88111-0

Gentamicin [Moles/volume] in Serum or Plasma --random post extended interval dosing

Active

Part Descriptions

LP15747-6 Gentamicin
Gentamicin is an aminoglycoside antibiotic, which has a bactericidal mode of action binding to the ribosome and various ribozymes to inhibit protein synthesis. Gentamicin is a hydrophilic molecule and is considered to have limited capacity to penetrate eukaryotic cells. Administered intravenously or intramuscularly, gentamicin is used to treat many bacterial infections, particularly gram-negative organisms such as meningitis, and infections of the blood, abdomen, lungs, skin, bones, joints and urinary tract, and is often used to treat severe cases of tularemia and the plague. The effect of gentamicin is mediated through the production of reactive oxygen species (ROS), which causes destablization of iron-sulfur (Fe-S) clusters and generates toxic, bactericidal compounds through the Fenton reaction. Gentamicin may cause kidney, nerve and severe hearing problems. More common side effects include nausea, headache, fever, rash and hoarseness. PMID: 26503658 [MedlinePlus Drug:a682275] Source: Regenstrief LOINC

LP29305-7 random post extended interval dosing
Extended interval (once daily) dosing of aminoglycosides may be less nephrotoxic than conventional dosing methods. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Gentamicin^random post extended interval dosing:SCnc:Pt:Ser/Plas:Qn:
Long Common Name: Gentamicin [Moles/volume] in Serum or Plasma --random post extended interval dosing
Short Name: Gentamicin Rand EID SerPl-sCnc
Display Name: Gentamicin rando Min post extended interval dosing [Moles/Vol]
Consumer Name Alpha Get Info: Gentamicin rando min after Extended Interval Dosing, Blood

Part Model Get Info

Component
Gentamicin^random post extended interval dosing
LP307920-1
- Analyte
  Gentamicin
  LP15747-6
  - Component Numerator
    Gentamicin
    LP15747-6
    - Component Numerator Core
      Gentamicin
      LP15747-6
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  random post extended interval dosing
  LP29305-7
- Adjustment
  NULL
- Count
  NULL
Property
SCnc
LP6860-3
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 2.63
Last Updated: Version 2.63 (MIN)
Order vs. Observation: Both

Member of these Groups Get Info

LOINC Group	Group Name
LG50412-2	Gentamicin^random post extended interval dosing\|Pt\|Ser/Plas

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Gentamicin^Náhodný po prodlouženém intervalu dávkování:Látková koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
el-GR	Greek (Greece)	Γενταμυκίνη^τυχαία κατόπιν δόσης παρατεταμένου διαστήματος:SCnc:Pt:Ορός/Πλάσμα:Qn: Synonyms: DRUG/TOX Pt Qn SCnc Γενταμυκίνη Ορός Ορός/Πλάσμα Πλάσμα τυχαία κατόπιν δόσης παρατεταμένου διαστήματος τυχαίο
es-ES	Spanish (Spain)	Gentamicina^aleatoria tras prolongación del intervalo posológico:Concentración de sustancia:Punto temporal:Suero o Plasma:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Gentamicina ^ dosis aleatoria posterior a intervalos prolongados:Concentración de sustancias:Punto temporal:Suero o Plasma:Cuantitativo:
fr-CA	French (Canada)	Gentamicine^Au hasard post dose intervalle prolongé:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR	French (France)	Gentamicine^aléatoire après un intervalle posologique allongé:Moles/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE	French (Belgium)	Gentamicine^Au hasard post dose intervalle prolongé:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT	Italian (Italy)	Gentamicina^random post lungo intervallo dosaggio:SCnc:Pt:Siero/Plasma:Qn: Synonyms: Concentrazione di Sostanza Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) random dopo lungo intervallo di dosaggio Siero Siero o Plasma TDM Random
nl-NL	Dutch (Netherlands)	gentamicine^willekeurig na langdurige intervaldosering:mol/volume:moment:serum of plasma:kwantitatief:
ru-RU	Russian (Russian Federation)	Гентамицин^произвольный после расширения интервала дозирования:МолКонц:ТчкВрм:Сыв/Плаз:Колич: Synonyms: Количественный Молярность;Молярная объёмная концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	Gentamisin^rastgele genişleltilmiş aralıklı dozlama:SubKons:Zmlı:Ser/Plaz:Kant:
zh-CN	Chinese (China)	庆大霉素^在延长时间间隔剂量给药之后随机时间:物质的量浓度:时间点:血清/血浆:定量型: Synonyms: EID XXX刺激 - 在...之后之后于... 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 可用数量表示的;定量性;数值型;数量型;连续数值型标尺在...以后在后在延长时间间隔剂量给予氨基糖苷类药物之后随机时间;在延长时间间隔定量给予氨基糖苷类药物之后随机时间;在延长时间间隔定量给药之后随机时间延长时间间隔给药（Extended interval dosing，EID）延长时间间隔给药剂量给药延长间隔给药延长间隔给药剂量给药时刻;随机;随意;瞬间正泰霉素;艮他霉素毒品毒品类治疗药物监测 - 随机;随机药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类血清或血浆

Example Units

Unit	Source
umol/L	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=88111-0

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.