Version 2.80

Description

The fetus's risk of having trisomy 18 can be estimated based on maternal age, fetal nuchal translucency (NT) thickness, and maternal serum or plasma levels for free beta-human chorionic gonadotropin (beta-hCG) and pregnancy-associated plasma protein-A (PAPP-A). PMID: 18726925 Reliable risk calculations for trisomy 18 and other trisomies (13, 21) in first-trimester screening depends on good estimates of the medians for fetal NT thickness, free beta-hCG, and PAPP-A from unaffected pregnancies. PMID: 21576269 Trisomy 18, also called Edwards syndrome, is caused by the presence of three copies of chromosome 18 in each cell rather than two. Edwards syndrome is associated with intrauterine growth retardation and fetal demise, and liveborn infants with Edwards syndrome typically have low birth weight, congenital heart disease, and characteristic physical features. Less than 10% of liveborn infants with Edwards syndrome live past their first year. The general population risk of Edwards syndrome is 1 out of 5,000 live births, and the risk for Edwards syndrome increases with increasing maternal age. [GMedlinePlus Condition: trisomy-18] Source: Regenstrief LOINC

Basic Part Properties

Part Name
Trisomy 18 risk based on maternal age + Pregnancy associated plasma protein A + Choriogonadotropin + Nuchal translucency
Part Display Name
Trisomy 18 risk based on maternal age + Pregnancy associated plasma protein A + Choriogonadotropin + Nuchal translucency
Part Type
Component (Describes the core component or analyte measured)
Created On
2017-10-04
Construct for LOINC Short Name
Ts 18 risk-age+PAPPA+HCG+NT

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP263692-8

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 基于母亲年龄+妊娠相关血浆蛋白 A +绒毛膜促性腺激素+颈项透明层的三体型 18 风险
Synonyms: 基于母亲（孕妇、产妇、孕产妇）年龄+ 妊娠相关血浆蛋白 A（PAPPA）+绒毛膜促性腺激素（HCG、人绒毛膜促性腺激素）+颈项透明层（颈项透明带、颈项皮肤、颈项半透明物、颈部透明带、颈背透明层、颈部透明层、颈部透明性）的三体型 18 （18 三体型综合征、18 三体型、18 三体性综合征、18 三体性、18 三体综合征、18 号染色体三体型、18 号染色体三体性、T18 、Ts 18 、三体性 18 、染色体 18 三体型、染色体 18 三体性、爱德华兹综合征、Edwards 综合征、Edward 综合征
es-ES Spanish (Spain) Trisomía 18 del riesgo basada en la edad materna + Embarazo proteína plasmática A asociada al embarazo + Coriogonadotropina + translucencia nucal
it-IT Italian (Italy) Trisomia 18, rischio basato sull'età materna + Proteina A plasmatica associata alla gravidanza + Coriogonadotropina + Translucenza nucale
el-GR Greek (Greece) Κίνδυνος τρισωμίας 18 με βάση την ηλικία της μητέρας + Πρωτεΐνη Α πλάσματος σχετιζόμενη με την εγκυμοσύνη + Χοριακή γοναδοτροπίνη + Αυχενική διαφάνεια
Synonyms: Κίνδυνος τρισωμίας 18 με βάση την ηλικία της μητέρας + Πρωτεΐνη Α πλάσματος σχετιζόμενη με την εγκυμοσύνη + Χοριακή γοναδοτροπίνη + Αυχενική διαφάνεια