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Term Description

Sample types for this test include formalin-fixed, paraffin-embedded tissue samples, frozen samples, or cell smears/cultures.

Part Description

LP182479-8   Porcine epidemic diarrhea virus
Porcine Epidemic Diarrhea Virus (PEDv) is a large-enveloped RNA virus, which is a member of the genus Alphacoronavirus within the Coronaviridae family. The complete PEDv genome consists of 5 gene segments: open reading frame 1 (ORF1), spike (S), envelope (E), membrane (M), and nucleocapsid (N). It is encapsulated by a single N protein. The S protein contributes to the stimulation of neutralizing antibodies in the infected host. Its association to adapted growth in vitro and attenuation in vivo lends itself to use for genetic comparison among PEDV isolates and effective vaccines. The M protein is required for assembly and can also induce the production of virus-neutralizing antibodies. The E protein contributes to coronavirus budding. The N protein has functions associated with viral replication and pathogenesis.
PEDv causes viral enteritis, which leads to the destruction of villus enterocytes in pigs of all ages. It is spread by the ingestion of feces from infected pigs, resulting in vomiting, watery diarrhea, dehydration, and high mortality, especially in nursery piglets. Disease caused by PEDv is clinically similar to that caused by Transmissible gastroenteritis coronavirus (TGEV) PMID: 26689811
At least two PEDv strains have been identified in the USA: the US PEDv prototype and S INDEL variant. The INDEL variant PEDv strain has insertions and deletions (INDELs) in the spike (S) gene. PMID: 25279722 The INDEL strain is related to milder clinical signs than prototype strains. PMID: 24750580 PMID: 26748596 The genomic differences in the S gene between the US PEDv prototype and INDEL variant may be responsible for the virulence differences. Potential targets when testing for PEDv RNA include the nucleocapsid protein (N) gene and the ~2500 bp fragment of the S-gene. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Porcine epidemic diarrhea virus:PrThr:Pt:Tiss:Ord:Immune stain
Long Common Name
Porcine epidemic diarrhea virus [Presence] in Tissue by Immune stain
Short Name
PEDv Tiss Ql ImStn
Display Name
Porcine epidemic diarrhea virus Immune stain Ql (Tiss)
Consumer Name Alpha Get Info
Porcine Epidemic Diarrhea virus, Tissue

Part Model Get Info

  • Component
    Porcine epidemic diarrhea virus
    LP182479-8
    • Analyte
      Porcine epidemic diarrhea virus
      LP182479-8
      • Component Numerator
        Porcine epidemic diarrhea virus
        LP182479-8
        • Component Numerator Core
          Porcine epidemic diarrhea virus
          LP182479-8
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Tiss
    LP7641-6
    • System Core
      Tiss
      LP7641-6
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Immune stain
    LP6333-1

Example Answer List: LL360-9

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)LA6577-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.61
Last Updated
Version 2.63 (MAJ)
Change Reason
Updated System from "Tissue" to "Tiss" to be consistent with other laboratory tissue terms.
Order vs. Observation
Observation

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Virus epidemické prasečí průjmové nemoci (PED):Přítomnost nebo práh:Časový bod:Tkáně a stěry:Ordinální:Imunobarvení
el-GRGreek (Greece)Ιός επιδημικής διάρροιας των χοίρων:PrThr:Pt:Ιστός:Ord:Ανοσολογική χρώση
Synonyms: MICRO Ord PrThr Pt Ανοσολογική χρώση Ιός Ιός επιδημικής διάρροιας των χοίρων Ιστός Των χοίρων
es-ESSpanish (Spain)Virus de la diarrea epidémica porcina:PrThr:Punto temporal:Tejido:Ord:Tinción de inmunohistoquímica
es-MXSpanish (Mexico)Virus de la diarrea epidémica porcina:Presencia o umbral:Punto temporal:Tejido y frotis:Ordinal:Mancha inmune
it-ITItalian (Italy)Virus della diarrea epidemica suina:PrThr:Pt:Tessuto:Ord:Colorazione immunologica
Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Tessuto & Strisci Virus PED
nl-NLDutch (Netherlands)'porcine' epizoötisch diarreevirus:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:immunokleuring
Synonyms: epizoötisch diarreevirus van varken porcine
pl-PLPolish (Poland)Wirus epidemicznej biegunki świń:granica wykrywalności:punkt w czasie:tkanka i rozmazy:uporządkowany:barwienie immunohistochemiczne
ru-RURussian (Russian Federation)Свиная эпидемическая диаррея вирус:PrThr:ТчкВрм:Тк:Пор:Иммуногистохимическая окраска
Synonyms: Порядковый Ткань и мазки Точка во времени;Момент
tr-TRTurkish (Turkey)Porsin epidemik diyare virüsü:MevcEşik:Zmlı:Doku:Srl:İmmün boyama
Synonyms: Mevcut
zh-CNChinese (China)猪流行性腹泻病毒:存在情况或阈值:时间点:组织与涂片:序数型:免疫染色法
Synonyms: 下痢;泄泻;下利;泻肚 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫染色;免疫组化;免疫组化染色;免疫组化染色法;免疫组化法;免疫组织化学染色;免疫组织化学染色法;细胞免疫染色;细胞免疫染色法 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 染法 染色方法 染色法 猪传染性腹泻病毒;PEDv 猪的 猪科 猪科的 着色 着色方法 着色法

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=86202-9