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Term Description

This term is used to report the titer of IgG antibodies against Porcine epidemic virus (PEDv) based on immunofluorescence staining pattern. IgG antibodies to PEDv are typically be detected 7 to 14 days following exposure. Samples are compared to positive and negative controls. If cells fluoresce brilliant blue-green color against a background of non-infected cells, then the sample is considered positive; If cells do not fluoresce brilliantly but may show background non-specific fluorescence, then the sample is considered negative.; If cells fluoresce weakly and is not background fluorescence, then the sample is considered suspect. If high background fluorescence does not allow for an accurate determination to be made, then the sample is considered inconclusive. Titers that are equal to or greater than 1:40 are considered positive.

Part Description

LP182479-8   Porcine epidemic diarrhea virus
Porcine Epidemic Diarrhea Virus (PEDv) is a large-enveloped RNA virus, which is a member of the genus Alphacoronavirus within the Coronaviridae family. The complete PEDv genome consists of 5 gene segments: open reading frame 1 (ORF1), spike (S), envelope (E), membrane (M), and nucleocapsid (N). It is encapsulated by a single N protein. The S protein contributes to the stimulation of neutralizing antibodies in the infected host. Its association to adapted growth in vitro and attenuation in vivo lends itself to use for genetic comparison among PEDV isolates and effective vaccines. The M protein is required for assembly and can also induce the production of virus-neutralizing antibodies. The E protein contributes to coronavirus budding. The N protein has functions associated with viral replication and pathogenesis.
PEDv causes viral enteritis, which leads to the destruction of villus enterocytes in pigs of all ages. It is spread by the ingestion of feces from infected pigs, resulting in vomiting, watery diarrhea, dehydration, and high mortality, especially in nursery piglets. Disease caused by PEDv is clinically similar to that caused by Transmissible gastroenteritis coronavirus (TGEV) PMID: 26689811
At least two PEDv strains have been identified in the USA: the US PEDv prototype and S INDEL variant. The INDEL variant PEDv strain has insertions and deletions (INDELs) in the spike (S) gene. PMID: 25279722 The INDEL strain is related to milder clinical signs than prototype strains. PMID: 24750580 PMID: 26748596 The genomic differences in the S gene between the US PEDv prototype and INDEL variant may be responsible for the virulence differences. Potential targets when testing for PEDv RNA include the nucleocapsid protein (N) gene and the ~2500 bp fragment of the S-gene. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Porcine epidemic diarrhea virus Ab.IgG:Titr:Pt:Ser:SemiQn:IF
Long Common Name
Porcine epidemic diarrhea virus IgG Ab [Titer] in Serum by Immunofluorescence
Short Name
PEDv IgG Titr Ser IF
Display Name
Porcine epidemic diarrhea virus IgG IF (S) [Titer]
Consumer Name Alpha Get Info
Porcine Epidemic Diarrhea virus IgG antibody, Blood

Part Model Get Info

  • Component
    Porcine epidemic diarrhea virus Ab.IgG
    LP248606-8
    • Analyte
      Porcine epidemic diarrhea virus Ab.IgG
      LP248606-8
      • Component Numerator
        Porcine epidemic diarrhea virus Ab.IgG
        LP248606-8
        • Component Numerator Core
          Porcine epidemic diarrhea virus
          LP182479-8
        • Component Numerator Core Suffix
          Ab.IgG
          LP32401-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Titr
    LP6881-9
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    SemiQn
    LP436123-6
  • Method
    IF
    LP6323-2

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.61
Last Updated
Version 2.75 (MAJ)
Order vs. Observation
Observation

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Virus epidemické prasečí průjmové nemoci (PED) IgG:Arbitrární koncentrace (titr):Časový bod:Sérum:Semikvantitativní:Imunofluoresecence (IF)
el-GRGreek (Greece)Ιός επιδημικής διάρροιας των χοίρων Αντισώματα IgG:Titr:Pt:Ορός:Ημιποσοτική:Ανοσοφθορισμός
Synonyms: MICRO Pt Titr Ανοσοσφαιρίνη G Ανοσοφθορισμός Αντίσωμα Αντισώματα IgG Ημιποσοτική Ιός Ιός επιδημικής διάρροιας των χοίρων Ορός Των χοίρων
es-ESSpanish (Spain)Virus de la diarrea epidémica porcina IgG:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:Inmunofluorescencia (IF)
Synonyms: Semicuantitativo
es-MXSpanish (Mexico)Virus de la diarrea epidémica porcina Ab.IgG:Título:Punto temporal:Suero:Cuantitativo:Inmunofluorescencia (IF)
it-ITItalian (Italy)Virus della diarrea epidemica suina Ab.IgG:Titr:Pt:Siero:SemiQn:IF
Synonyms: anticorpi IgG anticorpo Immunofluorescenza (IF) Microbiologia Punto nel tempo (episodio) Siero Titolo Virus PED
nl-NLDutch (Netherlands)'porcine' epizoötisch diarreevirus As.IgG:titer:moment:serum:semikwantitatief:immunofluorescentie
Synonyms: antistof; antilichaam epizoötisch diarreevirus van varken IF porcine
pl-PLPolish (Poland)Wirus epidemicznej biegunki świń Ab.IgG:miano:punkt w czasie:surowica:półilościowy:immunofluorescencja
Synonyms: IgG przeciwciała IgG
zh-CNChinese (China)猪流行性腹泻病毒 抗体.IgG:滴定度:时间点:血清:半定量型:免疫荧光法
Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 下痢;泄泻;下利;泻肚 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 免疫球蛋白 G 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 猪传染性腹泻病毒;PEDv 猪的 猪科 猪科的

Example Units

UnitSource
{titer}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=86219-3