88004-7

Trisomy 18 risk based on maternal age + Pregnancy associated plasma protein A + Choriogonadotropin + Nuchal translucency [Likelihood] in Fetus

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Part Description

LP263692-8 Trisomy 18 risk based on maternal age + Pregnancy associated plasma protein A + Choriogonadotropin + Nuchal translucency
The fetus's risk of having trisomy 18 can be estimated based on maternal age, fetal nuchal translucency (NT) thickness, and maternal serum or plasma levels for free beta-human chorionic gonadotropin (beta-hCG) and pregnancy-associated plasma protein-A (PAPP-A). PMID: 18726925 Reliable risk calculations for trisomy 18 and other trisomies (13, 21) in first-trimester screening depends on good estimates of the medians for fetal NT thickness, free beta-hCG, and PAPP-A from unaffected pregnancies. PMID: 21576269 Trisomy 18, also called Edwards syndrome, is caused by the presence of three copies of chromosome 18 in each cell rather than two. Edwards syndrome is associated with intrauterine growth retardation and fetal demise, and liveborn infants with Edwards syndrome typically have low birth weight, congenital heart disease, and characteristic physical features. Less than 10% of liveborn infants with Edwards syndrome live past their first year. The general population risk of Edwards syndrome is 1 out of 5,000 live births, and the risk for Edwards syndrome increases with increasing maternal age. [GMedlinePlus Condition: trisomy-18] Source: Regenstrief LOINC

Fully-Specified Name

Component: Trisomy 18 risk based on maternal age + Pregnancy associated plasma protein A + Choriogonadotropin + Nuchal translucency
Property: Likelihood
Time: Pt
System: ^Fetus
Scale: Qn
Method

Additional Names

Long Common Name: Trisomy 18 risk based on maternal age + Pregnancy associated plasma protein A + Choriogonadotropin + Nuchal translucency [Likelihood] in Fetus
Short Name: Ts 18 risk-age+PAPPA+HCG+NT Fetus
Display Name: Trisomy 18 risk based on maternal age + Pregnancy associated plasma protein A + Choriogonadotropin + Nuchal translucency Qn (fetus)
Consumer Name Alpha Get Info: Fetal Trisomy 18 Risk Based on Maternal Age + Pregnancy Associated Plasma Protein A + Choriogonadotropin + Nuchal Translucency

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.63
Last Updated: Version 2.63 (ADD)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Κίνδυνος τρισωμίας 18 με βάση την ηλικία της μητέρας + Πρωτεΐνη Α πλάσματος σχετιζόμενη με την εγκυμοσύνη + Χοριακή γοναδοτροπίνη + Αυχενική διαφάνεια:Πιθανότητα:Pt:^Έμβρυο:Qn: Synonyms: A Ηλικία Κίνδυνος τρισωμίας 18 Κίνδυνος τρισωμίας 18 με βάση την ηλικία της μητέρας + Πρωτεΐνη Α πλάσματος σχετιζόμενη με την εγκυμοσύνη + Χοριακή γοναδοτροπίνη + Αυχενική διαφάνεια Κύηση Πιθανότητα Πλάσμα Πρωτεΐνη Σχετιζόμενη με την Εγκυμοσύνη Πρωτεΐνη Πλάσματος-Α Χοριακή γοναδοτροπίνη
es-ES	Spanish (Spain)	Trisomía 18 del riesgo basada en la edad materna + Embarazo proteína plasmática A asociada al embarazo + Coriogonadotropina + translucencia nucal:Probabilidad:Punto temporal:^Feto:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Riesgo de trisomía 18 según la edad materna + Proteína plasmática A asociada al embarazo + Coriogonadotropina + Translucidez de la nuca:Probabilidad:Punto temporal:^ Feto:Cuantitativo:
fr-FR	French (France)	Risque Trisomie 18 basé sur l'âge maternel+pregnancy associated plasma protein A +Gonadotropine+clarté nucale:Probabilité:Ponctuel:Concerne le foetus:Numérique:
it-IT	Italian (Italy)	Trisomia 18, rischio basato sull'età materna + Proteina A plasmatica associata alla gravidanza + Coriogonadotropina + Translucenza nucale:Probabilità:Pt:^feto:Qn: Synonyms: Chimica Punto nel tempo (episodio) Rischio di trisomia 18 Rischio di trisomia 18 in base all''età materna
zh-CN	Chinese (China)	基于母亲年龄+妊娠相关血浆蛋白 A +绒毛膜促性腺激素+颈项透明层的三体型 18 风险:似然性:时间点:^胎儿:定量型: Synonyms: 18 三体型综合征风险（危险性、风险性、危险）;18 三体型风险;18 三体性综合征风险;18 三体性风险;18 三体综合征风险;18 号染色体三体型风险;18 号染色体三体性风险;T18 风险;Ts 18 风险;三体性 18 风险;染色体 18 三体型风险;染色体 18 三体性风险;爱德华兹综合征风险;Edwards 综合征风险;Edward 综合征风险 A 型 CG;HCG;人绒毛膜促性腺激素;人绒毛膜促性腺激素;Human chorionic gonadotropin;人绒膜促性腺激素;妊娠试验;妊娠试验;Pregnancy test;早早孕试验;总 CG;总 HCG;总绒毛膜促性腺激素;早早孕试验;绒毛膜促性腺激素;Chorionic gonadotropin;绒毛膜促性腺激素总量;绒膜促性腺激素 PAPP-A;妊娠相关性血浆蛋白 A;妊娠相关性血浆蛋白-A;妊娠相关血浆蛋白 A（Pregnancy Associated Plasma Protein A，PAPP-A）;妊娠相关血浆蛋白-A PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质 Ts 18 风险-年龄;基于产妇年龄的 18 三体综合征风险;基于产妇年龄的三体型 18 风险;基于产妇年龄的三体性 18 风险;基于妊娠妇女年龄的 18 三体综合征风险;基于妊娠妇女年龄的三体型 18 风险;基于妊娠妇女年龄的三体性 18 风险;基于孕妇年龄的三体型 18 风险;基于孕妇年龄的三体性 18 风险;基于母亲年龄的 18 三体综合征风险;基于母亲年龄的三体性 18 风险三体型三体细胞三染色体性三染色体细胞关联的化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺可能性;似然;可能基于母亲（孕妇、产妇、孕产妇）年龄+ 妊娠相关血浆蛋白 A（PAPPA）+绒毛膜促性腺激素（HCG、人绒毛膜促性腺激素）+颈项透明层（颈项透明带、颈项皮肤、颈项半透明物、颈部透明带、颈背透明层、颈部透明层、颈部透明性）的三体型 18 （18 三体型综合征、18 三体型、18 三体性综合征、18 三体性、18 三体综合征、18 号染色体三体型、18 号染色体三体性、T18 、Ts 18 、三体性 18 、染色体 18 三体型、染色体 18 三体性、爱德华兹综合征、Edwards 综合征、Edward 综合征怀孕;怀孕期;妊娠期时刻;随机;随意;瞬间有联系的相关的胎;超系统 - 胎儿血液制品 - 血浆

Example Units

Unit	Source
{risk}	Example UCUM Units

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