86857-0
Flavivirus neutralizing antibody [Presence] in Specimen by Neutralization test
Active
Term Description
Qualitative result for detection of Flavivirus neutralizing antibodies in clinical specimens.
Source: Regenstrief LOINC
Part Descriptions
LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method.
Source: Regenstrief LOINC
LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Flavivirus Ab.Neut
- Property
- PrThr
- Time
- Pt
- System
- XXX
- Scale
- Ord
- Method
- Neut
Additional Names
- Short Name
- Flavivirus NAb Spec Ql Nt
- Display Name
- Flavivirus neut ab Neut test Ql (Specimen)
- Consumer Name Alpha Get Info
- Flavivirus neutralizing antibody, Specimen
Example Answer List: LL2009-0
Source: ARUP Laboratories| Answer | Code | Score | Answer ID |
|---|---|---|---|
| PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 | ||
| EquivocalCopyright http://snomed.info/sct ID:42425007 Equivocal (qualifier value) | LA11885-3 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.69
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Flavivirus Anticuerpos antineutrófilos: |
| es-MX | Spanish (Mexico) | Flavivirus Ab.Neut: |
| fr-FR | French (France) | Flavivirus Ac neutralisant: |
| fr-CA | French (Canada) | Flavivirus Ac.neut: |
| it-IT | Italian (Italy) | Flavivirus Ab.Neut: Synonyms: anticorpo Microbiologia Presenza o Soglia Punto nel tempo (episodio) Test di neutralizzazione |
| nl-NL | Dutch (Netherlands) | Flavivirus As.neutraliserend: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Flawiwirus Ab.Neutralizujące: Synonyms: Flawiwirus Przeciwciała do Flawiwirusa Przeciwciała neutralizujące do Flawiwirusa |
| zh-CN | Chinese (China) | 黄病毒 抗体.中和: Synonyms: Ab; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=86857-0
Third Party Copyright
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LOINC Copyright
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