LOINC
Version 2.67

85824-1Carbapenem resistance blaIMP gene [Presence] by NAA with probe detectionDiscouraged

Status Information

Status
Discouraged
Comment
Recommend using the term with System Isolate/Specimen and Method Molgen that aligns with the new LOINC model for molecular resistance testing that was approved by Laboratory LOINC Committee in June 2018
Map-To Long Common Name Mapping Guidance
85498-4 Carbapenem resistance blaIMP gene [Presence] by Molecular method

Term Description

This test reports the presence of the IMP bacterial carbapenemase resistance type gene in gram negative bacterial isolates. This term was created for, but is not limited in use to, the submitter's modified protocol for the Check-Points Check-MDR CT103XL assay.
Source: Regenstrief LOINC

Part Descriptions

LP248294-3   Bacterial carbapenem resistance blaIMP gene
Plasmid-mediated IMP-type carbapenemases are currently known to have 17 varieties. Studies have revealed its establishment in Japan in the 1990s in enteric Gram-negative organisms, Pseudomonas species and Acinetobacter species. IMP genes usually co-exist with other resistance genes resulting in multi-drug resistance.
Studies have shown that a high percentage of patients with immunodeficiency and drug resistant nosocomial infections are infected with a VIM or IMP producing organism, particularly when the organism identified is pseudomonas aeruginosa. The two genes are often present together although they can also be present individually. Identifying the presence of these genes is important in monitoring drug resistance and determining the best antibiotic therapy methods.
[PMID: 27563634] [PMID: 28085553] Source: Regenstrief LOINC

LP265773-4   Bacterial ABXBACT probe.amp.tar
PCR-based Methods for bacterial susceptibility are similar to genotyping for viral susceptibility, in that resistance or susceptibility is inferred based on the presence or absence of specific genetic information that is known to encode resistance to a specific antibiotic or group of antibiotics. For bacteria, resistance is often conferred by genes that are carried on plasmids, which can be transferred from one species to another. These genes encode proteins that specifically inhibit certain antibiotics, such as carbapenems or aminoglycosides. Source: Regenstrief LOINC

Fully-Specified Name

Component
Bacterial carbapenem resistance blaIMP gene
Property
PrThr
Time
Pt
System
Isolate
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
blaIMP Islt Ql NAA+probe
Display Name
Carbapenem resistance blaIMP gene NAA+probe Ql (Isol)

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.61
Last Updated
Version 2.67
Order vs. Observation
Observation

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Language Variants Get Info

zh-CNChinese (CHINA)
细菌碳青霉烯类耐药 blaIMP 基因:存在情况或阈值:时间点:分离株:序数型:探针法.基因扩增.靶向
nl-NLDutch (NETHERLANDS)
bacteriële carbapenemresistentie blaIMP-gen:aanwezigheid:moment:isolaat:ordinaal:moleculaire techniek (PCR)
fr-FRFrench (FRANCE)
Résistance bactérienne aux carbapénèmases blaIMP gène:Présence/Seuil:Ponctuel:Isolat:Qualitatif:PCR amplification de cible
it-ITItalian (ITALY)
Resistenza batterica ai carbapenemici, gene blaIMP:PrThr:Pt:Isolato:Ord:Sonda.amp.tar
es-ESSpanish (SPAIN)
gen bacteriano blaIMP resistente a carbapenem:PrThr:Punto temporal:Aislado:Ord:Sonda con amplificación dirigida

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=85824-1