococcal). Nm can also be found in venereal discharges and blood. At least 13 serogroups have been described based on antigenic differences in the capsular polysaccharides; the ones causing most meningitis infections being A, B, C, Y, and W-135. Outbreaks caused by serogroup X meningococci have also been reported. Each serogroup can be further classified by serotype, serosubtype, and immunotype. (NLM, MeSH 2006) The two targets most frequently used in real-time PCR assays to identify Nm are the capsule transport gene (ctrA) and the Cu-An superoxide dismutase gene (sodC). sodC is found only in Nm and not in other species of Neisseria. sodC is highly sensitive and specific for the detection of Nm regardless of whether capsule genes are present or absent. ctrA is likely the target gene most often used to identify Nm, but because it is prone to rearrangement it does not detect roughly 16% of patients with Nm. PMID: 21573213 Source: Regenstrief LOINC

LP248050-9 Neisseria meningitidis sodC gene
Neisseria meningitidis is identified based on the species-specific targets sodC and ctrA. Individual Neisseria meningitidis serogroups are identified based on their serogroup-specific genes for capsule biosynthesis. Serogroups and the genes that identify them are as follows:
N. meningitidis serogroup A: sacB
N. meningitidis serogroup B: synD
N. meningitidis serogroup C: synE
N. meningitidis serogroup w135: synG
N. meningitidis serogroup X: xcbB
N. meningitidis serogroup Y: synF
[https://www.cdc.gov/meningitis/lab-manual/chpt10-pcr.html] Source: Regenstrief LOINC

Fully-Specified Name

Component: Neisseria meningitidis sodC gene
Property: PrThr
Time: Pt
System: XXX
Scale: Ord
Method: Probe.amp.tar

Additional Names

Short Name: N mening sodC Spec Ql NAA+probe
Display Name: N. meningitidis sodC gene NAA+probe Ql (Specimen)
Consumer Name Alpha Get Info: Neisseria meningitidis sodC gene, Specimen

Example Answer List: LL2009-0

Source: ARUP Laboratories

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6
EquivocalCopyright http://snomed.info/sct ID:42425007 Equivocal (qualifier value)			LA11885-3

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.69
Order vs. Observation: Both

Member of these Groups Get Info

LOINC Group	Group Name
LG41618-6	Neisseria meningitidis

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	Neisseria meningitidis sodC-Gen:Nachweis oder Schwellenwert:Zeitpunkt:XXX:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-ES	Spanish (Spain)	Gen sodC de Neisseria meningitidis:PrThr:Punto temporal:XXX:Ord:Sonda con amplificación dirigida
es-MX	Spanish (Mexico)	Gen sodC de Neisseria meningitidis:Presencia o umbral:Punto temporal:XXX:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR	French (France)	Neisseria meningitidis sodC gène:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:PCR amplification de cible
it-IT	Italian (Italy)	Neisseria meningitidis, gene sodC:PrThr:Pt:XXX:Ord:Sonda.amp.tar Synonyms: Gene sodC di Neisseria meningitidis Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	Neisseria meningitidis sodC-gen:aanwezigheid:moment:XXX:ordinaal:probe-detectie Synonyms: probe.amp.tar
zh-CN	Chinese (China)	脑膜炎奈瑟菌 sodC 基因:存在情况或阈值:时间点:XXX:序数型:探针法.基因扩增.靶向 Synonyms: 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间流脑;流行性脑脊髓膜炎;脑膜炎双球菌;脑膜炎双球菌性脑膜炎;脑膜炎奈瑟氏双球菌;脑膜炎奈瑟氏球菌;脑膜炎奈瑟氏菌;脑膜炎球菌;脑膜炎球菌性脑膜炎经过扩增的脱氧核糖核酸探针遗传基因;遗传因子;吉恩;生物基因

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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.