LOINC
Version 2.67

87820-7Zolpidem [Presence] in Saliva (oral fluid) by Screen methodActive

Part Descriptions

LP17255-8   Zolpidem
Zolpidem is a prescription medication used for the short-term treatment of insomnia, as well as some brain disorders. It is a short-acting nonbenzodiazepine hypnotic that potentiates gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, by binding to gamma-aminobutyric acid (GABAA) receptors at the same location as benzodiazepines. Trade names of zolpidem include Adormix, Ambien, Ambien CR, Edluar, Zolpimist, Damixan, Hypnogen, Ivedal, Lioran, Myslee, Nasen, Nytamel, Sanval, Somidem, Stilnoct, Stilnox, Stilnox CR, Sucedal, Zoldem, Zolnod and Zolpihexal.

Zolpidem has not adequately demonstrated effectiveness in maintaining sleep. Its hypnotic effects are similar to those of the benzodiazepine class of drugs, but it is molecularly distinct from the classical benzodiazepine molecule and is classified as an imidazopyridine. Flumazenil, a benzodiazepine receptor antagonist, which is used for benzodiazepine overdose, can also reverse zolpidem's sedative/hypnotic and memory impairing effects. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP7565-7   Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. [PMID: 17268583] Source: Regenstrief LOINC

LP262420-5   Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. [PMID: 17268583] Source: Regenstrief LOINC

Fully-Specified Name

Component
Zolpidem
Property
PrThr
Time
Pt
System
Saliva
Scale
Ord
Method
Screen

Additional Names

Short Name
Zolpidem Sal Ql Scn
Display Name
Zolpidem Screen Ql (Sal)

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.63
Last Updated
Version 2.63
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Groups

LG37621-6 Zolpidem|ANYProp|ANYTm|ANYSys|ANYMeth

Language Variants Get Info

zh-CNChinese (CHINA)
唑吡坦:存在情况或阈值:时间点:唾液:序数型:毒理学筛查试验
nl-NLDutch (NETHERLANDS)
zolpidem:aanwezigheid:moment:speeksel:ordinaal:screening
fr-BEFrench (BELGIUM)
Zolpidem:PrThr:Temps ponctuel:Salivaire:Ordinal:Dépistage
fr-CAFrench (CANADA)
Zolpidem:Présence-Seuil:Temps ponctuel:Salivaire:Ordinal:Dépistage
fr-FRFrench (FRANCE)
Zolpidem:Présence/Seuil:Ponctuel:Salive:Qualitatif:Dépistage
it-ITItalian (ITALY)
Zolpidem:PrThr:Pt:Saliva:Ord:Screening
ru-RURussian (RUSSIAN FEDERATION)
Золпидем:PrThr:ТчкВрм:Слюна:Пор:Скрининг
es-ESSpanish (SPAIN)
Zolpidem:PrThr:Punto temporal:Saliva:Ord:Cribado toxicológico
tr-TRTurkish (TURKEY)
Zolpidem:MevcEşik:Zmlı:Tükürük:Srl:Tarama

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=87820-7