86904-0
Carboxyhemoglobin/Hemoglobin.total in Arterial blood by Pulse oximetry
Active
Term Description
Used to report the carboxyhemoglobin level as a percent of the total hemoglobin using pulse oximetry. Note that conventional pulse oximeters are not used to measure carboxyhemoglobin because they use two wavelengths of light that does not allow distinction between carboxyhemoglobin, methemoglobin, and oxyhemoglobin. However, newer pulse oximeters use multiple wavelengths (e.g., seven, eight or twelve) that allow separate measurement of carboxyhemoglobin. PMID: 21459480
Part Description
LP21418-6 Carboxyhemoglobin
Carboxyhemoglobin, a complex of hemoglobin and carbon monoxide, is a marker of exposure to inhaled carbon monoxide (CO). CO gas is produced from almost any fire as the result of incomplete combustion to CO2, and the normal individual will have about 1 or 2 % of their hemoglobin in the form of carboxyhemoglobin, and up to 5% depending on environmental circumstances. Smokers can have levels as high as 10% or even higher. Poisoning with CO generally results from improperly vented furnaces, automobile exhaust, and fires, with carboxyhemoglobin:hemoglobin ratios of 10-30% found in symptomatic individuals and 30-90% in fatalities. With a 230 fold greater affinity, inhaled CO avidly replaces oxygen at its hemoglobin binding site. In addition, replacing even one of the 4 sites of the hemoglobin tetramer with CO prevents dissociation of the remaining 3 oxygen moieties to tissue (known as left shift of O2 dissociation curve). As a result, hemoglobin remains red and skin color is rosy despite physiologic anoxia. Although measuring carboxyhemoglobin can confirm carbon monoxide poisoning, the level does not always correlate with the clinical picture; carbon monoxide poisoning involves other mechanisms as well, including binding to myoglobin, cytochrome oxidase, and direct effects on the central nervous system.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Carboxyhemoglobin/Hemoglobin.total
- Property
- MFr
- Time
- Pt
- System
- BldA
- Scale
- Qn
- Method
- Pulse oximetry
Additional Names
- Long Common Name
- Carboxyhemoglobin/Hemoglobin.total in Arterial blood by Pulse oximetry
- Short Name
- COHgb % BldA PulseOx
Basic Attributes
- Class
- PULM
- Type
- Clinical
- First Released
- Version 2.63
- Last Updated
- Version 2.63 (ADD)
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Carboxyhämoglobin/Hämoglobin.gesamt: Synonyms: COHb; |
el-GR | Greek (Greece) | Καρβοξυαιμοσφαιρίνη/Αιμοσφαιρίνη.ολική: Synonyms: MFr Αιμοσφαιρίνη Καρβοξυαιμοσφαιρίνη |
es-ES | Spanish (Spain) | Carboxihemoglobina/Hemoglobina.total: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Carboxihemoglobina / Hemoglobina total: |
fr-CA | French (Canada) | Carboxyhémoglobine/Hémoglobine.totale: |
fr-BE | French (Belgium) | Carboxyhémoglobine/Hémoglobine.totale: Synonyms: Hb Hb.totale HbCO |
it-IT | Italian (Italy) | Carbossiemoglobina/Emoglobina.totale: Synonyms: Frazione di massa Gestione ventilazione polmonare Punto nel tempo (episodio) Sangue arterioso |
nl-NL | Dutch (Netherlands) | carboxyhemoglobine/hemoglobine.totaal: Synonyms: zuurstofsaturatiemeting |
pl-PL | Polish (Poland) | Karboksyhemoglobina/hemoglobina całkowita: Synonyms: Karboksyhemoglobina Karboksyhemoglobina/Hemoglobina całkowita |
ru-RU | Russian (Russian Federation) | Карбоксигемоглобин/Гемоглобин.общий: Synonyms: Количественный Кровь артериальная Массовая доля Оксигемометрия; |
tr-TR | Turkish (Turkey) | Karboksihemoglobin/Hemoglobin.total: |
zh-CN | Chinese (China) | 碳氧血红蛋白/血红蛋白.总计: Synonyms: CO 血红蛋白; |
Example Units
Unit | Source |
---|---|
% | Example UCUM Units |
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