Version 2.80

Term Description

Elevated alanine levels is suggestive of a metabolic disorder. Since alanine levels can fluctuate depending on dietary intake, the alanine to lysine ratio is used to adjust for dietary variation. Normal alanine to lysine ratio is less than 3:1. An elevated alanine along with a elevated alaine:lysine ratio (>3) suggests true hyperalaninemia. PMID: 18243024

Part Descriptions

LP15331-9   Alanine
Alanine is a non-essential amino acid that exists as two distinct enantiomers: L-alanine and D-alanine. Alanine is one of the primary amino acids (secondary to leucine) used for protein construction. It is produced from pyruvate, exists in high levels in plasma, and is involved in the metabolism of sugar and organic acids.[PubChem: Alanine] Alanine acts as a substrate for alanine aminotransferase (ALT), an enzyme commonly measured to determine liver health. Increased alanine levels are seen in patients with lactic acidosis, carbamoyl phosphate synthetase deficiency, histidinemia, hyperprolinemia, and ornithine transcarbamylase deficiency. In patients with a mitochondrial disease, elevated alanine levels are primarily seen during times of physiologic stress or regression. PMID: 18243024 Source: Regenstrief LOINC

LP263693-6   Lysine
Lysine is an essential basic amino acid that plays a major role in calcium absorption and the production of hormones, enzymes, and antibodies. Lack of lysine can result in niacin deficiency and cause the pellagra. Other diseases associated with lysine include hyperlysinemia, lysine intolerance, carbamoyl phosphate synthetase deficiency, and saccharopinuria (saccharopine is an intermediate in the metabolism of lysine). Source: Regenstrief Institute

Fully-Specified Name

Component
Alanine/Lysine
Property
MRto
Time
Pt
System
Bld.dot
Scale
Qn
Method

Additional Names

Long Common Name
Alanine/Lysine [Mass Ratio] in DBS
Short Name
Alanine/Lysine DBS
Display Name
Alanine/Lysine (DBS) [Mass ratio]
Consumer Name Alpha Get Info
Alanine/Lysine, Dried blood spot

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.63
Last Updated
Version 2.63 (ADD)
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Αλανίνη/Λυσίνη:MRto:Pt:Bld.dot:Qn:
Synonyms: MRto Αλανίνη Λυσίνη
es-ES Spanish (Spain) Alanina/Lisina:Relacion de Masa:Punto temporal:gota de sangre (papel de filtro):Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Alanina / Lisina:Relación de masa:Punto temporal:DBS:Cuantitativo:
fr-FR French (France) Alanine/lysine:Masse ratio:Ponctuel:Sang buvard:Numérique:
it-IT Italian (Italy) Alanina/Lisina:MRto:Pt:Sangue.su carta da filtro:Qn:
Synonyms: Chimica Punto nel tempo (episodio) Rapporto di Massa Sangue Spot sangue secco
zh-CN Chinese (China) 丙氨酸/赖氨酸:质量比率:时间点:全血.斑点:定量型:
Synonyms: 2,6-二氨基已酸;Lys;氨基已氨酸;溶细胞素 Ala;Alpha 丙氨酸;Alpha-丙氨酸;L-Ala;L-丙氨酸;α丙氨酸;α-丙氨酸;丙胺酸 全血斑点(滤纸);滤纸;血液.斑点;血液斑点(滤纸) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 来自于同一体系的两种分析物的质量之比;质量比 血;血液

Example Units

Unit Source
{ratio} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=88018-7