87820-7

Zolpidem [Presence] in Saliva (oral fluid) by Screen method

Active

Part Descriptions

LP17255-8   Zolpidem
Zolpidem is a prescription medication used for the short-term treatment of insomnia, as well as some brain disorders. It is a short-acting nonbenzodiazepine hypnotic that potentiates gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, by binding to gamma-aminobutyric acid (GABAA) receptors at the same location as benzodiazepines. Trade names of zolpidem include Adormix, Ambien, Ambien CR, Edluar, Zolpimist, Damixan, Hypnogen, Ivedal, Lioran, Myslee, Nasen, Nytamel, Sanval, Somidem, Stilnoct, Stilnox, Stilnox CR, Sucedal, Zoldem, Zolnod and Zolpihexal.

Zolpidem has not adequately demonstrated effectiveness in maintaining sleep. Its hypnotic effects are similar to those of the benzodiazepine class of drugs, but it is molecularly distinct from the classical benzodiazepine molecule and is classified as an imidazopyridine. Flumazenil, a benzodiazepine receptor antagonist, which is used for benzodiazepine overdose, can also reverse zolpidem's sedative/hypnotic and memory impairing effects. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP7565-7   Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583 Source: Regenstrief LOINC

LP262420-5   Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583 Source: Regenstrief LOINC

Fully-Specified Name

Component

Zolpidem

Property

PrThr

Time

Pt

System

Saliva

Scale

Ord

Method

Screen

Additional Names

Short Name

Zolpidem Sal Ql Scn

Display Name

Zolpidem Screen Ql (Sal)

Consumer Name Alpha Get Info

Zolpidem, Saliva

Example Answer List: LL360-9

Basic Attributes

Class

DRUG/TOX

Type

Laboratory

First Released

Version 2.63

Last Updated

Version 2.73

Order vs. Observation

Both

Common Test Rank Get Info

5653

Member of these Groups Get Info

Language Variants Get Info

Related Names

• Addiction
• Adormix
• Ambien
• Ambien CR
• Damixan
• DRUG/TOXICOLOGY
• Drugs
• Drugs of abuse
• Edluar
• Hypnogen
• Illicit
• Ivedal
• Lioran
• Myslee
• Nasen
• Nytamel
• Oral fluid
• Ordinal
• Point in time
• PotentialForAbuse
• PR
• QL
• Qual
• Qualitative
• Random
• Sal
• Sanval
• Scn
• Scr
• Screen
• Scrn
• Somidem
• Stilnoct
• Stilnox
• Stilnox CR
• Sucedal
• Zoldem
• Zolpihexal
• Zolpimist

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