87824-9

6-Beta naltrexol [Mass/volume] in Saliva (oral fluid) by Confirmatory method

Active

Part Descriptions

LP220262-2 6-Beta naltrexol
Naltrexol has two forms: 6-beta naltrexol and 6-alpha naltrexol. 6-Beta naltrexol (6β-Naltrexol) is the major urinary metabolite of Naltrexone in man and has a significant pharmacological activity and a longer elimination half-life than the parent drug. PMID: 9248940 Naltrexone is an opioid antagonist used primarily in the management of alcohol dependence and opioid dependence. Relative to naltrexone, 6β-naltrexol has about half the affinity for the μ-opioid receptor, but is present at approximately 10-30-fold higher concentrations at steady state due to extensive first-pass metabolism of the parent drug. Source: Regenstrief LOINC, 6β-Naltrexol

LP7565-7 Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583 Source: Regenstrief LOINC

LP262420-5 Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: 6-Beta naltrexol:MCnc:Pt:Saliva:Qn:Confirm
Long Common Name: 6-Beta naltrexol [Mass/volume] in Saliva (oral fluid) by Confirmatory method
Short Name: 6-Beta naltrexol Sal Cfm-mCnc
Display Name: 6-Beta naltrexol Confirm (Sal) [Mass/Vol]
Consumer Name Alpha Get Info: 6-Beta naltrexol, Saliva

Part Model Get Info

Component
6-Beta naltrexol
LP220262-2
- Analyte
  6-Beta naltrexol
  LP220262-2
  - Component Numerator
    6-Beta naltrexol
    LP220262-2
    - Component Numerator Core
      6-Beta naltrexol
      LP220262-2
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Saliva
LP7565-7
- System Core
  Saliva
  LP7565-7
- Super System
  NULL
Scale
Qn
LP7753-9
Method
Confirm
LP6197-0

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 2.63
Last Updated: Version 2.63 (ADD)
Order vs. Observation: Both

Member of these Groups Get Info

LOINC Group	Group Name
LG37740-4	6-Beta naltrexol\|ANYProp\|ANYTm\|ANYSys\|ANYMeth

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	6-beta-naltrexol:Hmotnostní koncentrace:Časový bod:Sliny:Kvantitativní:Konfirmace
el-GR	Greek (Greece)	6-β ναλτρεξόλη:MCnc:Pt:Σίελος:Qn:Επιβεβαίωση Synonyms: 6-β ναλτρεξόλη DRUG/TOX MCnc Pt Qn Επιβεβαίωση Ναλτρεξόλη Σίελος
es-ES	Spanish (Spain)	6-beta naltrexol:Concentración de masa:Punto temporal:Saliva:Qn:Confirmatorio Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	6-Beta naltrexol:Concentración de masa:Punto temporal:Saliva:Cuantitativo:Confirmar
fr-FR	French (France)	6-Bêta-naltréxol:Masse/Volume:Ponctuel:Salive:Numérique:Confirmation
it-IT	Italian (Italy)	6-beta naltrexolo:MCnc:Pt:Saliva:Qn:Conferma Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio)
nl-NL	Dutch (Netherlands)	6-bèta-naltrexol:massa/volume:moment:speeksel:kwantitatief:bevestiging
pl-PL	Polish (Poland)	6-Beta naltreksol:stężenie masowe:punkt w czasie:ślina:ilościowy:potwierdzenie Synonyms: metoda potwierdzenia
zh-CN	Chinese (China)	6-beta 纳曲醇:质量浓度:时间点:唾液:定量型:毒理学确认试验 Synonyms: 6-β纳曲醇;6-β-纳曲醇;6-β-naltrexol;盐酸纳曲酮主要活性代谢产物 B β 可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间毒品毒品类水平;浓度;质量浓度(单位体积) 津;津液;涎确认方法;确认法;确认试验药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类贝塔

Example Units

Unit	Source
ng/mL	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=87824-9

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.