87725-8

Cytomegalovirus IgM Ab [Presence] in Serum or Plasma from Donor by Immunoassay

Active

Part Description

LP14255-1 Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html] Source: Regenstrief LOINC

Fully-Specified Name

Component: Cytomegalovirus Ab.IgM
Property: PrThr
Time: Pt
System: Ser/Plas^Donor
Scale: Ord
Method: IA

Additional Names

Short Name: CMV IgM SerPl Donr Ql IA
Display Name: CMV IgM IA Ql (S/P donor)
Consumer Name Alpha Get Info: Cytomegalovirus (CMV) IgM antibody, Donor Blood

Example Answer List: LL2009-0

Source: ARUP Laboratories

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6
EquivocalCopyright http://snomed.info/sct ID:42425007 Equivocal (qualifier value)			LA11885-3

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.63
Last Updated: Version 2.63
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	Cytomegalie-Virus Ak.IgM:Nachweis oder Schwellenwert:Zeitpunkt:Serum oder Plasma^Donor:Ordinal:Immunoassay Synonyms: CMV
es-ES	Spanish (Spain)	Citomegalovirus IgM:PrThr:Punto temporal:Suero o Plasma^donante:Ord:IA
es-MX	Spanish (Mexico)	Citomegalovirus Ab.IgM:Presencia o umbral:Punto temporal:Suero o plasma ^ Donante:Ordinal:Inmunoensayo
et-EE	Estonian (Estonia)	Tsütomegaloviirus antikehad.IgM:PrThr:Pt:S/P^doonor:Ord:IA Synonyms: Immuunglobuliin M Järgarvuline Juhuslik Plasma Seerum Seerum või plasma
fr-CA	French (Canada)	Cytomégalovirus, IgM:Présence-Seuil:Temps ponctuel:Sérum/Plasma^Donneur:Ordinal:IA
fr-FR	French (France)	Cytomégalovirus Ac IgM:Présence/Seuil:Ponctuel:Sérum/Plasma du donneur:Qualitatif:Immunoanalyse
fr-BE	French (Belgium)	Cytomégalovirus Anticorps. IgM:PrThr:Temps ponctuel:Sérum/Plasma^Donneur:Ordinal:IA Synonyms: Anticorps CMV
it-IT	Italian (Italy)	Citomegalovirus Ab.IgM:PrThr:Pt:Siero/Plasma^donatore:Ord:IA Synonyms: Anticorpi IgM anticorpo Immunoassay Microbiologia Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL	Dutch (Netherlands)	Cytomegalovirus As.IgM:aanwezigheid:moment:serum of plasma^donor:ordinaal:immunoassay Synonyms: antistof; antilichaam IA
pl-PL	Polish (Poland)	Wirus cytomegalii Ab.IgM:granica wykrywalności:punkt w czasie:surowica lub osocze^dawca:półilościowy:metoda immunologiczna Synonyms: Cytomegalowirus IgM Przecwciała do cytomegalowirusa Przecwciała IgM do cytomegalowirusa
ru-RU	Russian (Russian Federation)	Цитомегаловирус Ат.IgM:PrThr:ТчкВрм:Сыв/Плаз^донор:Пор:IA Synonyms: Антитело Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	Cytomegalovirus Ab.IgM:MevcEşik:Zmlı:Ser/Plaz^verici:Srl:İA Synonyms: Ak Ak.IgM İmmünölçüm, immünoassay Mevcut
zh-CN	Chinese (China)	巨细胞病毒抗体.IgM:存在情况或阈值:时间点:血清/血浆^供体:序数型:免疫测定法 Synonyms: Ab.IgM;IgM;抗体 IgM Ab;自身抗体 CMV Ab CMV Ab.IgM CMV IgM CMV 抗体 CMV 抗体.IgM CMV;涎腺病毒;细胞巨化病毒;细胞肥大病毒供血者;捐献者;捐赠者;给予体;给体;超系统 - 供体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验免疫球蛋白 M 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）巨细胞病毒 Ab 巨细胞病毒 Ab.IgM 巨细胞病毒 IgM 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）时刻;随机;随意;瞬间血清/血浆^捐赠者血清或血浆

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=87725-8

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

LOINC Copyright

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.