88304-1

Kappa light chains [Presence] in 24 hour Urine by Immunofixation

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Part Descriptions

LP15030-7 Immunoglobulin light chains.kappa
All immunoglobulins contain two polypeptide chains: a long (heavy) and a short (light) chain. The two chains interact via disulfide bonds. There are two types of light chains, named kappa and lambda. Serum free light chain (SFLC) testing, a kappa/lambda ratio and a protein electrophoresis test are done to help detect, diagnose and monitor plasma cell disorders (dyscrasias) including multiple myeloma and primary amyloidosis. Normal readings are seen when there is a kappa/lambda ratio of approximately 0.26 to 1.65 and free light chains are present in the blood at low levels. Increased kappa free light chains and an increased kappa/lambda ratio are present with plasma cell disorders that produce excess monoclonal kappa light chains. The tests can also be used to monitor response to treatment. An increase in serum free light chains along with an abnormal kappa/lambda ratio may indicate primary amyloidosis; biopsy of affected tissue is typically used for confirmation of diagnosis. PMID: 6802926 ] [Lab Tests Online:free-light/tab/test] Source: Regenstrief LOINC

LP6336-4 Immunofixation
Plasma or concentrated urine is deposited on a gel. With an electrical current the proteins are sorted in function of their size, after which antigens for each targeted type of immunoglobulin are deposited on the gel. Thus more or less narrow bands appear on the gel, marking the location of the various immunoglobulines.
Immunofixation tends to replace protein electrophoresis because:

• it is faster (results within three hours);
• it is somewhat more sensitive. Immunofixation may reveal an immunoglobulin missed out by protein electrophoresis, especially at low concentrations (less than 1 gram/litre);
• it can be partially automated and can be used in more laboratories;
• it is more easily read and interpreted.

Immunofixation is however only sensitive to immunoglobulins and is more expensive than protein electrophoresis. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Immunofixation

Fully-Specified Name

Component: Immunoglobulin light chains.kappa
Property: PrThr
Time: 24H
System: Urine
Scale: Ord
Method: Immunofixation

Additional Names

Short Name: Kappa LC 24h Ur Ql IFE
Display Name: Immunoglobulin light chains.kappa Immunofixation Ql (24H U)
Consumer Name Alpha Get Info: Immunoglobulin light chains.kappa, Urine

Example Answer List: LL744-4

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.64
Last Updated: Version 2.64
Order vs. Observation: Both

Member of these Groups Get Info

LOINC Group	Group Name
LG17765-5	Immunoglobulin light chains.kappa\|PrThr\|24H\|ANYUrine
LG36220-8	Immunoglobulin light chains.kappa\|PrThr\|Urine

Language Variants Get Info

Tag	Language	Translation
es-ES	Spanish (Spain)	Cadenas ligeras de las inmunoglobulinas.kappa:PrThr:24 horas:Orina:Ord:Inmunofijación
es-MX	Spanish (Mexico)	Cadenas ligeras de inmunoglobulina kappa:Presencia o umbral:24H:Orina:Ordinal:Inmunofijación
et-EE	Estonian (Estonia)	Immuunoglobuliini kerged ahelad.kapa:PrThr:24 tunni:U:Ord:Immuunfiksatsioon Synonyms: Immuunglobuliinide kerged kapaahelad Järgarvuline Uriin
fr-CA	French (Canada)	Chaînes légères d'immunoglobulines.kappa:Présence-Seuil:24 h:Urine:Ordinal:Immunofixation
fr-FR	French (France)	Immunoglobuline chaines légères kappa:Présence/Seuil:24H:Urine:Qualitatif:Immunofixation
fr-BE	French (Belgium)	Chaînes légères immunoglobulines.kappa:PrThr:24 h:Urine:Ordinal:Immunofixation Synonyms: LC LC. Kappa
it-IT	Italian (Italy)	Immunoglobuline, catene leggere.kappa:PrThr:24h:Urine:Ord:Immunofissazione Synonyms: 24 Ore Catene leggere delle immunoglobuline Catene leggere kappa delle immunoglobuline Chimica Presenza o Soglia
nl-NL	Dutch (Netherlands)	immunoglobuline lichte ketens.kappa:aanwezigheid:24 uur:urine:ordinaal:immunofixatie Synonyms: 24U
pl-PL	Polish (Poland)	Łańcuchy lekkie immunoglobuliny.kappa:granica wykrywalności:24 godziny:mocz:półilościowy:immunofiksacja Synonyms: Łańcuchy lekkie immunoglobulin Łańcuchy lekkie kappa immunoglobuliny
ru-RU	Russian (Russian Federation)	Иммуноглобулин легкие цепи.каппа:PrThr:24 часа:Моча:Пор:Иммунофиксация Synonyms: Порядковый
tr-TR	Turkish (Turkey)	İmmünglobulin hafif zincirler.kappa:MevcEşik:24Sa:İdrar:Srl:İmmünfiksasyon Synonyms: Mevcut
zh-CN	Chinese (China)	免疫球蛋白轻链.Kappa 型:存在情况或阈值:24小时:尿液:序数型:免疫固定电泳分析法 Synonyms: 1天;1日;24.0小时;一天;一日;二十四个小时;二十四小时 Bence Jones 氏蛋白;Bence Jones 蛋白;BJ 蛋白;B-J 蛋白;BJP;本周氏蛋白;本-周氏蛋白;本周氏蛋白（Bence Jones protein，BJ Protein，BJP）;本周蛋白;本-周蛋白 IFE;Ifix;免疫固定法;免疫固定电泳（Immunofixation electrophoresis，IFE）;免疫固定电泳法 Ig Kappa LC;Kappa 型免疫球蛋白轻链;Kappa 型轻链;Kappa 轻链;κ型免疫球蛋白轻链;κ型轻链;κ轻链;免疫球蛋白轻链.Kappa;免疫球蛋白轻链.κ型;轻链.Kappa;轻链.Kappa 型;轻链.κ;轻链.κ型丙种球蛋白依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫球蛋白（Immunoglobulin，Ig）免疫球蛋白类化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）尿;小便;下泉链

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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.