87821-5
Zolpidem [Mass/volume] in Saliva (oral fluid) by Confirmatory method
Discouraged
Status Information
- Status
- DISCOURAGED
- Comment
- The Method values "Screen" and "Confirm" reflect a regulatory testing requirement rather than an actual laboratory method. This term has been discouraged in favor of terms specifying the true method (Immunoassay or Mass Spectrometry) or a methodless term where appropriate. Please select the replacement term that matches your actual testing method.
Part Descriptions
LP17255-8 Zolpidem
Zolpidem is a prescription medication used for the short-term treatment of insomnia, as well as some brain disorders. It is a short-acting nonbenzodiazepine hypnotic that potentiates gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, by binding to gamma-aminobutyric acid (GABAA) receptors at the same location as benzodiazepines. Trade names of zolpidem include Adormix, Ambien, Ambien CR, Edluar, Zolpimist, Damixan, Hypnogen, Ivedal, Lioran, Myslee, Nasen, Nytamel, Sanval, Somidem, Stilnoct, Stilnox, Stilnox CR, Sucedal, Zoldem, Zolnod and Zolpihexal.
Zolpidem has not adequately demonstrated effectiveness in maintaining sleep. Its hypnotic effects are similar to those of the benzodiazepine class of drugs, but it is molecularly distinct from the classical benzodiazepine molecule and is classified as an imidazopyridine. Flumazenil, a benzodiazepine receptor antagonist, which is used for benzodiazepine overdose, can also reverse zolpidem's sedative/hypnotic and memory impairing effects.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia,
Wikipedia
LP7565-7 Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583
Source: Regenstrief LOINC
LP262420-5 Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Zolpidem:
MCnc: Pt: Saliva: Qn: Confirm - Long Common Name
- Zolpidem [Mass/volume] in Saliva (oral fluid) by Confirmatory method
- Short Name
- Zolpidem Sal Cfm-mCnc
- Display Name
- Zolpidem Confirm (Sal) [Mass/Vol]
- Consumer Name Alpha Get Info
- Zolpidem, Saliva
Part Model Get Info
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.63
- Last Updated
- Version 2.83 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 8231
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG37621-6 | Zolpidem| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Zolpidem: |
| el-GR | Greek (Greece) | Ζολπιδέμη: Synonyms: DRUG/TOX MCnc Pt Qn Επιβεβαίωση Ζολπιδέμη Σίελος |
| es-ES | Spanish (Spain) | Zolpidem: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Zolpidem: |
| et-EE | Estonian (Estonia) | Tsolpideem: Synonyms: Juhuslik Kvantitatiivne Sülg |
| fr-CA | French (Canada) | Zolpidem: |
| fr-FR | French (France) | Zolpidem: |
| fr-BE | French (Belgium) | Zolpidem: |
| it-IT | Italian (Italy) | Zolpidem: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | zolpidem: |
| pl-PL | Polish (Poland) | Zolpidem: Synonyms: metoda potwierdzenia |
| ru-RU | Russian (Russian Federation) | Золпидем: Synonyms: Количественный Массовая концентрация Точка во времени; |
| tr-TR | Turkish (Turkey) | Zolpidem: Synonyms: Teyid |
| zh-CN | Chinese (China) | 唑吡坦: Synonyms: 佐尔吡啶; |
Example Units
| Unit | Source |
|---|---|
| ng/mL | Example UCUM Units |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://